AMPK Activation Attenuates Albumin-induced Alterations in Renal Tubular Cells In Vitro حسب Allouch, Soumaya

"…Similarly, the phosphorylation of AKT and P70S6K (a downstream target of mTOR) was increased by more than 1.5-fold in cells subjected to albumin treatment. In addition, albumin treatment caused a dose-dependent reduction in AMPK phosphorylation and about 66% decrease in the expression of autophagy marker LC3-II. …"
احصل على النص الكامل
احصل على النص الكامل

Opportunities, challenges and trade-offs with decreasing avoidable food waste in the UK حسب Patel, Shivalee

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit, Masania

"…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit, Masania

"…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Chronic melatonin treatment improves obesity by inducing uncoupling of skeletal muscle SERCA-SLN mediated by CaMKII/AMPK/PGC1α pathway and mitochondrial biogenesis in female and ma... حسب Salagre, D.

"…Furthermore, melatonin treatment enhanced the expression ratio of P-CaMKII/CaMKII and P-AMPK/AMPK. In addition, it rose mitochondrial biogenesis. …"
احصل على النص الكامل
احصل على النص الكامل

Turning point in COVID-19 severity and fatality during the pandemic: a national cohort study in Qatar حسب Chemaitelly, Hiam

احصل على النص الكامل
احصل على النص الكامل

A robust experimental-based artificial neural network approach for photovoltaic maximum power point identification considering electrical, thermal and meteorological impact حسب Gowid, Samer

"…The results showed a decrease in the MSE of Vmp by 74.3% (from 1.6 V to 0.411 V), and in the MSE of Imp by 95% (from 4.4e−6 A to 2.16e−7 A), respectively. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Effects of superelastic nano-NiTi additions on electroless Ni –P coating properties under bending حسب MacLean M.

احصل على النص الكامل
احصل على النص الكامل

Blue photobiomodulation LED therapy impacts SARS-CoV-2 by limiting its replication in Vero cells حسب Zupin, L.

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Comprehensive thermoeconomic, exergoeconomic, and optimization analyses of direct oxy-combustion supercritical CO2 intercooled and reheated cycles under design and off-design condi... حسب Al-Ammari, Wahib A.

"…This study presents comprehensive energetic, exergetic, exergoeconomic, and economic (4E) performance analyses for four direct oxy-combustion (DOC) supercritical carbon dioxide (sCO2) power cycles at design, off-design, and part-load conditions. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Thermal and mechanical characterization of injection moulded high density polyethylene/paraffin wax blends as phase change materials حسب Sotomayor, M.E.

احصل على النص الكامل
احصل على النص الكامل

Driver Drowsiness Detection Study using Heart Rate Variability analysis in Virtual Reality Environment حسب Chowdhury, Muhammad E.H.

احصل على النص الكامل
احصل على النص الكامل

Anti-Neoplastic Effects of Annonacin against Renal Cell Carcinoma حسب Munusamy, Shankar

"…Results: hour annonacin treatment caused a significant and dose-dependent decrease in the viability of CaKi-2 cells, i.e., 42% in 0.5 ?…"
احصل على النص الكامل
احصل على النص الكامل

Sestrin2 suppression aggravates oxidative stress and apoptosis in endothelial cells subjected to pharmacologically induced endoplasmic reticulum stress حسب Fatima, Munazza T

"…Importantly, SESN2 silencing, unlike thapsigargin, caused a dramatic decrease in protein expression and phosphorylation of Akt, a critical pro-survival hub and component of the AMPK/Akt/mTORC1 axis. …"
احصل على النص الكامل
احصل على النص الكامل

Optimization of performance and emission characteristics of CI engine fueled with Jatropha biodiesel produced using a heterogeneous catalyst (CaO) حسب Singh, A.

"…The optimum performance and emission characteristics (BP, BTHE, HC and NOx) are found to be 2.258 KW, 29.05%, 6.31 ppm, and 159.5 ppm respectively. The performance of B20 fueled engine was almost comparable to that of diesel fuel. …"
احصل على النص الكامل
احصل على النص الكامل

USING EMBEDDED MACHINE LEARNING IN THE PHYSICAL WORLD TO DETECT TOXICITY IN SPOKEN LANGUAGE حسب ABU NADA, AHLAM HUSNI

"…In our study, quantization demonstrated a significant reduction in model size by almost fourfold and a 3.3-fold decrease in RAM usage. The marginal average F1 score decrease was limited to only 1%. …"
احصل على النص الكامل

Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... حسب Salma, Younes

"…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). Among VN individuals, anti-S1 IgA levels began to decrease significantly (1.4-fold; p = 0.007) after two months, and both NtAb and S-RBD IgG levels began to decline significantly (NtAb: 2.0-fold; p = 0.042, S-RBD IgG: 2.4-fold; p = 0.035) after three months. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... حسب Salma, Younes

"…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). Among VN individuals, anti-S1 IgA levels began to decrease significantly (1.4-fold; p = 0.007) after two months, and both NtAb and S-RBD IgG levels began to decline significantly (NtAb: 2.0-fold; p = 0.042, S-RBD IgG: 2.4-fold; p = 0.035) after three months. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The Separation of Emulsified Water/Oil Mixtures through Adsorption on Plasma-Treated Polyethylene Powder حسب Abdulkareem, Asma

"…The efficiency of the plasma-treated LDPE powder in oil removal was found to be dependent on the initial oil concentration. It decreased from 96.7% to 79.5% as the initial oil concentration increased from 75 ppm to 200 ppm. …"
احصل على النص الكامل
احصل على النص الكامل

The mitochondria: A target of polyphenols in the treatment of diabetic cardiomyopathy حسب Bhagani, Humna

"…The most important intermediates by which polyphenols exert their protective effect include Bcl-2, UCP2, SIRT-1, AMPK and JNK1. Bcl-2 acts to attenuate apoptosis, UCP2 decreases oxidative stress, SIRT-1 increases mitochondrial biogenesis and decreases oxidative stress, AMPK increases autophagy, and JNK1 decreases apoptosis and increases autophagy. …"
احصل على النص الكامل
احصل على النص الكامل