Modulation of SLFN11 induces changes in DNA Damage response in breast cancer حسب Christophe Michel Raynaud (17449906)

"…We then used the modified cell lines to quantify the alteration in chemo sensitivity of those cells to treatment with DNA Damaging Agents (DDAs) such as Cisplatin and Epirubicin or DNA Damage Response (DDRs) drugs like Olaparib. …"

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity حسب Wesam S. Ahmed (10170053)

"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"

Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex حسب Wesam S. Ahmed (10170053)

"…<p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences <a href="https://dx.doi.org/10.3389/fmolb.2022.846996" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.846996</a>, published online 22 July 2022.…"

The ortholog of human ssDNA-binding protein SSBP3 influences neurodevelopment and autism-like behaviors in <i>Drosophila melanogaster</i> حسب Safa Salim (9186786)

"…One such gene is the single-stranded DNA-binding protein 3 (<i>SSBP3</i>) and its Drosophila melanogaster ortholog is called sequence-specific single-stranded DNA-binding protein (<i>Ssdp</i>). …"

Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas حسب Abu Saleh Md Moin (6189512)

A CFD- RSM study of cuttings transport in non-Newtonian drilling fluids: Impact of operational parameters حسب Abdelrahman M. Awad (16932519)

"…Less effective cuttings transportation (i.e lower CTR) was observed when the hole angle deviated from the vertical. …"

Proteomics Analysis of Human Obesity Reveals the Epigenetic Factor HDAC4 as a Potential Target for Obesity حسب Mohamed Abu-Farha (18535590)

Aortic valve function post-replacement of severe aortic stenosis by transcatheter procedure versus surgery: a systematic review and metanalysis حسب Charbel Abi Khalil (14150028)

"…TAVR was associated with 37% (95% CI [0.51–0.78) mean RR reduction of post-procedural PPM, a decrease that was not affected by the surgical risk at inclusion, neither by the transcatheter heart valve system. …"

High-Performance Acetic Acid Sensing Using Cerium-MoS₂ Composite for Beverages and Food Processing Industry حسب E. Safamariyam (22330186)

"…Furthermore, the repeatability of the Ce_0.6 -MoS₂ sensor was assessed over 30 days, and a marginal decrease of 5% in response was observed from day 1 to day 30.…"

BRET-Based Biosensors for Nucleic Acid Detection and Impact of Molecular Crowding Monitoring حسب Asfia Sultana (19170880)

"…Our work extended to designing BioNADs targeting SARS-CoV-2 variants by conjugating specific, fluorescently modified molecular beacons to NLuc-functionalized DNA for viral nucleic acid detection. Moreover, our study revealed that the decrease in BRET efficiency of BioNADs upon viral oligo binding could be visualized as a color change using a cell phone camera. …"

Visitors off the trail: Impacts on the dominant plant, bryophyte and lichen species in alpine heath vegetation in sub-arctic Sweden حسب Monika, Rawat

"…The results showed that proximity to the trail did not cause a decrease in the majority of dominant species, with none of the eight most dominant vascular plants showing any significant effects of proximity to the trail. …"
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BRET-based biosensors for SARS-CoV-2 oligonucleotide detection حسب Asfia Sultana (19170880)

"…Specifically, we designed BioODs against the SARS-CoV-2 parental (Wuhan strain) and B.1.617.2 Delta variant through the conjugation of specific, fluorescently modified molecular beacons (sensor module) through a complementary oligonucleotide handle DNA functionalized with the NanoLuc (NLuc) luciferase protein such that the dissolution of the molecular beacon loop upon the binding of the viral oligonucleotide will result in a decrease in BRET efficiency and, thus, a change in the bioluminescence spectra. …"

Automated detection of posterior urethral valves in voiding cystourethrography images: A novel AI-Based pipeline for enhanced diagnosis and classification حسب Saidul Kabir (15302407)

Salicylic acid restricts mercury translocation by activating strong antioxidant defense mechanisms in sweet pepper (Capsicum annum L.) حسب Muhammad Fasih Khalid (10652246)

"…Spraying of 100 μ M SA at three different Hg levels, i.e., 0 μ M, 50 μ M, 100 μ M, and 150 μ M. The maximum decrease in photosynthetic machinery, plant growth attributes (shoot length, root length, no. of leaves, fresh and dry biomass (shoot and root)), and more accumulation of Hg in leaves, roots, and fruits of sweet pepper. …"

Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-... حسب Mohamed Yassin (4166515)

"…While some real-world studies have reported a decrease in VOCs and hospitalizations, the results are inconsistent and not conclusive. …"

A combined experimental and computational study of the effect of electron irradiation on the transport properties of aromatic and aliphatic molecular self-assemblies حسب Y. Tong (18394389)

"…This structural modification also results in a significant decrease of the current. These findings can be useful in understanding the processes during the electron irradiation of molecular SAMs.…"

3D Concrete Printing Sustainability: A Comparative Life Cycle Assessment of Four Construction Method Scenarios حسب Malek Mohammad (17150977)

"…This paper investigates the environmental tradeoff of utilizing 3DCP over conventional construction by conducting a detailed cradle-to-gate life cycle assessment (LCA) study of four case-scenarios (conventional concrete construction, 3DCP with reinforcement elements, 3DCP without any reinforcement, and 3DCP without any reinforcement and utilizing a lightweight printable concrete material.) …"

Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar حسب Doua Abdelrahman (17280667)

"…Results: Only 1.4% (70/5026) of the samples had detectible B19V DNA in their blood. B19V DNA prevalence statistically decreased with age (p = 0.03). …"

Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling حسب Sabah Akhtar (5809925)

"…SNG treatment of MM cells resulted in a dose-dependent decrease in cell viability through mitochondrial membrane potential loss and activation of caspase 3, 9, and cleavage of PARP. …"

Mechanisms behind the immediate effects of Roux-en-Y gastric bypass surgery on type 2 diabetes حسب Roland E Allen (19187023)

"…I.e., the largest possible decrease in glucose predicted by the model is smaller than reported decreases, and the model predicts no decrease whatsoever in glucose ×insulin, in contrast to large observed decreases in homeostatic model assessment insulin resistance (HOMA-IR). …"