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1
Combined Noncoding RNA-mRNA Regulomics Signature in Reprogramming and Pluripotency in iPSCs
منشور في 2022"…<div><p>Somatic cells are reprogrammed with reprogramming factors to generate induced pluripotent stem cells (iPSCs), offering a promising future for disease modeling and treatment by overcoming the limitations of embryonic stem cells. …"
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2
Klotho overexpression protects human cortical neurons from β-amyloid induced neuronal toxicity
منشور في 2025"…In this study, we utilised human induced pluripotent stem cells (iPSCs) engineered with a doxycycline-inducible system to overexpress <i>KLOTHO</i> and generated 2D cortical neuron cultures from these cells. …"
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3
A robust experimental-based artificial neural network approach for photovoltaic maximum power point identification considering electrical, thermal and meteorological impact
منشور في 2020"…The results showed a decrease in the MSE of V<sub>mp</sub> by 74.3% (from 1.6 V to 0.411 V), and in the MSE of I<sub>mp</sub> by 95% (from 4.4e−6 A to 2.16e−7 A), respectively. …"
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4
Effect of Hypoxia on Maximal Fat Oxidation Rate During Incremental Cycling : Relationship to the Gas Exchange Threshold
منشور في 2024"…Pearson correlation was used to assess the relationship between MFO and GET.</p><h3>Results</h3><p dir="ltr">Fat oxidation rate was decreased in HYPO across all stages (main effect of condition: <i>P</i> < 0.001; η<sub>p</sub><sup>2</sup> = 0.64). …"
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5
Nonlinear Control of Brushless Dual-Fed Induction Generator With a Flywheel Energy Storage System for Improved System Performance
منشور في 2025"…The system is further enhanced with Optimal Torque Control (OTC) and Maximum Power Point Tracking (MPPT) to maximize wind energy extraction. …"
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Sleeve Gastrectomy in Patients with Type 2 Diabetes: Anthropometric and Cardiometabolic Improvements at 1, 3, 5, 7, and 9 years—Are the Initial Benefits Sustained?
منشور في 2025"…Fasting blood glucose decreased significantly across the five time points, from 9.27 ± 4.11preop to 7.06 ± 2.70 <sub>year9 </sub>mmol/L. …"
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7
Generalized and pregnancy-related anxiety prevalence and predictors among pregnant women attending primary health care in Qatar, 2018–2019
منشور في 2020"…However, we revealed that different determinants influence the two types of anxiety.</p><h3>Limitations</h3><p dir="ltr">There is no recognized optimal cut-off point to distinguish ‘high risk’ in pregnancy-related anxiety scales.…"
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8
Aortic valve function post-replacement of severe aortic stenosis by transcatheter procedure versus surgery: a systematic review and metanalysis
منشور في 2021"…TAVR was associated with 37% (95% CI [0.51–0.78) mean RR reduction of post-procedural PPM, a decrease that was not affected by the surgical risk at inclusion, neither by the transcatheter heart valve system. …"
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9
High-Performance Acetic Acid Sensing Using Cerium-MoS₂ Composite for Beverages and Food Processing Industry
منشور في 2025"…Furthermore, the repeatability of the Ce<sub>0.6</sub> -MoS<sub>2</sub> sensor was assessed over 30 days, and a marginal decrease of 5% in response was observed from day 1 to day 30.…"
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10
Optimization of design and operation of solar assisted district cooling systems
منشور في 2020"…Moreover, the existence of the cold-water TES in the system depends on the chosen chiller capacity and the cooling demand of the case study. …"
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11
Phosphate removal from synthetic and treated sewage effluent by carbide derive carbon
منشور في 2020"…The determined thermodynamic parameters point out that PO<sub>4</sub><sup>3-</sup> adsorption through CDC is endothermic, feasible and spontaneous. …"
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12
Investigating the Role of FOXA2 Transcription Factor in Adipogenesis Using Human-Induced Pluripotent Stem Cells
منشور في 2025"…Therefore, in this study, we aimed to investigate the role of <i>FOXA2</i> in adipogenesis using previously established wild-type induced pluripotent stem cells (WT-iPSCs) and <i>FOXA2</i> knockout iPSCs (FOXA2 KO iPSCs). …"
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13
STEM: spatial speech separation using twin-delayed DDPG reinforcement learning and expectation maximization
منشور في 2025"…Additionally, it reduces the required training data by 39 times, training time by 36 times, model size by 6 times, real time factor (RTF) by 1 point, and multiply-accumulate operations (MACs) by 9 times compared to a recently proposed lightweight transformer-based encoder-decoder framework, while offering a slight decrease in PESQ score (by 0.45 points).…"
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14
Hydrothermal and irreversibility numerical analysis of helical coil energy storage tank with nano-encapsulated PCMs: A comprehensive study with magnetic filled, Soret/Dufour, and m...
