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Insights Into SARS-CoV-2 S1-RBD-ACE2 Interaction Using Computational Tools and Membrane Microarray Platform
Published 2024“…This revealed clustering of S1-RBD on membrane and more importantly, a depletion of the Omicron S1-RBD from membrane corrals, which was not seen with the WT S1-RBD. Further, treatment of cells with pitstop2, but not blebbistatin, resulted in a decrease in the S1-RBD depletion. …”
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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
Published 2025“…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…”
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SARS‐CoV‐2 infection triggers more potent antibody‐dependent cellular cytotoxicity (ADCC) responses than mRNA‐, vector‐, and inactivated virus‐based COVID‐19 vaccines
Published 2024“…Notably, omicron infection showed reduced overall ADCC activity compared to WT SARS‐CoV‐2 infection. Although post‐mRNA vaccination BTI elicited high levels of binding and NAbs, ADCC activity was significantly reduced. …”
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Dynamics of Neisseria gonorrhoeae transmission among female sex workers and clients: A mathematical modeling study
Published 2024“…Increasing symptomatic treatment coverage among FSWs from 0 % to 100 % decreases prevalence from 10.6 % to 4.5 %, 0.8 % to 0.4 %, and 0.3 % to 0.1 %, respectively. …”
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Aortic valve function post-replacement of severe aortic stenosis by transcatheter procedure versus surgery: a systematic review and metanalysis
Published 2021“…TAVR was associated with 37% (95% CI [0.51–0.78) mean RR reduction of post-procedural PPM, a decrease that was not affected by the surgical risk at inclusion, neither by the transcatheter heart valve system. …”
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Impact of aluminium acetate particles size on the gelation kinetics of polyacrylamide‐based gels: Rheological and molecular simulation study
Published 2023“…The addition of bentonite at low crosslinker concentrations (0.5–1 wt.%) did not decrease the gel strength of 7 wt.% PAM/1 wt.% AlAc significantly. …”
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Corrosion Evaluation of 316L Stainless Steel Exposed to CNT-Water Nanofluid
Published 2019“…The electrochemical testing was performed at different CNTs loadings of 0.05, 0.1, 0.3 and 0.5 wt.% that were suspended in deionized water using the surfactant Gum Arabic (GA). …”
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Thermally Conductive Polyethylene/Expanded Graphite Composites as Heat Transfer Surface: Mechanical, Thermo-Physical and Surface Behavior
Published 2020“…Moreover, the surface wettability of the HDPE/EG composite was enhanced by corona and RF plasma treatment as demonstrated by the increase in surface free energy from 28.5 mJ/m2 for untreated HDPE/EG to 55.5 and 54.5 mJ/m2 for HDPE/EG treated by corona and RF plasma, respectively. …”
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High-Performance Acetic Acid Sensing Using Cerium-MoS₂ Composite for Beverages and Food Processing Industry
Published 2025“…Furthermore, the repeatability of the Ce<sub>0.6</sub> -MoS<sub>2</sub> sensor was assessed over 30 days, and a marginal decrease of 5% in response was observed from day 1 to day 30.…”
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Production and investigation of flexible nanofibers of sPEEK/PVP loaded with RuO2 nanoparticles
Published 2021“…The samples were synthesized with different concentrations of hydrous ruthenium chloride of 2 wt%, 5 wt%, and 10 wt%, and then annealed at a temperature of 300 °C for 4 h to form the ruthenium oxide nanoparticles. …”
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Improved properties and salt rejection of polysulfone membrane by incorporation of hydrophilic cobalt-doped ZnO nanoparticles
Published 2024“…The hybrid PSf membranes were fabricated with 0.5 wt. % of ZnO and doped ZnO NPs. These membranes were characterized using XRD, TGA, FESEM-EDX, and salt rejection performance. …”
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Interleukin-35 and Thymoquinone nanoparticle-based intervention for liver protection against paracetamol-induced liver injury in rats
Published 2023“…Group IV (PAR) received 600 mg/kg of PAR orally; V (PAR + IL-35) and VI (PAR + TYHO); rats received 600 mg/kg of PAR orally and i.p injection of IL-35 (200 ng/kg) or THYO (0.5 mg/kg), respectively. …”
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Enhanced thermoelectric properties of Bi<sub>2</sub>Te<sub>2.55</sub>Se<sub>0.45</sub> nanocomposites using eco-friendly Eocene Midra Shale palygorskite nanofillers: A sustainable...
Published 2025“…The EMS was obtained from one of Qatar’s substantial hydrocarbon reservoirs and mixed with the Bi2Te2.55Se0.45 alloy using ball-milling and hot-pressing techniques. Different wt% of EMS (0.025, 0.05, 0.1, 0.5, and 1) were considered. …”
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Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis
Published 2025“…</p><h3>Results</h3><p dir="ltr">LAT2KO mice experienced a notable reduction in body weight during fasting (WT:14% and LAT2KO:18%, <i>p</i> = 0.02), with a greater reduction in fat mass (0.5‐fold, <i>p</i> = 0.013) and a higher relative retention of muscle mass (1.3‐fold, <i>p</i> = 0.0003) compared with WT. …”
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Investigating the Role of FOXA2 Transcription Factor in Adipogenesis Using Human-Induced Pluripotent Stem Cells
Published 2025“…Furthermore, mature adipocytes differentiated from <i>FOXA2</i> KO derived MSCs showed elevated apoptosis indicated by the Annexin V staining, lipid accumulation detected by Oil Red O staining, and decreased expression of adipocyte maturation and functional genes utilizing the RT-PCR technique. …”
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The effects of long-term testosterone treatment on endocrine parameters in hypogonadal men: 12-year data from a prospective controlled registry study
Published 2022“…This was accompanied by an increase in estradiol levels by 14.9 pmol/L (<i>p</i> < 0.0001), and decreases in progesterone (0.2 ng/mL, <i>p</i> < 0.0001), LH (10.4 U/L, <i>p</i> < 0.0001) and FSH (8.4 U/L, <i>p</i> < 0.0001) were demonstrated at 12-years. …”
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Combined effects of treated domestic wastewater, fly ash, and calcium nitrite toward concrete sustainability
Published 2021“…Test results revealed that TWW slightly decreased concrete compressive and flexural strengths by 5%–12%, whereas it dramatically increased the porosity and chloride permeability by about 40%. …”
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Enhancing the corrosion resistance of reinforcing steel under aggressive operational conditions using behentrimonium chloride
Published 2019“…Herein, the inhibition efficiency of a new corrosion inhibitor, behentrimonium chloride (BTC, C25H54ClN), is explored in a simulated-concrete pore solution (SCP) with 3.5 wt.% NaCl at different pH using electrochemical impedance spectroscopy (EIS) and polarization methods. …”
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The Effect of Atorvastatin (and Subsequent Metformin) on Adipose Tissue Acylation-Stimulatory-Protein Concentration and Inflammatory Biomarkers in Overweight/Obese Women With Polyc...
Published 2019“…</p><h3>Results</h3><p dir="ltr">There was significant reduction in ASP (156.7 ± 16.2 vs. 124.4 ± 14.8 ng/ml p <0.01), IL-6 (1.48 ± 0.29 vs.0.73 ± 0.34 pg/ml p = 0.01) and MCP-1 (30.4 ± 4.2 vs. 23.0 ± 4.5 pg/ml p = 0.02) after 12 weeks of atorvastatin that was maintained subsequently with 12 weeks treatment with metformin. …”