يعرض 81 - 100 نتائج من 16,720 نتيجة بحث عن '(( 5 ppm decrease ) OR ((((( 5 nn decrease ) OR ( 5 n decrease ))) OR ( 5 nm decrease ))))', وقت الاستعلام: 1.11s تنقيح النتائج
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    Reactive oxygen species from mitochondria impacts trophoblast fusion and the production of endocrine hormones by syncytiotrophoblasts حسب O’Llenecia S. Walker (8486163)

    منشور في 2020
    "…Increased mitochondrial ROS resulted in a significant decrease in the transcripts which encode for proteins associated with fusion (<i>GCM1</i>, <i>ERVW-1</i>, and <i>ERVFRD-1</i>) resulting in a 5-fold decrease in the percentage of BeWo fusion. …"
  6. 86

    Discovery of Novel Pyrimidine-Based Capsid Assembly Modulators as Potent Anti-HBV Agents حسب WooChan Kim (10690503)

    منشور في 2021
    "…One of the synthesized derivatives, compound <b>23h</b> (R<sup>1</sup> = MeSO<sub>2</sub>, R<sup>2</sup> = 1-piperidin-4-amine, R<sup>3</sup> = 3-Cl-4-F-aniline) displayed potent inhibitory effects in the in vitro assays (52% inhibition in the protein-based assay at 100 nM and an IC<sub>50</sub> value of 181 nM in the serum HBV DNA quantification assay). …"
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    Characterization of a native ASIC1a-type current in deep projection neurons from laminae V. حسب Magda Chafaï (15307098)

    منشور في 2023
    "…Extracellular applications of the ASIC1a inhibitory peptides PcTx1 (30nM) or mambalgin-1 (1μM) both decrease the amplitude of native pH6.6-induced currents. …"
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    Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors حسب Mirko Scortichini (4007366)

    منشور في 2022
    "…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i><sub>i</sub> = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i><sub>i</sub> = 0.436 nM) substitution of the <i>N</i><sup>4</sup>-benzyloxy group decreased <i>K</i><sub>i</sub> by ∼20-fold. …"
  16. 96

    Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors حسب Mirko Scortichini (4007366)

    منشور في 2022
    "…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i><sub>i</sub> = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i><sub>i</sub> = 0.436 nM) substitution of the <i>N</i><sup>4</sup>-benzyloxy group decreased <i>K</i><sub>i</sub> by ∼20-fold. …"
  17. 97

    Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors حسب Mirko Scortichini (4007366)

    منشور في 2022
    "…We now expand the structure–activity relationship of pyrimidine nucleotides as human CD73 inhibitors. 4-Chloro (MRS4598 <b>16</b>; <i>K</i><sub>i</sub> = 0.673 nM) and 4-iodo (MRS4620 <b>18</b>; <i>K</i><sub>i</sub> = 0.436 nM) substitution of the <i>N</i><sup>4</sup>-benzyloxy group decreased <i>K</i><sub>i</sub> by ∼20-fold. …"
  18. 98

    Fig 5 - حسب Jiajia Li (184267)

    منشور في 2022
    الموضوعات:
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