Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization by Kun Liu (148201)

“…To assess the effects of decreased macrophage autophagy on inflammation, mice with a <i>Lyz2</i>-<i>Cre</i>-mediated knockout of <i>Atg5</i> in macrophages were fed a HFD and treated with low-dose lipopolysaccharide (LPS). …”

Image_1_Production of Triple-Gene (GGTA1, B2M and CIITA)-Modified Donor Pigs for Xenotransplantation.tif by Kaixiang Xu (4571833)

“…Phenotyping data showed that the mRNA expressions of triple genes and protein expressions of B2M and CIITA genes were still detectable and comparable with wild-type (WT) pigs in multiple tissues, but α1,3-galactosyltransferase was eliminated, SLA-I was significantly decreased, and four subtypes of SLA-II were absent in GBC-modified pigs. …”

Table_1_Production of Triple-Gene (GGTA1, B2M and CIITA)-Modified Donor Pigs for Xenotransplantation.docx by Kaixiang Xu (4571833)

“…Phenotyping data showed that the mRNA expressions of triple genes and protein expressions of B2M and CIITA genes were still detectable and comparable with wild-type (WT) pigs in multiple tissues, but α1,3-galactosyltransferase was eliminated, SLA-I was significantly decreased, and four subtypes of SLA-II were absent in GBC-modified pigs. …”

Table_2_Production of Triple-Gene (GGTA1, B2M and CIITA)-Modified Donor Pigs for Xenotransplantation.docx by Kaixiang Xu (4571833)

“…Phenotyping data showed that the mRNA expressions of triple genes and protein expressions of B2M and CIITA genes were still detectable and comparable with wild-type (WT) pigs in multiple tissues, but α1,3-galactosyltransferase was eliminated, SLA-I was significantly decreased, and four subtypes of SLA-II were absent in GBC-modified pigs. …”

Image_2_Production of Triple-Gene (GGTA1, B2M and CIITA)-Modified Donor Pigs for Xenotransplantation.tif by Kaixiang Xu (4571833)

“…Phenotyping data showed that the mRNA expressions of triple genes and protein expressions of B2M and CIITA genes were still detectable and comparable with wild-type (WT) pigs in multiple tissues, but α1,3-galactosyltransferase was eliminated, SLA-I was significantly decreased, and four subtypes of SLA-II were absent in GBC-modified pigs. …”

Roles of varying protein and choline nutrient contents in very high fat, low protein, very low carbohydrate diet-induced hepatic steatosis. by Rebecca C. Schugar (452038)

“…Data are presented as means±SEM. <i>a</i>, significant difference compared to chow; <i>b</i>, significant difference attributable to decrease in protein content (from 10% kcal to 5% kcal) at a fixed choline content; <i>c</i>, significant difference attributable to restriction in choline content (from 5.3 g/kg to 0.3 g/kg) at a fixed protein content; by 1-way ANOVA with Tukey’s post hoc testing.…”

Cdk1 inhibition reproduces the loss of FlnB phenotypes. by Jianjun Hu (19574)

“…(B) Flow cytometry following propridium iodide (PI) labeling shows a decrease in the number of ATDC5 cells in G2/M phase and an increase in the number of ATDC5 cells in G1/G0 phase in the Cdk1 inhibitor (1 µM) treated cells compared to control. …”

Assessment of oscillatory potential (OP) amplitude profiles. by Jake Bedore (777372)

“…Quantification of summed OP amplitude for the four OPs measured over the four largest stimulus strengths (0.63–25 cd˖s /m²) under scotopic conditions measured shows a significant decrease in VAChT^{Six3-Cre-flox/flox} retinas (open circles) relative to littermate controls (VAChT^flox/flox, closed squares) at (I) 5 (n = 7 VAChT^{Six3-Cre-flox/flox} and n = 12 littermate control) and (J) 12 months of age (n = 5 VAChT^{Six3-Cre-flox/flox} and n = 5 littermate control). …”

Effects of site-specific sustained photostimulation of inhibitory neurons within the pre-Bötzinger complex <i>in situ</i>. by Jessica Ausborn (5147210)

