SCS Designs 6, 7, and 8. by Matthew R. Lakin (649454)

“…We tested various lengths for the substrate binding arms of the upstream DNAzyme (denoted as 5′/3′ in the Figure). These results showed that longer substrate binding arms decrease the effect on activation rate by reducing the rate of product dissociation. …”

Data_Sheet_1_SUMOylation of Alpha-Synuclein Influences on Alpha-Synuclein Aggregation Induced by Methamphetamine.doc by Lin-nan Zhu (5681939)

“…Levels of the ubiquitin-proteasome system (UPS)-related makers ubiquitin (Ub) and UbE1, as well as the autophagy-lysosome pathway (ALP)-related markers LC3, P62 and lysosomal associated membrane protein 2A (LAMP2A), were also measured in SH-SY5Y cells transfected with lentivirus and mice injected with adenovirus. …”

Image_2_P300/CBP Associated Factor (PCAF) Deficiency Enhances Diet-Induced Atherosclerosis in ApoE3*Leiden Mice via Systemic Inhibition of Regulatory T Cells.JPEG by Alwin de Jong (4012250)

“…Expression of FoxP3 by systemic CD4⁺ T cells decreased 1.8 fold in ApoE3^*LeidenxPCAF^−/− after 5 months HFD and remained significantly reduced after 5 months of HFD. …”

Molecular Characterization of Acquired Tolerance of Tumor Cells to Picropodophyllin (PPP) by Jamileh Hashemi (131207)

“…Using Nexus software analysis we combined the array-CGH data with data from gene expression profilings and identified genes that were altered in both inputs. A subset of genes identified as downregulated (<em>ALDH1A3</em>, <em>ANXA1</em>, <em>TLR4</em> and <em>RAB5A</em>) or upregulated (<em>COX6A1</em>, <em>NFIX</em>, <em>ME1</em>, <em>MAPK</em> and <em>TAP2</em>) were validated by siRNA in the tolerant or parental cells to alter sensitivity to PPP and confirmed to alter sensitivity to PPP in further cell lines.…”

Metabolomics raw data and table of extracted peak areas for BT478, BT530 and NHA cells cultured in the presence of MPA, Compound 3 (IC80) or vehicle control, for 6 hours. by Agata Monika Kieliszek (14650298)

“…The linear gradient employed was as follows: 0–2.5 min 99% A, 2.5–7.5 min decrease to 80% A, 7.5–13 min to 55% B 652 and finally 13–15 min to 99% B and held for 1 min. …”

Table_1_Regulation of miRNA expression in the prefrontal cortex by fecal microbiota transplantation in anxiety-like mice.docx by Simin Chen (9549665)

“…MiRNA analysis identified five key miRNAs affecting GAD pathogenesis, including mmu-miR-10a-5p, mmu-miR-1224-5p, mmu-miR-218-5p, mmu-miR-10b-5p, and mmu-miR-488-3p. …”

Image_1_P300/CBP Associated Factor (PCAF) Deficiency Enhances Diet-Induced Atherosclerosis in ApoE3*Leiden Mice via Systemic Inhibition of Regulatory T Cells.JPEG by Alwin de Jong (4012250)

“…Expression of FoxP3 by systemic CD4⁺ T cells decreased 1.8 fold in ApoE3^*LeidenxPCAF^−/− after 5 months HFD and remained significantly reduced after 5 months of HFD. …”

Demography of normoxic and hypoxic flies by Paul Vigne (373124)

“…</p> <p>(A) Survivorship analysis.</p> <p>Hypoxia decreased the mean life span from 33.6±0.8 days (n = 79) to 6.3±0.1 days (n = 282).…”

The STIM2-TM domain activates the cytosolic region of STIMs less efficiently than that of STIM1. by Sisi Zheng (1574473)

“…Left: average time course of whole-cell I_CRAC currents measured at –100 mV. Currents mediated by STIM1121-ΔK developed significantly more slowly than control (time to peak, 72 ± 7 s versus 147 ± 9 s, <i>n</i> = 7, ****<i>P</i> < 0.0001, <i>t</i> test), with the maximal current density also reduced (–5.5 ± 0.8 pA/pF versus –1.5 ± 0.1 pA/pF, <i>n</i> = 7, *****<i>P</i> < 0.0004, <i>t</i> test). …”

