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341
Hippocampal Programmed Cell Death after Status Epilepticus
Published 2003“…To investigate potential mechanisms that may underlie SE-related neuronal injury, we studied the occurrence of programmed cell death (PCD) in the hippocampus in the kainic acid (KA) model. …”
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342
A Multidecadal Assessment of Haze Development and Fluctuations in Visibility for Arabian Peninsula
Published 2024“…To comprehend the time-based patterns of visibility across the ME, we utilized the Mann Kendall (MK) and Modified Mann Kendall (MMK) trend estimators in both space and time. …”
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343
Acute intense fatigue does not modify the effect of EVA and TPU custom foot orthoses on running mechanics, running economy and perceived comfort
Published 2022“…Immediately after completion of a repeated-sprints exercise (8 × 5 s treadmill sprints, rest = 25 s), these run tests were replicated. …”
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344
Global time differences in road traffic injuries among children and adolescents between and 1990 and 2013: Regional and economical perspectives from global burden of diseases study
Published 2015“…Mortality rates for VRUs and nVRUs also decreased remarkably except among non-VRUs from LICs where the mortality rates increased by 16%. …”
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345
Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function
Published 2024“…In cardiac muscle, CaM modulates directly or indirectly the activity of several proteins that play a key role in excitation‐contraction coupling (ECC), such as ryanodine receptor type 2 (RyR2), l‐type Ca<sup>2+</sup> (Ca<sub>v</sub>1.2), sodium (NaV1.5) and potassium (KV7.1) channels. …”
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346
How global spine sagittal alignment and spinal degeneration affect locomotive syndrome risk in the elderly
Published 2024“…Except for L1–L2 and L5–S1, lumbar disc height (LDH) decreased with higher LS risk stages. …”
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347
Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for th...
Published 2020“…Age-standardised prevalence of avoidable blindness decreased by −15·4% [–16·8 to −14·3], while avoidable MSVI showed no change (0·5% [–0·8 to 1·6]). …”
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348
Vitamin D Association With Macrophage-Derived Cytokines in Polycystic Ovary Syndrome: An Enhanced Risk of COVID-19 Infection?
Published 2021“…Basal macrophage activation markers CXCL5, CD163 and MMP9 were elevated, whilst protective CD200 was decreased (p<0.05); changes in these variables were related to, and fully accounted for, by BMI. …”
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349
Heat Shock-Related Protein Responses and Inflammatory Protein Changes Are Associated with Mild Prolonged Hypoglycemia
Published 2021“…At hypoglycemia, UBE2N, STIP1, and UBE2L3 increased (all p < 0.05), whilst TLR4:MD-2 and HSPA8 decreased (p < 0.05) in T2D versus baseline. In follow-up after hypoglycemia, HSPs normalized to baseline by 24 h, except UBE2L3 (p < 0.05), which was decreased in controls versus baseline. …”
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350
Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis
Published 2025“…As LAT2 was previously found to be highly expressed in skeletal muscle, here we characterised its role in the regulation of <i>skeletal muscle</i> amino acid flux and metabolic adaptation to fasting.…”
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351
Resveratrol-Elicited PKC Inhibition Counteracts NOX-Mediated Endothelial to Mesenchymal Transition in Human Retinal Endothelial Cells Exposed to High Glucose
Published 2021“…Primary Human Retinal Endothelial Cells (HRECs) were either pre-treated for 24 h with 1 µM resveratrol or left untreated, then glucose (30 mM) was applied at 3-day intervals for 10 days. qRT-PCR and ELISA were used to detect mRNA or protein expression of endothelial markers (CD31, CDH5, vWF) or mesenchymal markers (VIM, αSMA and collagen I), respectively. …”
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352
Prevalence of bullying and violence among adolescents in Arab Gulf countries: a systematic review
Published 2025“…</p><h3 dir="ltr">Subject and methods</h3><p dir="ltr">We conducted a comprehensive search across PubMed, EMBASE, Scopus, and Web of Science databases from inception to April 2025. …”
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353
Embedding and global stability in periodic 2-dimensional maps of mixed monotonicity
Published 2022“…In this paper, we consider nonautonomous second order difference equations of the form xn+1 = F(n, xn, xn−1), where F is p-periodic in its first component, non-decreasing in its second component and non-increasing in its third component. …”
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354
Carotid artery revascularization through a radiated field
Published 2003“…The safety and durability of carotid artery revascularization through a radiated field has been debated. We describe the immediate and long-term results in a series of 27 consecutive patients who received treatment over 12 years. …”
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355
Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019
Published 2023“…FindingsIn contrast with the decreasing trend of HF burden globally, EMR showed an increasing trend. …”
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356
Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal
Published 2019“…<p dir="ltr">Metabolic dysfunction of endothelial cells in hyperglycemia contributes to the development of vascular complications of diabetes where increased reactive glycating agent, methylglyoxal (MG), is involved. We assessed if increased MG glycation induced proteotoxic stress, identifying related metabolic drivers and protein targets. …”
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357
The Effect of High Dose Isoflavone Supplementation on Serum Reverse T3 in Euthyroid Men With Type 2 Diabetes and Post-menopausal Women
Published 2018“…</p><h3>Materials and Methods</h3><p dir="ltr"> We examined the effect of soy isoflavones on reverse tri-iodothyronine (or 3,3′,5′-tri-iodothyronine; rT<sub>3</sub>) in two studies comprising 400 patients: 200 men (study 1; 3 months) and 200 post-menopausal women (study 2; 6 months) who were randomized to consume 15 g soy protein with 66 mg of isoflavones (SPI) daily, or 15 g soy protein alone without isoflavones (SP) daily.…”
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358
Proteomics Analysis of Human Obesity Reveals the Epigenetic Factor HDAC4 as a Potential Target for Obesity
Published 2013“…Using this approach, a total of 47 proteins showed at least 1.5 fold change between lean and obese subjects. …”
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359
Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic anal...
Published 2020“…Under-5 deaths declined from 9·6 million (9·1–10·3) in 2000 to 5·0 million (4·3–6·0) in 2019. …”
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360
Hedonic valuation of land protection methods: implications for cluster development.
Published 2014“…The key findings of the study are: (i) proximity to national or state park land and to city or county open space has a significant positive impact on property values, while proximity to national forest land or to privately conserved land exhibits no significant effects; and, (ii) inclusion of a property within a cluster development decreases its value by 17 to 26 %. …”
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