Defective Resection at DNA Double-Strand Breaks Leads to <em>De Novo</em> Telomere Formation and Enhances Gene Targeting by Woo-Hyun Chung (248941)

“…In <em>sgs1</em>Δ <em>exo1</em>Δ mutants that form only very short ssDNA, allelic gene conversion decreases 5-fold and DSBs are repaired by BIR or <em>de novo</em> telomere formation resulting in loss of heterozygosity. …”

Table_1_Circular RNA Microarray Analyses in Hepatic Ischemia-Reperfusion Injury With Ischemic Preconditioning Prevention.XLS by Xinyao Tian (10268264)

“…Compared with the sham group, there were 39 circRNAs and 432 mRNAs increased and 38 circRNAs and 254 mRNAs decreased (fold change ≥1.5, P < 0.05) in the group of hepatic IRI. …”

Additive Benefits of Control-IQ+ AID to GLP-1 Receptor Agonist Use in Adults with Type 2 Diabetes by Timothy E. Graham (22352054)

“…</p><p dir="ltr">Results: Among GLP1-ra users, mean HbA1c decreased by 0.8% from a baseline of 8.0±1.2% with AID, which represented a mean improvement of -0.5% (95% CI -0.8 to -0.3, p<0.001) compared with the CGM group. …”

Metabolite Profiling Reveals Predictive Biomarkers and the Absence of β‑Methyl Amino‑l‑alanine in Plasma from Individuals Diagnosed with Amyotrophic Lateral Sclerosis by Michael S. Bereman (125416)

“…A support vector machine classifier predicted progression categories with an AUC of 0.90 (0.06) with a mean sensitivity of 73% (10%) and a specificity of 86% (5%). …”

Contribution of <i>hlgABC</i> to USA300 virulence in mouse infection models and survival in human blood. by Natalia Malachowa (224375)

“…(C) Survival of wild-type and Δ<i>hlgABC</i> strains in heparinized human blood. There were 1.5×10⁷ LAC wild-type CFUs at 0 min and this number decreased to 2.4×10⁶ CFUs by 120 min. …”

Impaired cαβT cell development in <i>Rpt</i>^<i>f/f</i><i>-Foxn1Cre</i> mice. by Hong-Xia Wang (288934)

“…</b> Increased death of thymocytes from <i>Rpt</i>^<i>f/f</i><i>-Foxn1Cre</i> mice. Bar graphs represent mean ± SEM of annexin V⁺ cells (<i>n</i> = 5). …”

<i>ELMO1</i> promotes cell migration and invasion by RA FLS. by John W. Whitaker (728679)

“…<p>(<b>A</b>) Cell migration in the wound closure assay shows that <i>ELMO1</i> knockdown with siRNA decreases cell migration whereas the control or ELMO2 siRNAs do not. …”

Inhibition of oligomerization by anti LukS-PV polyclonal antibody. by Hatice Karauzum (320222)

Quantitative analysis <i>in vivo</i> MRI scans. by Lucas W. E. Starmans (379995)

“…<p><i>In vivo</i> T₂ of the thrombus pre- and post-injection with FibPep-ION-Micelles (n = 5) and NCFibPep-ION-Micelles (n = 4). The horizontal lines represent the group means and the average mean for the two groups combined (n = 9). …”

Image_1_Assessment of Epigenetic and Phenotypic Variation in Populus nigra Regenerated via Sequential Regeneration.tif by Weixi Zhang (1626823)

“…We detected a significant difference in methylation levels between first regeneration regenerated plants (G1) and those of the other four generations (G2–G5); there were no significant differences among the four later generations. …”

microRNA-14 as an efficient suppressor to switch off ecdysone production after ecdysis in insects by Kang He (189002)

“…<p>The precise increase and decrease of hormone ecdysone are critical for accurate development in insects. …”

Conditional ablation of <i>Tra2b</i> causes perinatal lethality and disturbed cortical patterning in mice. by Markus Storbeck (191895)

