Effect of arterial pressure reduction and dextran infusion on functional vascular density (FVD). by Bumseok Namgung (813359)

“…Scale bar = 500 μm. (* <i>P</i> < 0.5, ** <i>P</i> < 0.005; significant decrease due to the dextran infusion.)…”

Hypotension-induced changes in pial arteriolar diameters. by Sébastien Foulquier (138858)

“…<p>Internal diameters of pial arterioles (ID, µm) during decrease in systemic mean arterial blood pressure (mmHg), <b>A</b>: in 4–5 month-old normotensive rats (WKY, empty circles) and hypertensive vehicle-treated rats (SHR, full triangles); and <b>B</b>: in hypertensive rats treated for 10 days with telmisartan (TELMI, 2 mg/kg per day, empty squares) or candesartan cilexetil (CANDE, 10 mg/kg per day, full squares). n = 4–8 per group, m±sem.…”

Effects of pH on functional activity of influenza vaccine. by Hyo-Jick Choi (420200)

“…<p>Hemagglutinating activity of vaccine in osmolyte solution (Δ = −150, 0, 150, 300, and 500 mosM) was measured after 1, 5, 15, 30, 60, 90, and 120 min of incubation at pH 2.0 and 37°C, and the remaining activity relative to control (pH 7.0 and 4°C) is plotted as a function of time. …”

Setup and experiments for sensor characterization. by Vlad Oncescu (526674)

“…<p>A) Schematic of the nanowire biosensor and picture of the flow through system B) demonstration of sensor reversibility C) resistance, and associated current, change due to continuous decrease in vasopressin concentration in sheep serum. …”

Identification of Aging-related metabolite biomarker. by Xi Chen (35903)

“…<p>(A) Two-way ANOVA test (q value <0.05) and RF analysis (Mean decrease accuracy >5) identify eight metabolites significantly affected by aging. …”

DataSheet_1_Multimodal analysis of granulocytes, monocytes, and platelets in patients with cystic fibrosis before and after Elexacaftor–Tezacaftor–Ivacaftor treatment.pdf by Hanna Schmidt (16465227)

“…T2: 3.0 ng/ml (2.2|3.7), p < 0.01) and a small but significant decrease in matrix metallopeptidase 9 (T1: 45.5 ng/ml (32.5|140.1) vs. …”

Overexpression or pharmacological activation of pgk1 rescues motor neuron phenotypes in smn morphant zebrafish. by Penelope J. Boyd (3936893)

“…(D) Bar chart (mean & s.e.m) showing activation of Pgk1 by treatment with 2.5 μM terazosin in <i>smn</i> morphant zebrafish at 30 hpf led to a significant increase in normal motor axons and significant decrease in severe axonal outgrowth phenotypes compared to untreated <i>smn</i> MO injected embryos. …”

Effect of variation in parameter used on method performance. by Stefano M. Marino (264307)

“…The graph should be read as follows: each parameter is represented by a curve, and each point represents the TPR-FPR value (the higher the better) for a specific weight. …”

Retrotransposon expression in <i>Pld6</i> KO and <i>Dnmt3l</i> KO spermatocytes. by Kota Inoue (4282273)

“…<p>(A) Expression of individual retrotransposons in <i>Pld6</i> KO and WT spermatocytes. …”

DNA2 has distinct effects on Alt-EJ and end resection, compared to FANCA and PARP. by Sean M. Howard (687174)

“…(<b>B)</b> PARPi treatment and DNA2 depletion cause an approximately additive decrease in Alt-EJ. U2OS EJ2-GFP cells were treated with siCTRL or siDNA2–4 prior to expression of I-SceI and treatment with 5 μM Olaparib (Olap) or vehicle (DMSO). …”

¹⁸F-FET MicroPET and MicroMRI for Anti-VEGF and Anti-PlGF Response Assessment in an Orthotopic Murine Model of Human Glioblastoma by Mette Kjoelhede Nedergaard (697584)

