DataSheet_1_Icanbelimod (CBP-307), a next-generation Sphingosine-1-phosphate receptor modulator, in healthy men: pharmacokinetics, pharmacodynamics, safety, and tolerability in a r... by Jason Lickliter (18073228)

“…After single-dose 0.5 mg, although a high-fat breakfast versus fasting did not affect maximal decrease, lymphocyte counts tended to be lower after breakfast across most timepoints up to 72 hours. …”

Table_2_Head-Down-Tilt Bed Rest With Elevated CO2: Effects of a Pilot Spaceflight Analog on Neural Function and Performance During a Cognitive-Motor Dual Task.docx by Aditya D. Mahadevan (11328372)

“…<p>Spaceflight has widespread effects on human performance, including on the ability to dual task. Here, we examine how a spaceflight analog comprising 30 days of head-down-tilt bed rest (HDBR) combined with 0.5% ambient CO₂ (HDBR + CO₂) influences performance and functional activity of the brain during single and dual tasking of a cognitive and a motor task. …”

Table_1_Head-Down-Tilt Bed Rest With Elevated CO2: Effects of a Pilot Spaceflight Analog on Neural Function and Performance During a Cognitive-Motor Dual Task.DOCX by Aditya D. Mahadevan (11328372)

“…<p>Spaceflight has widespread effects on human performance, including on the ability to dual task. Here, we examine how a spaceflight analog comprising 30 days of head-down-tilt bed rest (HDBR) combined with 0.5% ambient CO₂ (HDBR + CO₂) influences performance and functional activity of the brain during single and dual tasking of a cognitive and a motor task. …”

Image_1_Head-Down-Tilt Bed Rest With Elevated CO2: Effects of a Pilot Spaceflight Analog on Neural Function and Performance During a Cognitive-Motor Dual Task.JPEG by Aditya D. Mahadevan (11328372)

“…<p>Spaceflight has widespread effects on human performance, including on the ability to dual task. Here, we examine how a spaceflight analog comprising 30 days of head-down-tilt bed rest (HDBR) combined with 0.5% ambient CO₂ (HDBR + CO₂) influences performance and functional activity of the brain during single and dual tasking of a cognitive and a motor task. …”

Image_2_Head-Down-Tilt Bed Rest With Elevated CO2: Effects of a Pilot Spaceflight Analog on Neural Function and Performance During a Cognitive-Motor Dual Task.JPEG by Aditya D. Mahadevan (11328372)

“…<p>Spaceflight has widespread effects on human performance, including on the ability to dual task. Here, we examine how a spaceflight analog comprising 30 days of head-down-tilt bed rest (HDBR) combined with 0.5% ambient CO₂ (HDBR + CO₂) influences performance and functional activity of the brain during single and dual tasking of a cognitive and a motor task. …”

AMPK-mTOR-P70S6K signaling cascades are involved in the regulation of CB2R on autophagy both <i>in intro</i> and <i>in vivo</i>. by Ping Ke (3110763)

Data_Sheet_1_DLPFC stimulation alters large-scale brain networks connectivity during a drug cue reactivity task: A tDCS-fMRI study.docx by Ghazaleh Soleimani (13914273)

“…In seed-to-whole brain results, the PFC node in ECN showed an enhanced PPI connectivity with precuneus and visual cortex; the cluster center in MNI (6, –84, –12); the PFC node in DMN showed a decreased PPI connectivity with contralateral parietal cortex;(–48, –60, 46). …”

In vitro and in vivo effects of 2,4 diaminoquinazoline inhibitors of the decapping scavenger enzyme DcpS: Context-specific modulation of SMN transcript levels by Jonathan J. Cherry (501180)

“…Treatment of cells caused modest and transient <i>SMN2</i> mRNA increases with either no change or a decrease in <i>SMNΔ7</i> and no change in <i>SMN1</i> transcripts or SMN protein. …”

Data_Sheet_1_Personalized dietary advices provided by a dietitian increase calcium intake in outpatients with multiple sclerosis—Results from a randomized, controlled, single-blind... by Sandrine Fiorella (14434197)

“…Background and aims<p>Multiple sclerosis (MS) is associated with osteoporosis, possibly due to neurological disability and decreased calcium intake. The objective of this study was to evaluate the efficacy of a personalized nutritional advice program by a dietitian compared to the delivery of a standard advice form to optimize dietary calcium intake in outpatients with MS.…”

X-Linked Alport Dogs Demonstrate Mesangial Filopodial Invasion of the Capillary Tuft as an Early Event in Glomerular Damage by Sabrina D. Clark (3396887)

“…<div><p>Background</p><p>X-linked Alport syndrome (XLAS), caused by mutations in the type IV collagen COL4A5 gene, accounts for approximately 80% of human Alport syndrome. …”

Ocean acidification modulates expression of genes and physiological performance of a marine diatom by Yahe Li (564095)

“…The expression of the genes encoding fucoxanthin chlorophyll <i>a</i>/<i>c</i> protein (lhcf type (<i>fcp</i>)), mitochondrial ATP synthase (<i>mtATP</i>), ribulose-1, 5-bisphosphate carboxylase/oxygenase large subunit gene (<i>rbcl</i>) and NADH dehydrogenase subunit 2 (<i>ndh</i>2), were down-regulated during the first four days (< 8 generations) after the cells were transferred from LC (cells grown under ambient air condition; 390 μatm; pH_nbs 8.19) to OA conditions, with no significant difference between LC and HC treatments with the time elapsed. …”

Dengue seroprevalence in a cohort of schoolchildren and their siblings in Yucatan, Mexico (2015-2016) by Norma Pavía-Ruz (5999918)

“…We included results from 1,844 children aged 0 to 15 years. …”

POSTEROLATERAL, POSTERIOR AND MI-TRANSFORAMINAL LUMBAR INTERBODY FUSION: A STUDY OF 212 CASES by BRUNO MIGUEL BRÍGIDO MAIA (5139194)

Understanding the factors that influence stroke survivors to begin or resume exercise: a qualitative exploration by Helena Drummond (17871887)

Potential effects of mechanically removing macrophytes on the phytoplankton community of a subtropical reservoir by Juliana Wojciechowski (5764874)

Ecosystem services and biodiversity trends in Mozambique as a consequence of land cover change by Sérgio Niquisse (4253536)

hMSCs reduces proliferation of stimulated lymphocytes in a contact-independent manner. by Marilia Normanton (624970)

“…<p>(A–B) A significant proliferation reduction of PHA stimulated lymphocytes (CD3) (38.58±12.39%) assessed by expression of KI-67 was observed in presence of hMSCs (CD3: hMSC) (24.39±12.39%), the same was observed when absolute number KI-67 expressing cells was evaluated decreasing from (3.0×10⁵±1.3×10⁵) up to (1.7×10⁵±0.9×10⁵) (n = 8). …”

Image_1_Can nirmatrelvir/ritonavir treatment shorten the duration of COVID-19 isolation?.pdf by Haein Kim (4839594)

“…Background<p>The impact of nirmatrelvir/ritonavir treatment on shedding of viable virus in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unclear.</p>Methods<p>A prospective cohort study evaluating mildly ill COVID-19 patients was conducted. …”

A comparison of balance control during stance and gait in patients with inflammatory and non-inflammatory polyneuropathy by Oliver Findling (517065)

“…Gait tasks showed a significant decrease in gait speed with respect to HCs for both patient groups but reduced trunk sway for non-inf PNP patients. …”

Understanding the economic impact of leishmaniasis on households in endemic countries: a systematic review by Temmy Sunyoto (610824)