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Combined Noncoding RNA-mRNA Regulomics Signature in Reprogramming and Pluripotency in iPSCs
منشور في 2022"…<div><p>Somatic cells are reprogrammed with reprogramming factors to generate induced pluripotent stem cells (iPSCs), offering a promising future for disease modeling and treatment by overcoming the limitations of embryonic stem cells. …"
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Klotho overexpression protects human cortical neurons from β-amyloid induced neuronal toxicity
منشور في 2025"…In this study, we utilised human induced pluripotent stem cells (iPSCs) engineered with a doxycycline-inducible system to overexpress <i>KLOTHO</i> and generated 2D cortical neuron cultures from these cells. …"
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Aortic valve function post-replacement of severe aortic stenosis by transcatheter procedure versus surgery: a systematic review and metanalysis
منشور في 2021"…TAVR was associated with 37% (95% CI [0.51–0.78) mean RR reduction of post-procedural PPM, a decrease that was not affected by the surgical risk at inclusion, neither by the transcatheter heart valve system. …"
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High-Performance Acetic Acid Sensing Using Cerium-MoS₂ Composite for Beverages and Food Processing Industry
منشور في 2025"…Furthermore, the repeatability of the Ce<sub>0.6</sub> -MoS<sub>2</sub> sensor was assessed over 30 days, and a marginal decrease of 5% in response was observed from day 1 to day 30.…"
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Low-Dose Eltrombopag in a Patient with Chronic Idiopathic Thrombocytopenic Purpura Post Sleeve Gastrectomy
منشور في 2020"…Here we are reporting a 46-year-old female with ITP and sleeve gastrectomy who responded to low-dose eltrombopag 25 mg every other day, which is equivalent to 12.5 mg daily, and maintained adequate platelet counts on this dose.…"
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Impact of Life-coaching on Students' Wellbeing and Engagement Levels in a Preparatory School in Qatar
منشور في 2019"…However, the decrease was overall slighter with coaching group students. …"
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Investigating the Role of FOXA2 Transcription Factor in Adipogenesis Using Human-Induced Pluripotent Stem Cells
منشور في 2025"…Therefore, in this study, we aimed to investigate the role of <i>FOXA2</i> in adipogenesis using previously established wild-type induced pluripotent stem cells (WT-iPSCs) and <i>FOXA2</i> knockout iPSCs (FOXA2 KO iPSCs). …"
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Simultaneous Bilateral Neck of Femur Fracture in a Young Adult with Underlying Metabolic Disturbances
منشور في 2020"…We report a case of a 31-year-old male patient who presented to the emergency department with bilateral hip pain and inability to bear weight after a sudden loss of consciousness and fall while running on a treadmill. …"
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Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1<sup>+</sup>/NKX6.1<sup>+</sup> progenitors
منشور في 2024"…Upon differentiating iPSCs lacking RFX6 into pancreatic islets, a significant decrease in PDX1 expression at the PF stage was observed, although this did not affect PPs co-expressing PDX1 and NKX6.1. …"
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Does Ultrasound Really Good Enough to Evaluate the Pneumothorax in the Emergency Department
منشور في 2023"…The average age of the patients was 76.5%, with the youngest patient being 18 years old and the oldest one being 90 years old. …"
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Anabolic steroids-induced delirium
منشور في 2020"…</p><h3>Patient concern</h3><p dir="ltr">A 33-year-old gentleman presented with increased aggression, hostility, and destructive impulses. …"
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Aorta deformation linked to heart disease
منشور في 2015"…Hala Mahfouz Badran of Menoufiya University, Egypt, and her colleagues recruited 141 HCM patients, aged 5–62 years old and without other cardiovascular risk factors, and 66 age- and sex-matched healthy controls. …"
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Chiropractic manipulations gone wrong
منشور في 2016"…<p dir="ltr">Neurologists in Qatar report in the Qatar Medical Journal that a 55-year-old man was admitted to their hospital with a stroke that occurred one week after undergoing chiropractic neck manipulation to resolve chronic neck pain . …"
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Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019
منشور في 2023"…Age-standardised prevalence, YLDs, and underlying causes of HF were compared by 5-year age groups (considering 15 years old and more), sex (male and female), and countries. …"
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Double versus triple arthrodesis for adult-acquired flatfoot deformity due to stage III posterior tibial tendon insufficiency: a prospective comparative study of two cohorts
منشور في 2022"…Patients with AAFD stage III aged between 15 and 40 years old were assigned to double arthrodesis or triple arthrodesis. …"
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