Hematoxylin–eosin and TUNEL staining of SD rat retinas showed progressive changes in the ONL thickness and photoreceptor apoptosis in the in vivo light-induced photoreceptor degene... by Meng Zhang (154027)

“…<p>(A–E) Compared with the normal group, the photoreceptor number and ONL thickness decreased markedly at different time points after exposure to light (black arrow). …”

Differential genome-wide distribution of epigenetic markers between HCV infected vs. non-infected cells and its integration with gene expression. by Shira Perez (6857819)

“…<p>(A) Change in genome-wide distribution of epigenetic marks following HCV infection (100% HCV infected Huh7.5 cells, generated as described in the <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008181#sec010" target="_blank">Methods</a>) determined by ChIP-seq experiments, as well as change in gene expression determined by RNA-seq experiment. …”

Case fatality of acute coronary events is improving even among elderly patients; the FINAMI study 1995–2012 by Heli Koukkunen (4486945)

“…The incidence of MI decreased by −3.3%/year (95% CI −4.2; −2.4) in women aged 75–84 years, and by −1.2%/year (−1.9; −0.5) in women aged 85-99 years, but among men in these age-groups, only a non-significant reduction occurred. …”

Genus and phylum composition of the feline faecal microbiome. by Oliver Deusch (497048)

“…The central circular plot illustrates the community structure at the phylum level (five most abundant phyla shown) allowing for quick inference of phylum level composition at a given age as well as temporal distribution of a phylum. …”

Influence of the Anion of the Salt Used on the Coordination Mode of an N-Heterocyclic Carbene Ligand to Osmium by Miguel Baya (1709560)

“…In the three cases, mixtures of the abnormal [OsH(η²-H₂){κ<i>C</i>⁵,<i>N</i>-[1-(2-pyridylmethyl)-3-methylimidazol-5-ylidene]}(PⁱPr₃)₂]A (A = BPh₄ (<b>2a</b>), BF₄ (<b>2b</b>), Br (<b>2c</b>)) and normal [OsH(η²-H₂){κ<i>C</i>²,<i>N</i>-[1-(2-pyridylmethyl)-3-methylimidazol-2-ylidene]}(PⁱPr₃)₂]A (A = BPh₄ (<b>3a</b>), BF₄ (<b>3b</b>), Br (<b>3c</b>)) isomers are obtained. …”

Analysis of vesicle recruitment to the RRP for models covered by Eq 1. by Kashif Mahfooz (2586439)

“…The exponential constant for acceleration (<i>τ</i> ⋅ <i>ν</i> in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1004855#pcbi.1004855.e026" target="_blank">Eq 2</a>) was 10 action potentials for 100<i>Hz</i> and 300<i>Hz</i> stimulation alike, and fatigue was modeled as a 10%/<i>s</i> linear decrease. …”

Influence of Fra on the heme maturation pathway. by Andreas Mielcarek (715578)

“…Data were fitted according to the Michaelis-Menten model, which resulted in a <i>K</i>_m(obs) of about 2.8 ± 0.5 μM and a <i>k</i>_cat(obs) of 0.925 ± 0.059 s^-1 (error bars represent SEM of three independent experiments). …”

Additional file 1 of Deficiency in nucleoside diphosphate kinase B leads to endothelial activation of the hexosamine biosynthesis pathway and cardiac dysfunction by Feng Shao (112229)

“…Sirius-red staining of whole heart (A) and statistical analysis in NDPKB-/- and WT LVs (B). n=5. …”

Arkadia Ubiquitinates P-Smad2 and Mediates Its Degradation via the Proteasome by Konstantinos J Mavrakis (25033)

“…Note the presence of high molecular weight species only in the reactions containing in vitro transcribed/translated full-length (Akd) or the C-Akd (aa 510–989) Arkadia proteins (see WB with anti-ubiquitin in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0050067#pbio-0050067-sg005" target="_blank">Figure S5</a>A). …”

Accuracy of consumer-level and research-grade activity trackers in ambulatory settings in older adults by Salvatore Tedesco (6029417)

“…Gold-standards included treadmill, ECG-based chest strap, direct observation or video recording according to the activity and parameter. Every tracker showed a decreasing accuracy with slower walking speed, which resulted in a significant step under-counting. …”

