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81
Application of Fe<sub>3</sub>O<sub>4</sub> magnetite nanoparticles grafted in silica (SiO<sub>2</sub>) for oil recovery from oil in water emulsions
منشور في 2021"…Using an MD<sub>dose</sub> as low as 10 mg/L attained a %<sub>hdem</sub> in the range of 93% - 4.3% for O/W mixtures with C<sub>oil</sub> < 2000 mg/L, which slightly decreased to ~90% for higher concentrations. …"
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82
Exploring Sustainable Strategies for Shelter Design at Refugee Camps: The Case of Domiz 1 Refugee Camp in Iraq
منشور في 2017"…Furthermore, a 42% decrease in cooling loads, and 31% decrease in heating loads was achieved by using the proposed wall panel, the sunspace during winter, and the roof canopy during winter, in comparison to the baseline case, the UNHCR tent.…"
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83
Methylation at global LINE-1 repeats in human blood are affected by gender but not by age or natural hormone cycles
منشور في 2011"…In contrast, a decrease in methylation was observed in estrogen-treated T47-Kbluc cell lines strongly expressing estrogen receptor. …"
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article -
84
Unraveling the impaired incretin effect in obesity and type 2 diabetes: Key role of hyperglycemia-induced unscheduled glycolysis and glycolytic overload
منشور في 2024"…<p>Glucagon-like peptide-1 (GLP-1) agonists and GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) co-agonists are major treatment options for subjects with obesity and patients with type 2 diabetes mellitus (T2DM). …"
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85
mTORC1 loss impairs epidermal adhesion via TGF-b/Rho kinase activation
منشور في 2017"…In mice with conditional epidermal loss of the mTORC1 components Rheb or Rptor, mTORC1 loss of function unexpectedly resulted in a profound skin barrier defect with epidermal abrasions, blistering, and early postnatal lethality, due to a thinned epidermis with decreased desmosomal protein expression and incomplete biochemical differentiation. …"
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article -
86
Trends in criminal convictions in Japan for vehicle collisions where one driver suffers from an epileptic seizure
منشور في 2015"…We used LEX/DB that is a database of the precedent after 1875 in Japan, too. …"
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87
RHOG activates RAC1 through CDC42 leading to tube formation in vascular endothelial cells
منشور في 2019"…While knocking down either RHO, GTPase did not affect p-AKT levels, and p-ERK decreased in response to the knocking down of RHOG, CDC42 or RAC1. …"
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article -
88
1,2,4-Trimethylbenzene Transformation Reaction Compared With Its Transalkylation Reaction With Toluene Over USY Zeolite
منشور في 2020"…1,2,4-Trimethylbenzene (TMB) transalkylation with toluene has been studied over USY zeolite type catalyst using a riser simulator that mimics the operation of a fluidized-bed reactor. …"
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article -
89
A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
منشور في 2025"…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…"
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article -
90
Cytotoxicity of [HuArgI (co)-PEG5000]-induced arginine deprivation to ovarian Cancer cells is autophagy dependent
منشور في 2019"…Ovarian cancer cell lines were negative for annexinV staining while showing loss of membrane integrity and absence of caspase activation, indicating caspase-independent, non-apoptotic cell death. [HuArgI (Co)-PEG5000]-induced arginine deprivation led to extensive and prolonged activation of autophagy, which proved to be deleterious to cell survival since its inhibition led to a significant decrease in cytotoxicity. …"
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article -
91
In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation
منشور في 2013"…We observed ATP depletion under OGD vs. hypoxia and propose that ATP depletion enhances translational suppression, overcoming the selective synthesis of HIF concurrent with global decreases in protein synthesis in hypoxia. Taken together, these findings biochemically characterize a practical reporter for monitoring HIF-1α levels and support a novel model for HIF regulation in an in vitro model of human ischemia.…"
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article -
92
Epstein–Barr Virus Epidemiology, Serology, and Genetic Variability of LMP-1 Oncogene Among Healthy Population: An Update
منشور في 2018"…Here, we provide a review of the EBV epidemiology and the genetic variability of the oncogene LMP-1. …"
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93
Positive regulation of oxidative phosphorylation by nuclear myosin 1 protects cells from metabolic reprogramming and tumorigenesis in mice
منشور في 2023"…<p dir="ltr">Metabolic reprogramming is one of the hallmarks of tumorigenesis. Here, we show that nuclear myosin 1 (NM1) serves as a key regulator of cellular metabolism. …"
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94
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
منشور في 2019"…<p>Tumor progression through immune evasion is a major challenge in cancer therapy. Recent studies revealed that enhanced PD-L1 expression in cancer stem cells is linked to immune evasion. …"
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95
The contribution of autophagy in glioblastoma multiforme cells treated with human recombinant arginase I-induced arginine deprivation. (c2018)
منشور في 2018"…Moreover, it is resistant to traditional chemotherapies and radiotherapies. All this results in a poor survival rate in GBM patients, which doesn’t exceed 1 year. …"
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masterThesis -
96
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97
SARS‐CoV‐2 infection triggers more potent antibody‐dependent cellular cytotoxicity (ADCC) responses than mRNA‐, vector‐, and inactivated virus‐based COVID‐19 vaccines
منشور في 2024"…We analyzed ADCC activity targeting SARS‐CoV‐2 spike (S) and nucleocapsid (N) proteins in convalescent sera following WT SARS‐CoV‐2‐infection (<i>n</i> = 91), including symptomatic and asymptomatic infections, omicron‐infection (<i>n</i> = 8), COVID‐19 vaccination with messenger RNA‐ (mRNA)‐ (BNT162b2 or mRNA‐1273, <i>n</i> = 77), adenovirus vector‐ (<i>n</i> = 41), and inactivated virus‐ (<i>n</i> = 46) based vaccines, as well as post‐mRNA vaccination BTI caused by omicron (<i>n</i> = 28). …"
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98
Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017)
منشور في 2017"…This absence of caspase activation was confirmed by a 72 hours cytotoxicity assay on Panc-1 cells, which revealed the failure of the pan-caspase inhibitor, Z-VAD, to reverse or decrease arginine depletion-triggered cell death. …"
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masterThesis -
99
Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells
منشور في 2025"…Similarly, genetic knockdown of HSP90 in RKO cells produced comparable effects, including reduced cell survival and a decreased PINK1/BNIP3 ratio.</p><h3>Conclusion</h3><p dir="ltr">Targeting HSP90 in colon cancer cells disrupts their survival by decreasing PINK1 and increasing BNIP3, which activates oxidative and endoplasmic reticulum stress, ultimately triggering apoptosis.…"
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100
Soluble Neuropilin-1 Response to Hypoglycemia in Type 2 Diabetes: Increased Risk or Protection in SARS-CoV-2 Infection?
منشور في 2021"…<h3>Introduction</h3><p dir="ltr">Neuropilin-1(NRP1) is a cofactor that enhances SARS-CoV-2 coronavirus cell infectivity when co-expressed with angiotensin-converting enzyme 2(ACE2). …"