The Insulin-Like Growth Factor System in the Long-Lived Naked Mole-Rat by Malene Brohus (840080)

“…They are established contributors to the aging process, confirmed by the demonstration that decreased IGF signaling results in life-extending effects in a variety of species. …”

DataSheet_1_Treatment Interruptions During Stereotactic Body Radiotherapy for Prostate Cancer.docx by Abigail N. Pepin (11966438)

“…Median length of time to complete treatment was 11 days (range 5–155 days). In patients who experienced a delay, nearly half (45.5%) experienced only a one-day delay. …”

Examination of known somatic cell B-Myb target gene expression patterns following knockdown of B-Myb in ESCs. by Ming Zhan (27937)

“…B) RNA (left) and protein (right) analysis of the B-MYB target gene Polo-like kinase 1 (Plk1) following Bγ-Myb KD with shRNA1 and shRNA5. The effects of B-MYB KD on Plk1 RNA were transient; however, the loss of RNA led to a significant and sustained decrease in its protein abundance. …”

Image2_Arnica Montana L. Supercritical Extraction Optimization for Antibiotic and Anticancer Activity.JPEG by Taja Žitek (12521470)

“…The content of proanthocyanidins was highest at a pressure between 18 and 24 MPa. The extracts inhibited three different microorganisms successfully; Staphylococcus aureus, Escherichia coli and Candida albicans, at concentrations ranging from 0.1 to 5.16 mg/ml and showed anticancer activity decrease up to 85% at a concentration of 0.5 mg/ml.…”

Regulation of cardiac transcription factors in liver stem cells co-cultured with cardiomyocytes after minimizing CAMTA1 expression. by Barbara Muller-Borer (159061)

“…The graphs illustrate expression of the transcription factors CAMTA1, CAMTA2, Nk×2.5, Myocardin, cTnT and BetaMHC. A significant decrease in the expression of transcription factors Nkx2.5, Myocardin, cTnT and BetaMHC were measured when CAMTA1 expression was minimized. …”

Image1_Arnica Montana L. Supercritical Extraction Optimization for Antibiotic and Anticancer Activity.JPEG by Taja Žitek (12521470)

“…The content of proanthocyanidins was highest at a pressure between 18 and 24 MPa. The extracts inhibited three different microorganisms successfully; Staphylococcus aureus, Escherichia coli and Candida albicans, at concentrations ranging from 0.1 to 5.16 mg/ml and showed anticancer activity decrease up to 85% at a concentration of 0.5 mg/ml.…”

Evaluation of paralysis time and animal behavior in the open field. by Sunamita de Carvalho Lima (5598089)

“…The last bar in panel A, indicated by the 24 h in the open box, refers to the <i>ip</i> administration of same dose of crotamine (7.5 μg/animal or 0.3 mg/kg BW) in the same animal 24 h after first crotamine administration, showing a significant decrease in the time for paralysis onset compared to the first administration of crotamine in naïve animal, a day before. …”

Systemic status of WT and miR-150 null mutant (miR-150^-/-) mice with normal chow diet or HFD. by Liheng Shi (144105)

“…There is no statistical interaction between miR-150 null mutation and HFD regimen (2-way ANOVA). n = 5 for each group. (C) Wild type mice fed with HFD have a significant decrease of miR-150 expression compared to mice fed with normal diet (Normal; student’s <i>t</i>-test). …”

Conditional knockout of <i>Ezh2</i> gene in murine hearts caused perinatal lethality. by Li Chen (5749)

“…Semi-quantitative RT-PCR with two different numbers of amplification cycles (30 and 35) was performed on RNA samples purified from WT hearts of E9.5, E10.5, and E11.5. 1 µl or 0.5 µl cDNA from reverse transcription reaction was used for detection of Ezh2 or GAPDH (as a control), respectively. …”

hTTR levels in serum and stomach. by Elena Panayiotou (3925415)

“…<p>hTTR immunoblotting exhibiting a single band at 14KDa (<i>A</i>). hTTR levels measured via immunoblotting in serum of V30M and V30M C1q KO animals of all three age groups indicating higher hTTR in the V30M mice and a gradual decrease in the amount of hTTR present as the animals age (<i>B</i>). hTTR levels measured via immunoblotting in stomach tissue of the V30M and V30M C1q KO animals exhibit a severe decrease in the second age group (<i>C</i>). …”