“…Cells of the ventricular and subventricular zones of the cortex show strongest decrease in staining intensity (black arrowhead). Scale bar equals 400 µm; ctx, cortex; th, thalamus; cpt, caudoputamen; cp, cortical plate; iz, intermediate zone; svz, subventricular zone; vz, ventricular zone; sn, septal nuclei; 3v, third ventricle; lv, lateral ventricle; pc, choroid plexus.…”

Local Infusion of Insulin Restores AMPH-Evoked DA Release in Striatum of STZ-Treated Rats by Jason M Williams (61649)

“…<p>Summary data for HSCA (<i>n</i> = 5–7). When measured in the dorsal striatum and compared to saline-treated control subjects, STZ-induced depletion of insulin (STZ) resulted in a significant reduction in the rate of DA efflux in response to local injection of AMPH (400 μM/125 nl; (A) as well as a decrease in the maximum amount of released DA (B) and the rate of DA clearance (C) with respect to control. …”

<i>mecR2</i> is essential for the optimal expression of β-lactam resistance in strains with functional <i>mecI-mecR1</i> regulatory locus. by Pedro Arêde (149569)

“…Note that film was exposed for 4 h whereas in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1002816#ppat-1002816-g005" target="_blank">Figure 5A</a> it was exposed for 48 h.…”

Functional capacity and mental state of patients undergoing cardiac surgery by Bruna Corrêa (4586776)

“…Results: This study assessed nine patients (eight males) aged 62.4 ± 6.3 years with a BMI of 29.5 ± 2.3 kg/m2. There was a significant decrease in DASI scores and VO2 from preoperative to postoperative status (p = 0.003 and p = 0.003, respectively). …”

Changes in Membrane Plasmalogens of <i>Clostridium pasteurianum</i> during Butanol Fermentation as Determined by Lipidomic Analysis by Jan Kolek (712011)

“…When butanol is produced by bacterial cells, then the cells are not subjected to severe stress and responded to it by relatively slowly changing the content of fatty acids and plasmalogens, while after a pulse addition of external butanol (to a final non-lethal concentration of 0.5 % v/v) the cells reacted relatively quickly (within a time span of tens of minutes) by increasing the total plasmalogen content.…”

Association analysis, given linkage, conditional on the top SNP. by Rohina Rubicz (104167)

“…The regression coefficients refer to the estimated change in the phenotype for each dose of the rarer SNP allele.</p>a<p>Since we used a liability threshold model for analysis of the dichotomous trait (see <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003147#s4" target="_blank">methods</a> section), the direction of effect on EBNA-1 discrete serostatus is opposite of the sign of the regression coefficient, but is in the same direction as the regression coefficient for the quantitative trait (e.g. for SNP rs204999, the minor allele is associated with a decrease in EBNA-1 antibody level and seronegativity).…”

The SMART Randomised Controlled Trial by Henrietta Graham (17017581)

“…A small change approach may therefore be an appropriate strategy to reduce the 0.5 to 1 kg of average adult weight gain seen each year and may lead to decreased prevalence of overweight and obesity over time. …”

Ligand Substitutional Effects on Molecular Dynamics and Broadband Near-White Emission in 2D 2‑Fluoroethylammonium Cadmium Chlorobromide by Maciej Ptak (1713061)

“…Optical studies showed that ligand substitution causes narrowing in bandgap energy from 5.12 to 4.28 eV and triggering of white to yellow-green emission thermally quenched above 240 K.…”

Supplementary Material for: Effect of SOM230 (Pasireotide) on Corticotropic Cells: Action in Dogs with Cushing’s Disease by Castillo V. (4126174)

“…SOM230 (pasireotide) is a multiligand somatostatin (SRIF) analog able to bind to somatostatin receptor (SSTR) subtypes 1, 2, 3 and 5, and trigger antisecretory and antiproliferative signaling cascades. …”