Table_2_Stimulation of the Epithelial Na+ Channel in Renal Principal Cells by Gs-Coupled Designer Receptors Exclusively Activated by Designer Drugs.DOCX by Antonio G. Soares (11328795)

“…The Gs-adenylyl cyclase-cAMP signal transduction pathway is believed to play a central role in the normal control of ENaC activity in PCs. …”

High levels of glucose alter VEGF and miR-200b expression in HRMECs. by Michael Anthony Ruiz (726055)

“…<b>B:</b> Measured by WST-1 assay, HRMECs exposed to increasing concentrations of D-glucose for 24 hours exhibited decreased cell viability at 25mM, 50mM and 100mM compared to 5mM. …”

QRT-PCR for 27-hydroxylase and ABCA1 message in NS398-treated THP-1 macrophages exposed to prostaglandins or TXA by Edwin SL Chan (28334)

“…THP-1 human macrophages were exposed to the following conditions represented by the five bars (from left to right): (1) RPMI 1640, (2) NS398 (50 μM), (3) PGE(0.1 μM) + NS398 (50 μM), (4) PGD(14 μM) + NS398 (50 μM), and (5) TXA(3 μM) + NS398 (50 μM) (24-hour exposures to NS398 alone followed by addition of indicated PG or TXAfor a further 24 hours). …”

Increased secretion of cystatin in response to exercise is transient. by Marcelo de Lima Sant’Anna (7542707)

“…Sprints at 65%, 75% and 85% following first sample are shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0224147#pone.0224147.g004" target="_blank">Fig 4</a>. # indicates a significant increase compared to total protein at rest (<i>pre</i>)(p = 0.012, n = 12). * indicates a significant increase of type-S cystatin at 5 min and § a significant decrease at 10 min compared to resting value (p = 0.012, n = 12). …”

Experimental verification of model predictions. by Mphatso Kalemera (6476033)

“…Scale bar 50μm. We investigated SR-B1 dependence in the over-expressing cells by antibody-mediated receptor blockade (as in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1006905#pcbi.1006905.g002" target="_blank">Fig 2</a>). …”

Time-course of mRNA expression of IGF-system genes and the activation levels of signalling mediators in the E18.8 cochlea. by Hortensia Sanchez-Calderon (186893)

“…<p>(<b>A–D</b>) mRNA expression levels of <i>Igf1</i>, <i>Igf1r</i>, <i>Igfbp2</i> and <i>Igfbp3</i> were analyzed by qRT-PCR in <i>Igf1^+/+</i> (open circles) and <i>Igf1^−/−</i> (closed circles) mice at E15.5 and E18.5 (n = 8), P5, P15, P30, P60 and P90 (n = 6). …”

Table 1_In Vitro biomechanical study of meniscal properties in patients with severe knee osteoarthritis.xlsx by Yuqi Liu (501183)

“…Both tensile and compressive moduli exhibited a stepwise decrease with increasing degeneration. …”

Table 2_In Vitro biomechanical study of meniscal properties in patients with severe knee osteoarthritis.xlsx by Yuqi Liu (501183)

“…Both tensile and compressive moduli exhibited a stepwise decrease with increasing degeneration. …”

Effects of PD-0332991 on BSG cell lines derived from genetically engineered mouse models. by Kelly L. Barton (465812)

“…<p>Cells were treated with PD-0332991 for 48 hours before being harvested for MTT or BrdU assays to assess cell survival and proliferation, respectively. (A) MTT assays (left panel) show minimal cytotoxic activity at doses up to 5µM in cell lines derived from PDGF-B; Ink4a-ARF deficient BSGs. …”

Deletion of <i>Wwox</i> results in defective mammary branching and lobuloalveolar development. by Brent W. Ferguson (167494)

“…<p>(A–B) Representative microphotographs obtained from whole mounts of 12 week virgin <i>BK5 Wwox WT</i> (A) and <i>KO</i> (B) mammary glands. …”

Serial imaging reveals longitudinal dynamics of midgut stem cell lineages. by Leslie Ann Jaramillo Koyama (8363442)

“…Cells were counted at each imaging time point for 8 clones from the 3 animals in A. Between time points, numbers of cells per clone either increased, decreased, or remained constant. …”

Structural, wear and thermal behaviour of Cu–Al2O3–graphite hybrid metal matrix composites by Mittal, P.

