Fungal DenA developmental functions are independent of Nedd8 processing activity. by Martin Christmann (280300)

“…(E) Human DEN1 cleaved human Nedd8 C-terminally fused with GFP while <i>A. nidulans</i> DenA did not. Nedd8-GFP substrate was combined with decreasing amounts of recombinant DEN1 or DenA, respectively (8–0.5 µM). …”

Personalized Prediction of Lifetime Benefits with Statin Therapy for Asymptomatic Individuals: A Modeling Study by Bart S. Ferket (107294)

“…In 2,428 participants (mean age 67.7 y, 35.5% men), statin therapy increased total life expectancy by 0.3 y (SD 0.2) and CVD-free life expectancy by 0.7 y (SD 0.4). …”

Multinutritional blocks as a food strategy to optimize the use of concentrate for lactating goats by João Paulo de Farias Ramos (5836610)

“…It was evaluated the consumption, milk monitoring and the system was analyzed economically. If there was a significant effect of the concentrate, the control treatment was compared to the others using the Dunnett test and 5% regression analysis. …”

A 67-year-old female patient with Wolff-Parkinson-White syndrome. by Hye-Jeong Lee (467748)

“…Radiofrequency ablation was applied to the posteroseptal accessory pathway through the transseptal approach (asterisk) (A). One year later, the patient underwent cardiac magnetic resonance imaging. …”

Modeled action potentials at successive nodes of Ranvier in a model myelinated axon. by Charles F. Babbs (430220)

“…In this simulation node width was increased three-fold and paranodal resistance was decreased to one tenth the normal value. Average axon diameter 1.0 micrometer; number of nodes of Ranvier 21; normal node width 0.65 micrometer; injured node width 1.95 micrometer; width of juxtaparanodal region on both sides of a node 5.0 micrometers. …”

Cilostazol inhibits endothelin-induced calcium increase and vasoconstriction in mouse intracranial arteries. a. by Yoshifumi Kawanabe (308848)

“…</b> Cilostazol significantly decreases endothelin-induced cytosolic calcium increase. …”

Estimation of some vital trace elements in patients with acute pancreatitis: A case-control study by Falah Al-Fartusie (14344629)

“…This case study was conducted as an attempt to expand our knowledge of the relationship between trace elements and their effect on acute pancreatitis. Sixty-five patients diagnosed with acute pancreatitis with mean age 43.6 years, along with sixty-five healthy volunteers with a mean age 45.7 years, were included in this study. …”

Effect of a High Density of Stacking Faults on the Young’s Modulus of GaAs Nanowires by Yujie Chen (1552645)

“…Stacking faults (SFs) are commonly observed crystalline defects in III–V semiconductor nanowires (NWs) that affect a variety of physical properties. …”

Depletion of hydrocarbons and concomitant shift in bacterial community structure of a diesel-spiked tropical agricultural soil by Oluwafemi Sunday Obayori (9631682)

“…After 21 days (LASTD21), there was a massive enrichment of the phylum <i>Proteobacteria</i> (72.94%), a slight decrease in the abundance of phylum <i>Actinobacteriota</i> (12.74%), and > 500% decrease in the abundance of the phylum <i>Acidobacteriodota</i> (5.26%). …”

An HIV-1 Envelope Immunogen with W427S Mutation in CD4 Binding Site Induced More T Follicular Helper Memory Cells and Reduced Non-Specific Antibody Responses by Hao-Tong Yu (697936)

“…We constructed a gp120 mutant W427S of an HIV-1 primary R5 strain and examined its ability in the elicitation of Ab and the production of Tfh by immunization of BALB/c mice. …”

Expression of nestin (A), GFAP (B) and neurofilament (C) in undifferentiated and differentiated BMSC by Franca Scintu (15221)

“…</p> Untreated cells were labeled for nestin (A1), whose expression decreased with treatment 1 (A2,3) but persisted after treatment 2 (A4). …”

<i>In Silico</i> Identification and <i>In Vitro</i> and <i>In Vivo</i> Validation of Anti-Psychotic Drug Fluspirilene as a Potential CDK2 Inhibitor and a Candidate Anti-Cancer Drug by Xi-Nan Shi (765399)

“…In this study, we utilized our free and open-source protein-ligand docking software, idock, prospectively to identify potential CDK2 inhibitors from 4,311 FDA-approved small molecule drugs using a repurposing strategy and an ensemble docking methodology. …”

Development of a User-Friendly Dynamic Culture System for Decellularized Scaffold-Based Tissue Engineering by Shujuan Fan (8380047)

“…Compared to static controls, constructs cultured in our platform exhibited a > 5-fold increase in proliferating (Ki67+) cells and a 32-fold decrease in apoptotic (TUNEL+) cells. …”

Possible pathways involved in GBE-induced neuroplasticity pathway. by Imane Lejri (8066507)

miR-34a promotes astrocytic differentiation under resveratrol treatment. by Márcia M. Aranha (211052)

“…The blue line corresponds to SIRT1 modulation, while the red line represents the respective control. <b>A.</b> Incubation with nicotinamide, decreased the percentage of GFAP⁺ cells in a dose-dependent manner. …”

SAA in a 50 year-old woman with HHT and severe liver involvement. by Jacques Sellier (8351355)

“…</b> Three enlarged hepatic arteries supply the liver: A 4.5mm middle hepatic artery originating from the coeliac trunk (thin arrow). …”

Comparison between MR and PET in a typical case of left ICA obstruction. by Tetsuya Tsujikawa (2824997)

“…<p><b>a)</b> Comparison between PET-CBF and ASL-CBF. …”

A Caged Electrophilic Probe for Global Analysis of Cysteine Reactivity in Living Cells by Masahiro Abo (716769)

Table 1_Efficacy and safety of sofosbuvir plus daclatasvir in hemodialysis patients with genotype 1b or 2a hepatitis C virus infection: a single-arm, prospective real-world study.x... by Kaili Wang (2246485)

“…Demographic characteristics revealed a mean age of 57.0 years, male predominance (75%), average dialysis duration of 7.0 years, and mean body weight of 63.0 kg. …”

DataSheet1_A focus on CKD reporting and inappropriate prescribing among older patients discharged from geriatric and nephrology units throughout Italy: A nationwide multicenter ret... by Filippo Aucella (821349)

“…Overall, the study population consisted of 2,057 patients, aged 83 (77–89) years, more commonly women, with a median of seven (5–10) drugs prescribed at discharge. …”