“…(<b>D</b>) Summary data (n = 10, mean ± SEM, **p<0.01, *p<0.05) of bilateral pre-BötC photostimulation shows that relatively weak (0.5–2.0 mW) stimulation significantly increased respiratory frequency in a laser power-dependent manner, and stronger (4.0–5.0 mW) stimulation caused a decrease of inspiratory frequency with complete termination of inspiratory activity for the stimulus duration at the maximum laser power (5.0 mW).…”

Table_2_Lung Function After Stereotactic Body Radiation Therapy for Early-Stage Non-Small Cell Lung Cancer, Changes and Predictive Markers.xlsx by Janna Berg (5515091)

“…FEV1 and DLCO in percent decrease 7-8% at 1-1.5 months in the symptomatic radiation pneumonitis group. …”

Table_1_Lung Function After Stereotactic Body Radiation Therapy for Early-Stage Non-Small Cell Lung Cancer, Changes and Predictive Markers.docx by Janna Berg (5515091)

“…FEV1 and DLCO in percent decrease 7-8% at 1-1.5 months in the symptomatic radiation pneumonitis group. …”

Comparative sensitivity of the test with tuberculosis recombinant allergen, containing ESAT6-CFP10 protein, and Mantoux test with 2 TU PPD-L in newly diagnosed tuberculosis childre... by Liudmila Slogotskaya (6111866)

“…</p><p>Conclusion</p><p>In children and adolescents with active tuberculosis, Diaskintest of 0.2 μg/ml and the Mantoux test with 2 TU PPD-L have high sensitivity (98%) at a cut-off of 5 mm; however, at cut-off ≥ 15 mm sensitivity is significantly reduced, and the decrease is more pronounced in the Mantoux test. …”

Table_3_Lung Function After Stereotactic Body Radiation Therapy for Early-Stage Non-Small Cell Lung Cancer, Changes and Predictive Markers.xlsx by Janna Berg (5515091)

“…FEV1 and DLCO in percent decrease 7-8% at 1-1.5 months in the symptomatic radiation pneumonitis group. …”

Figure S1 - Histological and Functional Benefit Following Transplantation of Motor Neuron Progenitors to the Injured Rat Spinal Cord by Sharyn L. Rossi (244876)

“…There was a 5-fold decrease in NGF expression in hMNP when compared to hFibs (b) Western blot analysis confirming that hMNP express and secerete NT-3, NT-4, NGF, and VEGF.…”

Figure S1 - Histological and Functional Benefit Following Transplantation of Motor Neuron Progenitors to the Injured Rat Spinal Cord by Sharyn L. Rossi (244876)

“…There was a 5-fold decrease in NGF expression in hMNP when compared to hFibs (b) Western blot analysis confirming that hMNP express and secerete NT-3, NT-4, NGF, and VEGF.…”

G295S mutation in <i>Gata4</i> results in cardiomyocyte proliferation defects. by Chaitali Misra (165517)

“…<p>Immunofluorescent staining for phosphohistone H3 (red) along with desmin staining for cardiomyocytes (green) demonstrates decreased cardiomyocyte proliferation in <i>Gata4 G295S^ki/ki</i> (B) as compared to wildtype (A) in histologic sections of E9.5 hearts. …”

Foxm1 expression during heart development. by Craig Bolte (299486)

“…Mean±SEM was determined from 5 random sections at E14.5 and P7 with 3 hearts in each group. qRT-PCR of total heart RNA demonstrated a decrease in Foxm1 mRNA from E14.5 to P20 and Foxm1 mRNA was undetectable in the adult heart (R). …”

Adhesion inhibition by BJ treatment. by Simona Delle Monache (402973)

“…<p>(A) Representative images showing the decreased adhesive capacity of SH-SY5Y cells following 2 hs of BJ treatment. …”

Kinetic profile of PIU. by Nadav Ben-Dov (167666)

“…Rate was determined by introducing Dextran-FITC as a short pulse for the last 10 min of the cells’ exposure to pH 5.25. …”

DNA condensation profile of poly APS and LipoGen using different DNA; pEGFP (4 by Debra McLaggan (14660)

“…Ethidium bromide assay shows a decrease of fluorescence intensity (excitation at 260 nm, and emission at 600 nm) when poly-APS (A) or LipoGen (B) concentration was increased, expressed in a mole ratio of ammonium/DNA phosphate (N/P). …”