SSTR2 IHC. by Estibaliz Castillero (393067)

Saliency maps were employed in order to elucidate which part of the B-scan images the machine learning focused on during training in Model 1. by Taku Toyama (102864)

OCT at 1 month after phacoemulsification. by Jurica Predović (18334274)

PFC elevates microparticles. by Heather F. Pidcoke (9023789)

Cyclization Decoded: Engineering Amylomaltase for Efficient α‑Glucan Transformations by Han Liu (288039)

“…Here, we harness large-scale computations in synergy with biochemical experiments to unravel, at atomic resolution, the full covalent and noncovalent catalytic mechanism of AMs, revealing that cyclization (12.8 kcal/mol) outcompetes hydrolysis (17.5 kcal/mol) as the dominant pathway. Furthermore, we identify that postglycosylation noncovalent polysaccharide chain transfer emerges as the decisive factor in cyclization, particularly for AM–degree of polymerization (DP) greater than 30 substrate complexes, where this noncovalent step (≥13.6 kcal/mol) dictates the rate of CA production. 57 variants with enhanced activity (up to a 2.3-fold increase) were engineered in our biochemical experiments by strategically modulating the chain transfer step. …”

HBV RNA is methylated by NSUN2 in the cell. by Jiangpeng Feng (9287738)

GSK3β is negatively regulated by OPTN during myogenesis. by Xiao Chen Shi (8611887)

Molecular Basis of Calcium-Sensitizing and Desensitizing Mutations of the Human Cardiac Troponin C Regulatory Domain: A Multi-Scale Simulation Study by Peter Michael Kekenes-Huskey (115056)

“…In contrast, site II is very labile for LOF mutants E40A and V79Q in the apo form and bears little resemblance with the holo conformation. …”

S1 Data - by Hao Deng (409186)

“…ERCC1 significantly decreased in processing of CWP. The cutoff value of ERCC1 was 5.265 pg/ml, with a sensitivity of 90.0% and specificity of 86.7%. …”

Change in the genotypes of <i>ATM</i>, <i>ERCC1</i>, and <i>XRCC1</i>. by Hao Deng (409186)

“…ERCC1 significantly decreased in processing of CWP. The cutoff value of ERCC1 was 5.265 pg/ml, with a sensitivity of 90.0% and specificity of 86.7%. …”

Changes in biomarkers with age among past-prime individuals (> 35 years old) in a mixed-longitudinal sample. by Nicole Thompson González (9257300)

Descriptive statistics of the surveys for all data collection years combined. by Diego Montano (4377373)

The knockout strategy of <i>Nsun2</i> in C57BL/6JGpt mice and genotyping strategy. by Jiangpeng Feng (9287738)

Optogenetic stimulation of cultured astrocytes increases the expression of <i>Lcn2</i> and proinflammatory cytokines. by Jae-Hong Kim (124622)

Image_5_Evaluation of the Biodistribution of Mesenchymal Stem Cells in a Pre-clinical Renal Tuberculosis Model by Non-linear Magnetic Response Measurements.TIF by Natalia Yudintceva (10714824)

Image_1_The prevalence of diabetes and thyroid related autoantibodies in Sri Lankan children with type 1 diabetes and their unaffected siblings – The utility of a new screening ass... by Navoda Atapattu (14570081)

“…</p>Results<p>The median age (IQR) of 235 T1D children and 252 unaffected siblings was 11 (8.4, 13.2) and 9 (5.4, 14.9) years respectively, and the duration of T1D was 23 (7, 54) months. (1) T1D children (a) 79.1% were 3-Screen positive; (b) all 3-Screen positives were individual antibody positive (GADA in 74%; IA-2A 31.1%; ZnT8A 38.7%); (c) and were younger (p=0.01 vs 3-Screen negatives); (d) multiple autoantibodies were present in 45.1%; (e) IA-2A (p=0.002) and ZnT8A (p=0.006) prevalence decreased with T1D duration. …”

DataSheet_1_The prevalence of diabetes and thyroid related autoantibodies in Sri Lankan children with type 1 diabetes and their unaffected siblings – The utility of a new screening... by Navoda Atapattu (14570081)

“…</p>Results<p>The median age (IQR) of 235 T1D children and 252 unaffected siblings was 11 (8.4, 13.2) and 9 (5.4, 14.9) years respectively, and the duration of T1D was 23 (7, 54) months. (1) T1D children (a) 79.1% were 3-Screen positive; (b) all 3-Screen positives were individual antibody positive (GADA in 74%; IA-2A 31.1%; ZnT8A 38.7%); (c) and were younger (p=0.01 vs 3-Screen negatives); (d) multiple autoantibodies were present in 45.1%; (e) IA-2A (p=0.002) and ZnT8A (p=0.006) prevalence decreased with T1D duration. …”

OPTN activates canonical Wnt signaling pathway in myoblasts. by Xiao Chen Shi (8611887)

First choice. by Caroline I. Jahn (14522732)

Transmission electron micrographs of expelled <i>Symbiodinium</i> from <i>Acropora selago</i> on the first day at 27°C. by Lisa Fujise (672628)