“…Copper matrix composites with Al2O3–graphite reinforcement (0.5-0.5, 1.0-1.0, 1.5-1.5 and 2.0-2.0 wt%) were prepared by stir casting process. …”
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Cleavage of BID, loss of MMP, change in expression of anti- and pro-apoptotic proteins. by Radha Pujari (484718)

“…<p>(A) Molt-4 cells were treated with RBL (5 µg/ml) for different time periods and the effect on 21kDa uncleaved Bid was studied by western blot analysis. …”

ICC results of Elk1 and Elk1-3R effects on endogenous katanin-p60 level. by Dolunay Kelle (6388055)

“…(B) Relative fluorescence density graph shows that the expression of katanin-p60 was 5.5 fold decreased in Elk1 overexpressed cells compared to control cells. …”

Summary of anxiogenic and anxiolytic modulation of adult zebrafish behavior in standard 6-min novel tank test (see Fig. S1 in Supplementary Materials for raw data from these experi... by Jonathan Cachat (377024)

“…Statistically significant differences from matched controls (p<0.05, U-test) are represented by solid arrows (empty arrows denote trends; p = 0.05–0.085, U-test): up – increase, down – decrease; empty fields indicate no significant effects, n/a – data not available. …”

Supplementary Material for: Effects of in utero and Postnatal Exposure to Secondhand Smoke on Lung Function by Gender and Asthma Status: The Seven Northeastern Cities (SNEC) Study by Hu L.-W. (3642430)

“…Nonasthmatics had significantly larger deficits from in utero exposure to maternal smoking, which concerned decreased lung FVC function (aOR = 2.58, 95% CI: 1.28-5.21) and decreased lung forced expiratory volume in 1 s (FEV1) function (aOR = 2.32, 95% CI: 1.01-5.33). …”

Impaired Function of CD4+ T Follicular Helper (Tfh) Cells Associated with Hepatocellular Carcinoma Progression by Yiqiong Jia (692871)

“…Importantly, follow-up data indicated that a decreased frequency of circulating CXCR5+CD4+ T cells was also associated with reduced disease-free survival time in HCC patients.…”

Data_Sheet_1_Product Inhibition and pH Affect Stoichiometry and Kinetics of Chain Elongating Microbial Communities in Sequencing Batch Bioreactors.docx by Maximilienne Toetie Allaart (10999293)

“…The process stoichiometries obtained at both pH-values were different: at pH 7.0, 71 ± 6% of the consumed electrons were converted to caproate, compared to only 30 ± 5% at pH 5.5. Operating at pH 5.5 led to a decrease in the biomass yield, but a significant increase in the biomass-specific substrate uptake rate, suggesting that the organisms employ catabolic overcapacity to deal with energy losses associated to product inhibition. …”

Model of EBV latency promoter epigenetic remodeling by GC cytokine driven JAK/STAT signaling. by Yifei Liao (10156956)

“…STAT dimers bind to the C promoter together with a co-repressor to increase levels of repressive 5-methylcytosine (5-mC), H3K9me2/3 and H2AK119Ub epigenetic marks, while decreasing activating H3K27Ac marks. …”

Structure, content and activity of adipose tissues in the Fgl1 null mouse. by Valeriy Demchev (385986)

“…The % uptake represents the uptake of injected dose per gram of tissue. Note the marked decrease in radioisotope uptake in BAT (P = 0.05, n = 5 per group). …”