The association between previous and future severe exacerbations of chronic obstructive pulmonary disease: Updating the literature using robust statistical methodology by Mohsen Sadatsafavi (63962)

“…<div><p>Background</p><p>There is minimal evidence on the extent to which the occurrence of a severe acute exacerbation of COPD that results in hospitalization affects the subsequent disease course. …”

Table_1_Daily Intake of a Phaseolus vulgaris L. Snack Bar Attenuates Hypertriglyceridemia and Improves Lipid Metabolism-Associated Plasma Proteins in Mexican Women: A Randomized Cl... by Aurea K. Ramírez-Jiménez (12750107)

“…A modest body weight (5%) reduction was also found. …”

Core–Shell {Mn₇⊂(Mn,Cd)₁₂} Assembled from Core {Mn₇} Disc by Ling-Yu Guo (3068232)

“…HR-ESI-MS was even more precise by revealing three prominent molecular species, Mn₁₃Cd₆, Mn₁₄Cd₅ and Mn₁₅Cd₄, having a distribution of metals. …”

Genetic Polymorphisms in XRCC1, CD3EAP, PPP1R13L, XPB, XPC, and XPF and the Risk of Chronic Benzene Poisoning in a Chinese Occupational Population by Ping Xue (167911)

“…However, the T allele in PPP1R13L rs1005165 (P<0.05) and the GA allele in CD3EAP rs967591 (OR = 0.162; 95% CI: 0039~0.666; <i>P</i> = 0.037) decreased the risk of CBP in men. The haplotype analysis of XRCC1 indicated that XRCC1 rs25487^A, rs25489^G and rs1799782^T (OR = 15.469; 95% CI: 5.536–43.225; <i>P</i><0.001) were associated with a high risk of CBP.…”

Molecular and functional characterization of a Rho GDP dissociation inhibitor in the filamentous fungus -7 by Michele Menotta (55040)

Efficacy and safety of saxagliptin in combination with insulin in Japanese patients with type 2 diabetes mellitus: a 16-week double-blind randomized controlled trial with a 36-week... by Takashi Kadowaki (35402)

“…</p> <p><b>Research design and methods</b>: We randomized 240 patients with type 2 diabetes mellitus on insulin monotherapy to 5-mg saxagliptin or placebo as add-on therapy for a 16-week, double-blind period. …”

RPIA regulates colon cell proliferation through β-catenin expression in HCT116 cells. by Yu-Ting Chou (447778)

“…<i>AXIN2</i>, <i>Axis inhibition protein 2</i>; <i>CCND1</i>, <i>Cyclin D1</i>; <i>CCNE2</i>, <i>Cyclin E2</i>; <i>CTNNB1</i>, <i>CATENIN BETA 1</i>; pcDNA, pcDNA3 vector control; qPCR, quantitative PCR; RPIA, ribose-5-phosphate isomerase A; si-NC, negative control small interfering RNA; si-RPIA, RPIA small interfering RNA; TCF, T-cell transcription factor.…”

Dynamics and Collapse in a Power System Model with Voltage Variation: The Damping Effect - Fig 4 by Jinpeng Ma (3342755)

“…<p><b>Phase diagrams on the <i>M</i>-<i>P</i></b>_{<b><i>m</i></b>}<b>parameter plane; γ = 0.2 (a) and on the <i>M</i>- γ parameter plane; <i>P</i></b>_{<b><i>m</i></b>}<b>= 0.5 (b) in the third-order power system.…”

An idealized view of the opportunity provided by a comparative and integrated oncology drug development path. by Ira Gordon (369869)

“…Factoring in additional costs for comparative studies with this approach of US$150,000 for studies conducted in the preclinical setting, US$250,000 for studies conducted before or during Phases I–II human trials and US$1 million for studies conducted before Phases II–III studies, the total cost of development is estimated at US$2.07 billion. The result may be a decrease in average clinical trial costs per approved drug from US$290 million to US$173 million <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1000161#pmed.1000161-Adams1" target="_blank">[5]</a>.…”

Temperature-Induced Phase Transitions of Vivianite: In Situ Analysis of a Redox-Driven Crystallization by Alice Paskin (10017280)

Diabetes, Drug Treatment and Mortality in COVID-19: A Multinational Retrospective Cohort Study by Jennifer E. Nyland (11412878)

“…Use of DPP-4 inhibitors was associated with a reduction in respiratory complications (24.0% vs 29.2%; RR, 0.82 [95% CI, 0.74-0.90]; <i>P</i> <.001), and continued use of DPP-4 inhibitors after hospitalization was associated with a decrease in mortality compared with those who discontinued use (9% vs 19%; RR, 0.45 [95% CI, 0.28-0.72]; <i>P</i> <.001). …”

Data_Sheet_1_Expression of vitamin D receptor, CYP24A1, and CYP27B1 in normal and inflamed canine pancreases.DOCX by Dohee Lee (432106)

“…This study showed that VDR expression decreased in inflamed pancreases and demonstrated CYP24A1 and CYP27B1 expression in the canine pancreas for the first time. …”

Application of product development tools in equipment design for a technology-based small business by Felipe Mello Pierobom (10396580)

A simplified methodology for the analysis of the establishment of hydrokinetic parks downstream from hydroelectric plants by Paulo André Vasco Barbosa (5342219)

High mRNA expression of <i>Slc6a15</i> in CNS. by Maria G. A. Hägglund (386708)

Possible pathways involved in GBE-induced neuroplasticity pathway. by Imane Lejri (8066507)

FIGURE 1. Antimicrobial resistance for hospital strains (n=4,375) and study panel (n=180). by Marine Pottier (14099133)

Control of Severe, Life-Threatening External Bleeding in the Out-of-Hospital Setting: A Systematic Review by Nathan P. Charlton (6056651)

TBI causes cell death, mortality, and impaired climbing in a dose-dependent manner. by Bart van Alphen (12003724)

“…(<b>A)</b> 24-hour survival rate decreased with increased number of strikes. …”

Altered adaptive responses to a novel environment in <i>Slitrk6</i>-KO mice. by Yoshifumi Matsumoto (257936)

“…<p>(A, B) Open field test. (A) The total distance moved was less in <i>Slitrk6</i>-KO than in WT mice (left). …”