The Effect of Aerobic Exercise on Intrahepatocellular and Intramyocellular Lipids in Healthy Subjects by Andrea Egger (107540)

“…Two hours aerobic exercise resulted in a significant decrease in IMCL (−22.6±3.3, % from baseline) and increase in IHCL (+34.9±7.6, % from baseline). …”

Generation of post-mitotic neurons requires NRG1-II. by Tomomi Sato (301255)

“…<i>4neurog1</i>:<i>nRFP</i>) at 50 hpf. Scale bar, 10 μm. <b>C</b>. Quantification of <i>neurod</i>:EGFP intensity in the OT for the experiment shown in A (mean ± s.e.m.; **<i>P</i> < 0.01; n = 4 per group). …”

Characterizing suboptimal child passenger safety practices in crashes with fatalities: Child, driver, vehicle, neighborhood, and policy factors by Arthi S. Kozhumam (14176683)

“…We sought to identify child, driver, vehicle, neighborhood, and policy-level factors associated with suboptimal child passenger safety practices in motor vehicle collisions (MVCs) with a fatality. …”

Responses to growth factors. by Kazunari Mouri (265029)

Quantitative analysis of the collagen fibers in the subcutaneous pancreatic tumor xenografts. by Wenyan Hu (162244)

“…<p>(A) The collagen density decreases as the tumor xenografts grow. …”

Smad1 target genes repressed and activated in senescence. by Atsushi Kaneda (198186)

“…<p>(<i>A</i>) Repression of Smad1 target genes by H3K27me3. 838 Smad1 target genes in MEF were sorted by fold expression change between MEFp2 and mean of RasV12 day3, 7, and 10 (<i>Expression column</i>). 50 genes showed increase of H3K27me3 reads in RasV12 by 0.4 or more (↑<i>column</i>), and were significantly enriched downward (*P = 0.004, Kolmogorov-Smirnov test), i.e. repressed. …”

Video1_The mechanisms of potassium loss in acute myocardial ischemia: New insights from computational simulations.AVI by Jose M. Ferrero (6705797)

“…In order to investigate these mechanisms, we developed a novel computational model of acute myocardial ischemia which couples a) an electrophysiologically detailed human cardiomyocyte model that incorporates modifications to account for ischemia-induced changes in transmembrane currents, with b) a model of cardiac tissue and extracellular K⁺ transport. …”

DataSheet1_The mechanisms of potassium loss in acute myocardial ischemia: New insights from computational simulations.docx by Jose M. Ferrero (6705797)

“…In order to investigate these mechanisms, we developed a novel computational model of acute myocardial ischemia which couples a) an electrophysiologically detailed human cardiomyocyte model that incorporates modifications to account for ischemia-induced changes in transmembrane currents, with b) a model of cardiac tissue and extracellular K⁺ transport. …”

Image_1_Modulation of low-dose ozone and LPS exposed acute mouse lung inflammation by IF1 mediated ATP hydrolysis inhibitor, BTB06584.tif by Pahul Singh (14781409)

“…Ozone and LPS exposure induced lung neutrophil and eosinophil recruitment as measured by respective peroxidase (MPO and EPX) assays, systemic leukopenia, increased levels of lung vascular neutrophil regulatory chemokines such as CXCL5, SDF-1, CXCL13 and a decrease in immune-regulatory chemokines such as BAL IL-10 and CCL27. …”

Image_2_Modulation of low-dose ozone and LPS exposed acute mouse lung inflammation by IF1 mediated ATP hydrolysis inhibitor, BTB06584.tif by Pahul Singh (14781409)

“…Ozone and LPS exposure induced lung neutrophil and eosinophil recruitment as measured by respective peroxidase (MPO and EPX) assays, systemic leukopenia, increased levels of lung vascular neutrophil regulatory chemokines such as CXCL5, SDF-1, CXCL13 and a decrease in immune-regulatory chemokines such as BAL IL-10 and CCL27. …”

Image_3_Modulation of low-dose ozone and LPS exposed acute mouse lung inflammation by IF1 mediated ATP hydrolysis inhibitor, BTB06584.tif by Pahul Singh (14781409)

“…Ozone and LPS exposure induced lung neutrophil and eosinophil recruitment as measured by respective peroxidase (MPO and EPX) assays, systemic leukopenia, increased levels of lung vascular neutrophil regulatory chemokines such as CXCL5, SDF-1, CXCL13 and a decrease in immune-regulatory chemokines such as BAL IL-10 and CCL27. …”

Gas exchange response to exercise in two SSc patients. by Daniel Dumitrescu (329168)

“…Arrow 2 points to the <i>AT</i> in panel 5 (branch-point 2). …”

<i>In-silico</i> identification of fingerprint of pyrazolyl sulfonamide responsible for inhibition of <i>N</i>-myristoyltransferase using Monte Carlo method with index of ideality... by Ashwani Kumar (55732)

“…The mechanistic interpretation of developed models explains the role of different structural attributes in predicting the pIC₅₀ of pyrazole sulfonamides extracted from the crystal structure of Leishmania major N-myristoyltransferase (NMT) along with co-crystallized myristoyl-CoA and ligands NMT106, NMT157, NMT187 and NMT236 (PDB ID: 4A2Z, 4A30, 4A32, 2WSA). …”

The Protein <i>O</i>-glucosyltransferase Rumi Modifies Eyes Shut to Promote Rhabdomere Separation in <i>Drosophila</i> by Amanda R. Haltom (664189)

“…The intracellular accumulation of Eys and the IRS defect worsen in <i>rumi</i> mutants raised at a higher temperature, and are accompanied by a ∼50% decrease in the total level of Eys. …”

Presentation_1_Dysfunctional LAT2 Amino Acid Transporter Is Associated With Cataract in Mouse and Humans.pdf by Emilia Boiadjieva Knöpfel (6795341)

“…We show that neutral amino acid antiporter LAT2 (Slc7a8) and uniporter TAT1 (Slc16a10) are expressed on mouse ciliary epithelium and LAT2 also in lens epithelium. …”

Table_1_An optimized Factor H-Fc fusion protein against multidrug-resistant Neisseria gonorrhoeae.docx by Jutamas Shaughnessy (166043)

“…Although both molecules bound gonococci similarly, Fc1/FH* displayed a 5-fold lower IC50 (the concentration required for 50% killing in complement-dependent bactericidal assays) than FH*/Fc1. …”

The strength of the signal at binding sites depends on the free energy of repressor binding. by Rosalind Wenshan Pan (17174817)

“…Δ<i>ε</i>_pd is fixed at -5 <i>k</i>_<i>B</i><i>T</i>, RNAP copy number is fixed at 1000, and repressor copy number is fixed at 10. …”

KRIT1 regulates steady-state levels of intracellular ROS. by Luca Goitre (245127)

“…Notice that KRIT1^−/− cells displayed the highest content of intracellular ROS, whereas the re-expression of KRIT1 caused a significant, expression level-dependent decrease in intracellular ROS levels.…”

Hebbian properties emerge through the interaction of selective input and homeostatic control. by Júlia V. Gallinaro (11682139)

Mechanisms involved in Sag-induced apoptosis. by Juliana Mundiñano (306020)