Sequential responses of channel 10 in the frontal area to constant or increasing pain intensities. by Chih-Hung Lee (188177)

“…The traces are from channel 10 in the frontal area of subject M-1. (D) Mean (n = 4 subjects) peak responses in [HbO2] in channel10 in the frontal area when pain stimulation intensity was gradually increased (**<i>p</i><0.05, vs the response in the first stimulation (0.5 N)). …”

Building Strain with Large Macrocycles and Using It To Tune the Thermal Half-Lives of Hydrazone Photochromes by Quan Li (157017)

“…Strain has been used as a tool to modulate the reactivity (e.g., mechanochemistry) and thermal isomerization kinetics of photochromic compounds. …”

Building Strain with Large Macrocycles and Using It To Tune the Thermal Half-Lives of Hydrazone Photochromes by Quan Li (157017)

“…Strain has been used as a tool to modulate the reactivity (e.g., mechanochemistry) and thermal isomerization kinetics of photochromic compounds. …”

Probing Interaction between ssDNA and Carbon Nanotubes by Raman Scattering and Electron Microscopy by Masayuki Shoda (2380057)

“…We report experimental results of Raman scattering showing that single-stranded DNA (ssDNA) effectively modifies the electronic structure of metallic carbon nanotubes with the diameter of 1.5−1.6 nm but not for the same diameter class of semiconducting tubes. …”

Rad51 stimulates expression of integrated copies of HIV-1. by Rafal Kaminski (179554)

“…<p><b>(A)</b> TZM-bl cells multiple endogenous integrated copies of LTR-luciferase were transfected with 0, 3, 10 and 30 ng of pCMV (lanes 1–4 or 5–8, respectively). …”

Reduced but functional CD8+ T-cell compartment after fully-mismatched HLA class I thymus transplantation. by Adriana S. Albuquerque (323475)

“…<p>(A) Circulating CD8+ αβ T-cells analysed 58 months post-transplantation (5% of total lymphocytes; 83cells/µl) by flow cytometry in terms of: naïve/memory/effector phenotype assessed by CD45RA and CD27 expression; levels of activation markers (CD38 and HLA-DR); IFN-γ and IL-2 production upon PMA+ionomycin stimulation; <i>ex vivo</i> frequency of cycling cells (Ki-67+); and <i>ex vivo</i> frequency of apoptotic cells assessed by annexin V staining. …”

Building Strain with Large Macrocycles and Using It To Tune the Thermal Half-Lives of Hydrazone Photochromes by Quan Li (157017)

“…Strain has been used as a tool to modulate the reactivity (e.g., mechanochemistry) and thermal isomerization kinetics of photochromic compounds. …”

Oligomerization of hIKK2 dimers. by Smarajit Polley (420092)

“…(E) In vitro kinase assay reveals that catalytic activity of hIKK2 with mutations that disrupt the V-shaped interface (lanes 3–5) is drastically reduced compared to wild-type protein (WT-lane 2). …”

Building Strain with Large Macrocycles and Using It To Tune the Thermal Half-Lives of Hydrazone Photochromes by Quan Li (157017)

“…Strain has been used as a tool to modulate the reactivity (e.g., mechanochemistry) and thermal isomerization kinetics of photochromic compounds. …”

Supplementary Material for: Sensitivity of Blood Volume Monitoring for Fluid Status Assessment in Hemodialysis Patients by Maduell F. (4137250)

Specificity and sensitivity of C4BP and FH binding by <i>P. intermedia</i> ATCC 25611. by Sven Malm (326396)

“…<p>A) Binding of 250 kcpm ¹²⁵I-C4BP was competed by using 30 µg (final concentration 1.32 µM) unlabeled C4BP, C) ¹²⁵I-FH binding by <i>P. intermedia</i> ATCC 25611 was competed by 7.5 µg (final concentration 1.25 µM) unlabeled FH. …”