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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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apoA2 correlates to gestational age with decreased apolipoproteins A2, C1, C3 and E in gestational diabetes
منشور في 2021"…</p><h3>Conclusions</h3><p dir="ltr">Apoproteins apoA2, apoC1, apoC3 and apoE are decreased in women with GDM and may have a role in inflammation, as apoA2 and C3 correlated with CRP. …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…This may be achieved by decreasing protein glycation by the reactive metabolite, methylglyoxal (MG). …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…This may be achieved by decreasing protein glycation by the reactive metabolite, methylglyoxal (MG). …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…Specifically, the N501Y mutation in the S1 spike receptor binding domain (S1-RBD) of these variants have been reported to increase its affinity for ACE2, although the basis for this is not entirely clear yet. …"
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eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways
منشور في 2018"…These effects are likely dependent on the inhibition of eIF4A activity since we observed similar results using PatA. …"
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Physical Exercise Reduces the Expression of RANTES and Its CCR5 Receptor in the Adipose Tissue of Obese Humans
منشور في 2014"…<p dir="ltr">RANTES and its CCR5 receptor trigger inflammation and its progression to insulin resistance in obese. …"
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A Scoping Review to Find Out Worldwide COVID-19 Vaccine Hesitancy and Its Underlying Determinants
منشور في 2021"…Intervention- (i.e., COVID-19 vaccine) and outcome- (i.e., hesitancy) related terms were used to search in these databases. …"
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Genome-Wide Association Study of Vitamin D Deficiency in the Middle East With a Relevant Characterization of the Novel <i>SDR42E1 </i>Gene
منشور في 2023"…Cellular viability also decreased significantly after the knockout of SDR42E1 in the HCT116 cells.…"
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Assessment of treatment burden and its impact on quality of life in dialysis-dependent and pre-dialysis chronic kidney disease patients
منشور في 2021"…<h3>Background</h3><p dir="ltr">The management of chronic kidney disease (CKD) and its complications places a significant burden on patients, resulting in impairment of their health-related quality of life (HR-QOL). …"
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Visible Light Photocatalytic Activity of Ag/WO<sub>3</sub> Nanoparticles and its Antibacterial Activity Under Ambient Light and in The Dark
منشور في 2022"…Ultraviolet–visible spectra analysis observed a large redshift in the absorbing band edge and decreased bandgap energy from 2.6 to 2.1 eV. Photocatalytic analysis at different concentrations of 1% Ag/WO<sub>3</sub> under visible light indicated a high degradation efficiency. …"
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Effects of the addition of a high energy density fuel, adamantane to diesel on its cetane number, sooting propensity, and soot nanostructural properties
منشور في 2022"…Another method to reduce soot could be to increase its reactivity by altering its physicochemical properties (e.g., introducing curvatures in its nanostructures) so that it oxidizes inside the engine or flame. …"
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The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties
منشور في 2025"…Hardness analysis revealed significant decreases in microhardness in the bleached group compared to the control group (p < 0.05). …"
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The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties
منشور في 2025"…Hardness analysis revealed significant decreases in microhardness in the bleached group compared to the control group (<i>p </i> < 0.05). …"