Reduced skin lipid content in obese Japanese women mediated by decreased expression of rate-limiting lipogenic enzymes by Yoshiko Horie (4923043)

“…Both skin cholesterol and fatty acid levels exhibited an “inverted-U” relationship with BMI, suggesting that there is an optimal BMI for peak lipid content and barrier function. Decreased lipid levels at higher BMI were accompanied by downregulated expression of <i>PPARδ</i> and other genes related to lipid metabolism, including those encoding acetyl-CoA carboxylase and HMG-CoA reductase, the rate-limiting enzymes for fatty acid and cholesterol synthesis, respectively. …”

The ketogenic diet causes a significant decrease in insulin, but does not affect the PI3K pathway. by Mai T. Dang (772520)

Most acute brain lesions in the white matter (Aa, Ba) showed a decrease in size and/or faded. by Su-Hyun Kim (573826)

Table 5_Temporal and spatial trends in gastric cancer burden in the USA from 1990 to 2021: findings from the global burden of disease study 2021.xlsx by Chengwei Zhan (18872651)

Despair by age UK, UKHLS, 2009–2021. by David G. Blanchflower (8011427)

Distribution of donated shares across treatments (%). by Pablo Brañas-Garza (336425)

Histograms showing ranks of selected metrics. by Thomas Hopper (3216453)

T37A mutation protects M1 protein of BJ/3/99 virus from degradation directed by PKG and increases the viral replication. by Chenxi Wang (284364)

Demographic characteristics of 50 DENV-2 viremic feedings evaluated for infectiousness to <i>Aedes aegypti</i> mosquitoes. by Louis Lambrechts (241741)

Injury-induced cold sensitization in <i>Drosophila</i> larvae involves behavioral shifts that require the TRP channel Brv1 by Heather N. Turner (6157268)

Large amounts of ingested phenylpyruvate are required to decrease the survival of adult <i>A. gambiae</i> mosquitoes. by Silke Fuchs (506300)

Lowering Melting Points in Asymmetrically Substituted Salen-Copper(II) Complexes Exhibiting Mesomorphic Behavior. Structure of the Mesogen Cu(5-hexyloxySalen) by Reinhard Paschke (553784)

“…In comparison with their symmetrical analogues, unsymmetrically substituted Cu−Salen complexes show mesophases with lowered melting points. For terminally substituted complexes, symmetrical ones (R¹ = R²) have only an S_A phase, while for unsymmetrical alkoxy substitution a monotropic S_E phase occurs and the melting temperature decreases with no loss in mesophase stability. …”

Lowering Melting Points in Asymmetrically Substituted Salen-Copper(II) Complexes Exhibiting Mesomorphic Behavior. Structure of the Mesogen Cu(5-hexyloxySalen) by Reinhard Paschke (553784)

“…In comparison with their symmetrical analogues, unsymmetrically substituted Cu−Salen complexes show mesophases with lowered melting points. For terminally substituted complexes, symmetrical ones (R¹ = R²) have only an S_A phase, while for unsymmetrical alkoxy substitution a monotropic S_E phase occurs and the melting temperature decreases with no loss in mesophase stability. …”

Growth kinetics of Measles viruses in Vero and THP-1 cell lines. by Pierre Khalfi (7868252)

2‑Aminobenzoxazole Derivatives as Potent Inhibitors of the Sphingosine-1-Phosphate Transporter Spinster Homolog 2 (Spns2) by Ariel L. Burgio (15069256)

“…To develop more potent compounds, we initiated a structure–activity relationship study that identified 2-aminobenzoxazole as a viable scaffold. …”

<i>Otx</i> knockdown causes a decrease in <i>dct</i> expression in the developing RPE. by Brandon M. Lane (123574)

“…<i>dct</i> expression was reduced only in the ventral most region of the optic cup in single morphants (B–D, white arrows) compared to controls (A). <i>dct</i> expression was significantly decreased in the ventral RPE of <i>otx1a</i>/<i>otx2</i> morphants and to an even greater degree in <i>otx1a</i>/<i>otx1b</i>/<i>otx2</i> morphants (E–F, white arrows). …”

Raw database. by Franco Romaní-Romaní (21989788)

“…This study aimed to evaluate longitudinal trends in PT scores at a Peruvian medical school.</p><p>Methods</p><p>We conducted a longitudinal analysis using data from PTs administered annually between 2017 and 2024. …”

Glutathione metabolism decreases during infection with <i>P</i>. <i>aeruginosa</i> in a FadE2-dependent manner. by Siraje Arif Mahmud (3188391)

Recombination of Autodissociated Water Ions in a Nanoscale Pure Water Droplet by Soonho Kwon (1402972)

“…We found that the self-diffusion of water dramatically decreases in droplets with a diameter below 2.2 nm. …”

Recombination of Autodissociated Water Ions in a Nanoscale Pure Water Droplet by Soonho Kwon (1402972)

“…We found that the self-diffusion of water dramatically decreases in droplets with a diameter below 2.2 nm. …”