Andexanet alfa effectively reverses edoxaban anticoagulation effects and associated bleeding in a rabbit acute hemorrhage model by Genmin Lu (5029949)

“…</p><p>Materials and methods</p><p><i>In vitro</i> studies characterized the interaction of andexanet with edoxaban and its ability to reverse edoxaban-mediated anti-FXa activity. In a rabbit model of surgically induced, acute hemorrhage, animals received edoxaban vehicle+andexanet vehicle (control), edoxaban (1 mg/kg)+andexanet vehicle, edoxaban+andexanet (75 mg, 5-minute infusion, 20 minutes after edoxaban), or edoxaban vehicle+andexanet prior to injury.…”

Structural−Electronic Correlation in the First-Order Phase Transition of [FeH₂L^2-Me](ClO₄)₂ (H₂L^2-Me = Bis[((2-met... by Nicolas Bréfuel (2519947)

“…Variable-temperature magnetic susceptibility measurements show the occurrence of a steep spin crossover centered at 171.5 K with a hysteresis loop of ca. 5 K width ( =174 K and = 169 K, for increasing and decreasing temperatures, respectively). …”

Structure–Activity Relationships and Discovery of (<i>S</i>)‑5‑(<i>tert</i>-Butyl)-11-(difluoromethoxy)-9-methoxy-2-oxo-1,2,5,6-tetrahydropyrido[2′,1′:2,3]imidazo[4,5‑<i>h</i>]quin... by Dimitar Gotchev (1893928)

“…Optimization of a novel series of PAPD5/7 inhibitors that decrease HBsAg levels led to the tetracyclic 2-pyridone <b>AB-161</b>, which was similarly potent to <b>AB-452</b> <i>in vitro</i> and <i>in vivo</i> but showed dramatically higher rodent liver-to-plasma ratios. …”

Effect of Fe and Cd interaction on root and shoot biomass (g). by Babar Hussain (9756385)

<i>elt-2</i> silencing causes decreased intestinal integrity on Bt679 but increased intestinal integrity on Bt247, while pathogen load remains the same as in controls. by Alejandra Zárate-Potes (9415842)

Stay duration (means ± SEM, in minutes) in quinpirole-treated and in saline-treated rats exposed first to elastic and then to symmetrical object-setting (a) and rats exposed first... by Pazit Zadicario (25211)

“…</p><p></p> For each group five times (bars) are shown: the time spent in the spaces between objects (clear bar) and the time at four objects with the longest duration (dark bars; ranked from left to right in decreasing order). * indicates a significant difference between the time spent between the objects (clear bar) and the first-ranked object in each inset (the left dark bar in each inset) as revealed in a Paired t-test comparison in each test group. …”

Do ecological characteristics drive the prevalence of <i>Panulirus argus</i> virus 1 (PaV1) in juvenile Caribbean spiny lobsters in a tropical reef lagoon? by Charlotte E. Davies (8506347)

“…<div><p>PaV1 is a pathogenic virus found only to infect Caribbean spiny lobsters <i>Panulirus argus</i>, a major fishing resource. …”

Fluctuations in airway bacterial communities associated with clinical states and disease stages in cystic fibrosis by Lisa A. Carmody (330117)

“…We sequenced the V3-V5 hypervariable region of the bacterial 16S rRNA gene in DNA derived from 631 sputum specimens collected from 111 CF patients over 10 years. …”

A, Uncropped image of gel in Fig 1B. by Tomokazu Yamaguchi (8284989)

Inhibition of NOX prevented bFGF upregulation of KCNN4 mRNA expression. by Hope K. A. Gole (619718)

PD149163 impairs voluntary locomotion in an open field beginning 10 minutes until at least 120 minutes following injection. by Amanda L. Sharpe (4233751)

Number of bars of length greater than <i>ℓ</i> = 4000 in the barcodes obtained via the binary model (left) and the fuzzy binary model (right) as a function of <i>τ</i>. by Samir Chowdhury (5715338)

Evaporation of Dilute Sodium Dodecyl Sulfate Droplets on a Hydrophobic Substrate by Wojciech Kwieciński (7037669)

“…In contrast to the constant contact angle of an evaporating sessile water droplet, we observed that, at the same surface, the contact angle of an SDS laden droplet with concentration below 0.5 CMC first decreases, then increases, and finally decreases, resulting in a local contact angle minimum. …”

Adsorption characteristics of the carbonaceous adsorbents for organic compounds in a model exhaust gas from thermal treatment processing by Katsuya Kawamoto (12369640)

The impact of chronic kidney disease on developed countries from a health economics perspective: A systematic scoping review by Sarah Elshahat (8587107)

“…Mean EuroQol-5D index scores ranged from 0.80 to 0.86 for CKD stages 1–3, and decreased to 0.73–0.79 for CKD stages 4–5. …”

Data_Sheet_1_Social distancing and changes in drug use: Results from a cross-sectional study during the COVID-19 pandemic in Brazil.pdf by Maurício Schüler Nin (14079738)

Data_Sheet_2_Psychometric validation of a brief self-report measure of misophonia symptoms and functional impairment: The duke-vanderbilt misophonia screening questionnaire.pdf by Zachary J. Williams (8679021)

Data_Sheet_1_Psychometric validation of a brief self-report measure of misophonia symptoms and functional impairment: The duke-vanderbilt misophonia screening questionnaire.docx by Zachary J. Williams (8679021)

Impaired differentiation of alveolar epithelial type I cells in E18.5 <i>Snx5^-/-</i> lungs. by Sun-Kyoung Im (36750)

“…T1α, a marker of alveolar epithelial type I cells, was significantly decreased in <i>Snx5^-/-</i> compared to <i>Snx5^+/+</i> lung (n  =  5). …”

Trends in cutting performance with different chip shapes. by Zhaolong Zhu (5746550)