“…</p><p>Results</p><p>Anti-VEGF monotherapy increased survival and decreased ¹⁸F-FET uptake, BLI and MVD, while no additive effect of anti-PlGF was observed. …”

Reduced Aqueous Retinol Binding Protein 3 Concentration is Associated with Diabetic Macular Edema and Progression of Diabetic Retinopathy by Tanvi Chokshi (12970453)

“…</p><p dir="ltr">Results: In 153 eyes (31 with type 1 and 122 with type 2 diabetes; N=149 patients), 37% had no signs of DR, 40% had mild non-proliferative diabetic retinopathy (NPDR), and 23% moderate NPDR. Aqueous RBP3 decreased from a median of 2.1nM [IQR 0.8-3.4nM] in eyes with no DR to 1.5nM [0.8-3.8nM] in eyes with mild-moderate NPDR (P=0.047). …”

Hydrophobicity-related areas; and negatively charged-related areas modulated by the probe radius. by Dan V. Nicolau (390041)

“…<p>Left: hydrophobic area (a1, top); ratio of hydrophobic per total area (a2, middle); and relative decrease of the hydrophobic area, reported to its maximum extent at minimum probe radius, (a3, bottom) for five model proteins: 1LZY  =  lysozyme; 1AFU  =  ribonuclease-A; 1Y4F  =  human hemoglobin; 1AO6  =  human serum albumin; and 1HZH  =  intact human IgG. …”

Tumor inhibition in mouse model, and effects on EGFR expression and Akt phosphorylation. by Satoshi Inoue (221875)

“…<p>(5a) Tumor growth inhibition in mice. MDA-MB-468 subcutaneous breast tumors treated systemically with P/AON/2C5, or P/AON/2C5/TfR were significantly inhibited compared with PBS (control), P(polymer only), or P/2C5 (without anti-tumor component) (P<0.03). …”

IGF-1-induced enhancement of <i>PRNP</i> expression depends on the activation of PI3K-Akt signaling pathway. by Ting Liu (45625)

“…The LY294002-treated cells (lanes 2 and 6) showed a remarkable decrease in the PrP^C protein level compared with the DMSO-treated group (lanes 1 and 5). …”

Loss of <i>Hes1</i> impairs neural crest development. by Francesca Rochais (371680)

“…<p>(A) In situ hybridization at E9.5 showing decreased <i>Crabp1</i> transcript accumulation in the caudal pharyngeal region of <i>Hes1</i>^−/− compared to <i>Hes1</i>^+/+ embryos (arrowheads). …”

Application of bar-code to cell counting studies. by Irina Krylova (585893)

“…<b>D,</b> LNCaP-C4-2 cells mixed, co-plated, treated exactly as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0063286#pone-0063286-g005" target="_blank">figure 5B</a> then separated according to the bar-code showed similar treatment responses to the individually plated cells. …”

Reelin is secreted by GABAergic neurons. by Cecilia Gonzalez Campo (264260)

“…Treatment with BFA did not change the proportion of intense reelin IR neurons: 21.1±1.2% before treatment (n = 8) and 21.0±1.9% after 16 hours (n = 6), whereas it caused a significant decrease in the fraction of punctate reelin IR neurons. …”

Immunofluorescence localization of pectin epitopes in non-embryogenic cells (NECs) of banana (<i>Musa</i> spp. AAA, cultivar ‘Baxijiao’) and the effect of NaOH de-esterification on... by Chunxiang Xu (346832)

“…The LM5 epitope showing immunolocalization in NECs (H) and slight decrease of immunolabeling after base treatment (P). …”

Reduced Susceptibility of DNA Methyltransferase 1 Hypomorphic (Dnmt1^N/+) Mice to Hepatic Steatosis upon Feeding Liquid Alcohol Diet by Huban Kutay (144581)

“…<div><h3>Background</h3><p>Methylation at C-5 (5-mdC) of CpG base pairs, the most abundant epigenetic modification of DNA, is catalyzed by 3 essential DNA methyltransferases (Dnmt1, Dnmt3a and Dnmt3b). …”