Image1_Total flavonoids extracted from Penthorum chinense Pursh mitigates CCl4-induced hepatic fibrosis in rats via inactivation of TLR4-MyD88-mediated NF-κB pathways and regulatio... by Sujuan Wang (1865149)

“…Subsequently, rats were randomly assigned to a control group (Control), a carbon tetrachloride (CCl₄)-induced hepatic fibrosis model group (Model), a positive control group [0.2 mg/(kg∙day)] of Colchicine), and three TFPCP treatment groups [50, 100, and 150 mg/(kg∙day)]. …”

Image2_Total flavonoids extracted from Penthorum chinense Pursh mitigates CCl4-induced hepatic fibrosis in rats via inactivation of TLR4-MyD88-mediated NF-κB pathways and regulatio... by Sujuan Wang (1865149)

“…Subsequently, rats were randomly assigned to a control group (Control), a carbon tetrachloride (CCl₄)-induced hepatic fibrosis model group (Model), a positive control group [0.2 mg/(kg∙day)] of Colchicine), and three TFPCP treatment groups [50, 100, and 150 mg/(kg∙day)]. …”

Image_1_Archetypal type II and III Toxoplasma gondii oocysts induce different immune responses and clinical outcomes in experimentally infected piglets.tif by Andrea Largo-de la Torre (13985607)

“…Apathy and a moderate decrease in feed consumption were observed in G1 and G2 piglets between 5 and 8 dpi, coinciding with fever (>40°C). …”

Kinetics of T and DHT and their predicted effects on prostatic gene occupancy. by Michael G. Zager (138879)

“…(Middle right panel) Prostatic DHT concentrations are decreased due to dropping levels of blood DHT and prostatic 5aR2 inhibition. …”

Scavenging of reactive oxygen species suppresses maize penetration resistance to the <i>Δpep1</i> mutant. by Christoph Hemetsberger (166544)

“…A papilla is formed at the point of penetration (arrow). (<b>B</b>) SG200Δpep1RFP penetrating the maize epidermis of plants treated with 5 µM ascorbate. …”

ABT-737 induces ER stress and cell death in melanoma cells. by Karianne Risberg (207221)

“…<p>(A) Increased GRP78 and peIF2α protein levels in FEMX, Melmet-5 and MelRM melanoma cells treated with ABT-737 (10 µM) up to 48 h, indicating ER stress. …”

Peroxide-induced perturbations to peptide metabolism. by Carlo Giannangelo (8053910)

“…<p><b>a</b>, Heatmap showing the average fold change for all identified peptides at each time point after treatment of trophozoite-infected cultures (<i>P</i>. …”

Aborted oceanic basin during the Mesozoic rifting of the South-Iberian Palaeomargin and interactions with the sedimentation processes by Matías Reolid (4318252)

“…Values of some ratios such as (Gd/Yb)_N, (La/Yb)_N, (La/Sm)_N, and the Nb content increase in the Upper Cretaceous pillow-lava flows, whereas Yb and Y contents decrease, that point to more alkaline affinity. Low Yb and Y contents point to the presence of garnet as residual phase in the mantle source. …”

Characterization of changes in Ecrg4 gene expression in ME mucosal after NTHi infection. by Arwa Kurabi (344167)

“…The decrease was compared to the thickness of the ME mucosa (dashed line). …”

A: <i>In vitro</i> immunomodulatory effect of HD-MSCs and ALL-MSCs on HD-PBMCs. by Antonella Conforti (481227)

“…<p>The graph shows the proliferation of healthy donor peripheral blood mononuclear cells (HD-PBMCs) stimulated with phytohemagglutinin (PHA) either in the presence or in the absence of HD-MSCs or ALL-MSCs, generated at disease onset and subsequent time-points of treatment (day+15; day+33; day+78). Each bar represents the percentage of proliferation of 10⁵ PBMCs, in the presence of two different MSC∶PBMC ratios (MSC∶PBMC ratio of 1∶2 and 1∶10), calculated by measuring ³H-thymidine incorporation after 3-day co-culture. …”

Temporal changes in mitochondrial density and structure in response to Myc. by J. Anthony Graves (164485)

cbVG-dependent SGs are not required for the antiviral response during RSV cbVG-high infection. by Lavinia J. González Aparicio (17420047)

“…<p>mRNA copy numbers of (<b>A</b>) <i>IL29</i>, (<b>B</b>) <i>ISG56</i>, and (<b>C</b>) <i>IRF7</i> relative to the HKI in A549 control, G3BP1 KO, G3BP2 KO, and G3BP1/2 dKO cells 24 hpi with RSV cbVG-high at MOI 1.5 TCID₅₀/cell. …”

Modulation of AChR and GABA_R can restore post-synaptic folding. by M. Catarina Silva (189975)

“…(B) L-AChR activation with the agonist levamisole (in water) suppressed Q35 aggregation at 5 µM, but enhanced aggregation at 50 µM. Mutant AChR <i>unc-38(e264)</i> is a control for AChR-mediated effect. …”

Prostaglandin E2 potentiation of P2X3 receptor mediated currents in dorsal root ganglion neurons-5 by Congying Wang (81505)

“…</p><p></p>β-meATP (1 nmol/50 μl) or PGE2 ((0.05 nmol/50 μl). The data were normalized with baseline responses before either injection. α,β-meATP and PGE2 applied individually resulted in a moderate decrease in the threshold [(1-meATP/Con) = 0.22 ± 0.04; (1-PGE/Con) = 0.16 ± 0.03, n = 3)]. …”

No inhibition of TrxR1 activity <i>in vitro</i> by addition of SecTRAPs by Karin Anestål (377878)

“…The turnover (min⁻¹) is calculated from the decrease at 340 nm detected in a microplate reader assay using 5 nM TrxR1, 145 µM insulin in 50 mM Tris-Cl, 2 mM EDTA, pH 7.4 and 200 µM NADPH.…”

Dopamine depletion increases intrinsic excitability of medium spiny neurons. by Karima Azdad (370732)

GDF11 inhibits Cyclin D2 expression. by Gareth Williams (5148)

“…(<b>B</b>) Densitometric analysis of western blots of lysates from Cor-1 cells treated with 25 or 50 ng/ml of GDF11 for 24 hr shows a significant decrease in Cyclin D2 protein levels (mean ± SEM; **<i>p</i><0.01, n = 3). …”

PDTC inhibits the <i>Nacrein</i> promoter activity. by Juan Sun (439334)

“…Increasing amounts of PDTC lead to a decrease in luciferase activity, suggesting a decrease in <i>Nacrein</i> promoter activity. …”

Proportions of female contact initiations towards her partner (being kept isolated marked by 0 - line) or in relation to the total number of contact initiations by both sexes in th... by Herbert Hoi (295931)

Effects (mean ln R and 95% CI) of live, dead, artificial crab spiders (model), past predation events (PPE) and objects that do no resemble predators on pollinator visitation rate o... by Gustavo Q. Romero (217663)