T-helper cell pathway diagram. by Josephine S. D’Alessandro (814578)

“…Gray lines indicate members of a group. APCs, antigen-presenting cells; CXCR1, chemokine (C-X-C motif) receptor 1; CXCR3, chemokine (C-X-C motif) receptor 3; CXCR5, chemokine (C-X-C motif) receptor 5; CXCL10, chemokine (C-X-C motif) ligand 10; GA, glatiramer acetate; HLADMA, major histocompatibility complex class II, DM alpha; HLADMB, major histocompatibility complex class II, DM beta; HLADQB1, major histocompatibility complex class II, DQ beta 1; ICOSLG, inducible T-cell costimulatory ligand; IL-4, interleukin-4; MHC class II, major histocompatibility complex class II; LTB, lymphotoxin beta (tumor necrosis factor superfamily, member 3); MYD, myeloid differentiation primary response protein; S100A10, S100 calcium-binding protein A10; STAT, signal transducer and activator of transcription; TCR, T-cell receptor; Th, T-helper.…”

Effects of Turbulence Intensity and Biogas Composition on the Localized Forced Ignition of Turbulent Mixing Layers by d’Auzay, C. Turquand

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Age-related epigenome-wide DNA methylation and hydroxymethylation in longitudinal mouse blood by Joseph Kochmanski (5597024)

“…We tested the hypothesis that 5hmC changes with age, but in a direction opposite to 5-methylcytosine (5mC), potentially playing a distinct role in aging. …”

Nanoviscosity effect on the spin chemistry of an electron donor/Pt-complex /electron acceptor triad - classical and quantum kinetics interpretation by Stefan Riese (5394071)

“…In pTHF, the magnetic field effect on <i>k</i>_± is a single step function decreasing to its limiting value at about 5 times lower fields than in THF. …”

Data_Sheet_1_Comparative Proteomic Analysis of Grapevine Rootstock in Response to Waterlogging Stress.ZIP by Xicheng Wang (19451)

“…In addition, the MDA and H₂O₂ contents increased after waterlogging treatment, but the chlorophyll a and chlorophyll b contents decreased. A total of 5,578 grapevine proteins were identified by the use of the tandem mass tag (TMT) labeling technique. …”

Hepatitis C Virus Translation Preferentially Depends on Active RNA Replication by Helene Minyi Liu (139939)

“…When the movement of HCV RNA from the site of RNA synthesis to the Golgi complex was blocked by nocodazole, an inhibitor of ER-Golgi transport, HCV protein translation was surprisingly enhanced, suggesting that the translation of viral proteins occurred near the site of RNA synthesis. We also found that the translation of HCV proteins was dependent on active RNA synthesis: inhibition of viral RNA synthesis by an NS5B inhibitor resulted in decreased HCV viral protein synthesis even when the total amount of intracellular HCV RNA remained unchanged. …”

Data_Sheet_2_Trends in the global burden of vision loss among the older adults from 1990 to 2019.DOCX by Jiayang Yin (9273813)

“…YLDs associated with vision loss saw a significant decrease, moving from 1713.5 (95% UI: 1216.2–2339.7) to 1579.1 (95% UI: 1108.3–2168.9, AAPC: −0.12). …”

Data_Sheet_3_Trends in the global burden of vision loss among the older adults from 1990 to 2019.DOCX by Jiayang Yin (9273813)

“…YLDs associated with vision loss saw a significant decrease, moving from 1713.5 (95% UI: 1216.2–2339.7) to 1579.1 (95% UI: 1108.3–2168.9, AAPC: −0.12). …”

Data_Sheet_7_Trends in the global burden of vision loss among the older adults from 1990 to 2019.DOCX by Jiayang Yin (9273813)

“…YLDs associated with vision loss saw a significant decrease, moving from 1713.5 (95% UI: 1216.2–2339.7) to 1579.1 (95% UI: 1108.3–2168.9, AAPC: −0.12). …”

Data_Sheet_4_Trends in the global burden of vision loss among the older adults from 1990 to 2019.DOCX by Jiayang Yin (9273813)

“…YLDs associated with vision loss saw a significant decrease, moving from 1713.5 (95% UI: 1216.2–2339.7) to 1579.1 (95% UI: 1108.3–2168.9, AAPC: −0.12). …”