منشور في 2025"…On the other hand, average values of Nusselt and Sherwood are decreased with the rise of the Hartmann number. Furthermore, Nusselt average and Sherwood’s average decrease by 21.4 % and 24.9 % respectively when Darcy’s number increases from 0.1 to 10<sup>-4</sup>.…"
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Effect of Hypoxia on Muscle Activation During Incremental Exercise at Equivalent Relative Intensity
منشور في 2024"…<h3>Introduction</h3><p dir="ltr">The objective of this study was to investigate the impact of hypoxia on the connection between metabolic stress, adjusted for relative intensity, absolute power production, and muscle activation as indicated by EMG activity in the context of step and ramp incremental exercise.…"
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16
Trends of the Dementia Burden in South Asia: An Analysis of 2021 Global Burden of Disease Study
منشور في 2025"…The objective is to identify key risk factors, such as metabolic and behavioral health risks, and assess regional variations in the burden of ADoD across five South Asian countries India, Pakistan, Bangladesh, Nepal, and Bhutan.</p><h3>Methods</h3><p dir="ltr">Data from the Global Burden of Disease (GBD) 2021 report were analyzed using descriptive statistics and join point regression analysis. …"
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Predictors of mortality and morbidity in critically ill COVID‐19 patients: An experience from a low mortality country
منشور في 2022"…Factors independently associated with mortality included older age ([OR]; 2.3 [95% CI; 1.92–2.75] for each 10-year increase in age, <i>p</i> < 0.001), chronic kidney disease (OR; 1.9 [95% CI; 1.02–3.54], <i>p</i> = 0.04), active malignancy (OR; 6.15 [95% CI; 1.79–21.12], <i>p</i> = 0.004), lower platelet count at ICU admission (OR; 1.41 [95% CI; 1.13–1.75] for each 100 × 103/µl decrease, <i>p</i> = 0.002), higher neutrophil-to-lymphocyte ratio at admission (OR; 1.01 [95% CI; 1–1.02] for each 1- point increase, <i>p</i> = 0.016), higher serum ferritin level at admission (OR; 1.05 [(95% CI; 1.02–1.08] for each 500 µg/L increase, <i>p</i> = 0.002), and higher serum bilirubin level at admission (OR; 1.19 [95% CI; 1.04–1.36] for each 10 μmol/L increase, <i>p</i> = 0.01). …"
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18
Assessment of resin systems as solution for well integrity challenge in carbonate reservoirs
منشور في 2023"…</p><p> </p></div><h2>Other Information</h2> <p> Published in: Journal of Petroleum Exploration and Production Technology<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s13202-023-01608-3" target="_blank">https://dx.doi.org/10.1007/s13202-023-01608-3</a></p>…"
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Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1<sup>+</sup>/NKX6.1<sup>+</sup> progenitors
منشور في 2024"…Upon differentiating iPSCs lacking RFX6 into pancreatic islets, a significant decrease in PDX1 expression at the PF stage was observed, although this did not affect PPs co-expressing PDX1 and NKX6.1. …"
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20
Flavonoids Alleviate Peripheral Neuropathy Induced by Anticancer Drugs
منشور في 2021"…Results: Flavonoids inhibit several essential mechanisms of CIPN, such as proinflammatory cytokine release, astrocyte and microglial activation, oxidative stress, neuronal damage and apoptosis, mitochondrial damage, ectopic discharge, and ion channel activation. They decreased the severity of certain CIPN symptoms, such as thermal hyperalgesia and mechanical, tactile, and cold allodynia. …"