Evaluating the Potential of Ozone Microbubbles for Inactivation of Tulane Virus, a Human Norovirus Surrogate حسب Bozhong Guan (18598178)

"…After 2, 10, and 20 min postgeneration, the ozone concentration of microbubbles naturally decreased from 4 ppm to 3.2 ± 0.2, 2.26 ± 0.19, and 1.49 ± 0.23 ppm and resulted in 1.43 ± 0.44, 0.88 ± 0.5, and 0.68 ± 0.53 log₁₀ viral reductions, respectively, while the ozone concentration of aqueous ozone decreased from 4 ppm to 2.52 ± 0.07, 0.43 ± 0.05, and 0.09 ± 0.01 ppm and produced 0.8 ± 0.28, 0.29 ± 0.41, and 0.16 ± 0.21 log₁₀ reductions against Tulane virus, respectively (<i>p</i> = 0.0526), suggesting that structuring of ozone in the bubbles over the applied treatment conditions did not have a significant effect, though future study with continuous generation of ozone microbubbles is needed.…"

Identification of druggable small molecule antagonists of the <i>Plasmodium falciparum</i> hexose transporter PfHT and assessment of ligand access to the glucose permeation pathway... حسب Monique R. Heitmeier (6686069)

"…WU-1 showed comparable potency in blocking 2-DG uptake in freed parasites and inhibiting parasite growth, with an IC₅₀ of 6.1 ± 0.8 μM and EC₅₀ of 5.5 ± 0.6 μM, respectively. …"

Cell invasiveness in metastatic cancer cells exposed to their IC₅₀ Aur for 24 h. حسب Sara Rodríguez-Enríquez (4373332)

Migratory capacity in metastatic cancer cells exposed to IC₅₀ Aur for 24 h. حسب Sara Rodríguez-Enríquez (4373332)

Proportional symbol map of arsenic (As) in micrograms per liter (μg/L) in Bangladesh’s drinking well water. حسب Seth H. Frisbie (7821866)

The first regression of log of confirmed cases vs consecutive days for 4 of the total of 50 countries is shown. حسب Adam Kaplin (10156481)

The aging-induced decrease in the number of dendritic branches in neurons of the hippocampus and cerebral cortex was attenuated by the administration of GTDE. حسب Hui-Chuan Kuo (12368492)

TTLL12 knockdown in HEp-2 and DU145 cells decreases cell survival in the presence of nitrotyrosine. حسب Amit Deshpande (255211)

Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPA₂), UCM-14216, Ameliorates Spinal Cord Injury in Mice حسب Nora Khiar-Fernández (8130210)

"…Inhibition of the type 2 lysophosphatidic acid receptor (LPA₂) has recently emerged as a new potential pharmacological approach to decrease SCI-associated damage. Toward validating this receptor as a target in SCI, we have developed a new series of LPA₂ antagonists, among which compound <b>54</b> (UCM-14216) stands out as a potent and selective LPA₂ receptor antagonist (<i>E</i>_max = 90%, IC₅₀ = 1.9 μM, <i>K</i>_D = 1.3 nM; inactive at LPA_1,3–6 receptors). …"

Novel Antagonist of the Type 2 Lysophosphatidic Acid Receptor (LPA₂), UCM-14216, Ameliorates Spinal Cord Injury in Mice حسب Nora Khiar-Fernández (8130210)

"…Inhibition of the type 2 lysophosphatidic acid receptor (LPA₂) has recently emerged as a new potential pharmacological approach to decrease SCI-associated damage. Toward validating this receptor as a target in SCI, we have developed a new series of LPA₂ antagonists, among which compound <b>54</b> (UCM-14216) stands out as a potent and selective LPA₂ receptor antagonist (<i>E</i>_max = 90%, IC₅₀ = 1.9 μM, <i>K</i>_D = 1.3 nM; inactive at LPA_1,3–6 receptors). …"

Example of the process used to determine time dependence of <i>ε</i>_max and IC₅₀. حسب Hope Murphy (8843516)

Partial correlation of <i>ε</i>_max (left column) and IC₅₀ (right column) estimates at 10 days and 20 days (first and second bar of each color, respectively) o... حسب Hope Murphy (8843516)

Representative μCT image slice of the femoral cortical mid-diaphysis (thresholded). حسب Daksh Arora (16510065)

Jag2 knockdown ameliorates mitochondrial dysfunction induced by hypoxia. حسب Hanhan Liu (568151)

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Immunoblot images of α-SMA, PCNA and Sirt1. حسب Hanhan Liu (568151)

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Identification of Potent DNA Gyrase Inhibitors Active against Mycobacterium tuberculosis حسب Bongkochawan Pakamwong (12315428)

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Jag2 expression is upregulated in hypoxia-treated rats and PASMCs. حسب Hanhan Liu (568151)

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Primers for real-time PCR (rat). حسب Hanhan Liu (568151)

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Raw image of western blots. حسب Hanhan Liu (568151)

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Inhibition of Jag2 effectively ameliorates hypoxia-induced PH in rats. حسب Hanhan Liu (568151)

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