Synthesis, Structure, and Magnetic Properties of Dy₂Co₂<i>L</i>₁₀(bipy)₂ and <i>Ln</i>₂Ni₂<i>L</i>₁₀(bi... by Fang-Hua Zhao (2038318)

“…The 3,5-dichlorobenzoate anion, <i>L</i>^–, serves as a bridging ligand and 2,2′-bipyridine, bipy, as a terminal bidentate ligand to yield, through hydrothermal syntheses, the tetranuclear clusters Dy₂Co₂<i>L</i>₁₀(bipy)₂, <b>1</b>, and <i>Ln</i>₂Ni₂<i>L</i>₁₀(bipy)₂, where <i>Ln</i> is the trivalent La, <b>2</b>, Gd, <b>3</b>, Tb, <b>4</b>, Dy, <b>5</b>, or Ho, <b>6</b>, ion. …”

Spectroscopic and Theoretical Study of Cu^I Binding to His111 in the Human Prion Protein Fragment 106–115 by Trinidad Arcos-López (2542546)

“…The ability of the cellular prion protein (PrP^C) to bind copper in vivo points to a physiological role for PrP^C in copper transport. …”

Subgroup analysis. by Bruno Martins Tomazini (6509528)

“…<div><p>Background</p><p>Halofuginone (PJS-539) is an oral prolyl-tRNA synthetase inhibitor that has a potent <i>in vitro</i> activity against SARS-CoV-2 virus. …”

Study outcomes. by Bruno Martins Tomazini (6509528)

“…<div><p>Background</p><p>Halofuginone (PJS-539) is an oral prolyl-tRNA synthetase inhibitor that has a potent <i>in vitro</i> activity against SARS-CoV-2 virus. …”

Image 6_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.tif by Lan Wang (85307)

“…</p>Results<p>In this study, RNA sequencing (RNA-seq) was utilized to demonstrate that the upregulation of hnRNP-F in HK-2 cells cultured under high-glucose conditions resulted in a substantial decrease in the expression of genes associated with the inflammatory response and suppression of the TNFα-NFκB signaling pathway. …”

Table 3_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.xlsx by Lan Wang (85307)

“…</p>Results<p>In this study, RNA sequencing (RNA-seq) was utilized to demonstrate that the upregulation of hnRNP-F in HK-2 cells cultured under high-glucose conditions resulted in a substantial decrease in the expression of genes associated with the inflammatory response and suppression of the TNFα-NFκB signaling pathway. …”

Image 3_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.tif by Lan Wang (85307)

“…</p>Results<p>In this study, RNA sequencing (RNA-seq) was utilized to demonstrate that the upregulation of hnRNP-F in HK-2 cells cultured under high-glucose conditions resulted in a substantial decrease in the expression of genes associated with the inflammatory response and suppression of the TNFα-NFκB signaling pathway. …”

Table 7_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.xls by Lan Wang (85307)

“…</p>Results<p>In this study, RNA sequencing (RNA-seq) was utilized to demonstrate that the upregulation of hnRNP-F in HK-2 cells cultured under high-glucose conditions resulted in a substantial decrease in the expression of genes associated with the inflammatory response and suppression of the TNFα-NFκB signaling pathway. …”

Image 2_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.tif by Lan Wang (85307)

“…</p>Results<p>In this study, RNA sequencing (RNA-seq) was utilized to demonstrate that the upregulation of hnRNP-F in HK-2 cells cultured under high-glucose conditions resulted in a substantial decrease in the expression of genes associated with the inflammatory response and suppression of the TNFα-NFκB signaling pathway. …”

Image 1_Integrative RNA-seq and CLIP-seq analysis reveals hnRNP-F regulation of TNFα/NFκB signaling in high-glucose conditions.tif by Lan Wang (85307)

“…</p>Results<p>In this study, RNA sequencing (RNA-seq) was utilized to demonstrate that the upregulation of hnRNP-F in HK-2 cells cultured under high-glucose conditions resulted in a substantial decrease in the expression of genes associated with the inflammatory response and suppression of the TNFα-NFκB signaling pathway. …”