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Supplementary Material for: Decreasing Attacks and Improving Quality of Life through a Systematic Management Program for Patients with Hereditary Angioedema
Published 2021“…We aimed to investigate the effects of a systematic intervention for HAE patients. …”
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Expression of IR21a, IR93a, and IR25a proteins decreases in DOCCs at the late third instar.
Published 2021“…Right: <i>Ir21a>GFP-</i>labeled DOCCs express IR21a (Fig 4A), IR93a (Fig 4C) and IR25a (Fig 4E) proteins at 72 hr AEL (top), which are significantly decreased at 120 hr AEL (bottom). …”
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Decreased respiratory performance of children and adolescents with myelomeningocele who use a wheelchair – preliminary data
Published 2019“…MMC showed lower values for forced vital capacity, forced expiratory volume at the first second, forced expiratory flow (25–75%), maximal voluntary ventilation, and isometric peak for shoulder flexors and adductors compared to healthy participants. This indicated a decreased vital capacity, respiratory muscle endurance, and shoulder muscle strength.…”
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A randomized trial of a behavioral intervention to decrease hospital length of stay by decreasing bedrest
Published 2020“…Previous studies of early mobilization have demonstrated improvement in outcomes, but the interventions studied have been resource-intensive. We aimed to decrease the time hospital inpatients spend in bed through a pragmatic mobilization protocol.…”
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Extracellular vesicles isolated from patients undergoing remote ischemic preconditioning decrease hypoxia-evoked apoptosis of cardiomyoblasts after isoflurane but not propofol expo...
Published 2020“…Hypoxia increased apoptosis of H9c2 cells (hypoxia: 8.4%±0.6; normoxia: 2.5%±0.1; p<0.0001). …”
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Image_3_A decrease in Fkbp52 alters autophagosome maturation and A152T-tau clearance in vivo.TIF
Published 2024“…<p>The failure of the autophagy-lysosomal pathway to clear the pathogenic forms of Tau exacerbates the pathogenesis of tauopathies. We have previously shown that the immunophilin FKBP52 interacts both physically and functionally with Tau, and that a decrease in FKBP52 protein levels is associated with Tau deposition in affected human brains. …”
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Table_1_A decrease in Fkbp52 alters autophagosome maturation and A152T-tau clearance in vivo.DOCX
Published 2024“…<p>The failure of the autophagy-lysosomal pathway to clear the pathogenic forms of Tau exacerbates the pathogenesis of tauopathies. We have previously shown that the immunophilin FKBP52 interacts both physically and functionally with Tau, and that a decrease in FKBP52 protein levels is associated with Tau deposition in affected human brains. …”
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Image_2_A decrease in Fkbp52 alters autophagosome maturation and A152T-tau clearance in vivo.TIF
Published 2024“…<p>The failure of the autophagy-lysosomal pathway to clear the pathogenic forms of Tau exacerbates the pathogenesis of tauopathies. We have previously shown that the immunophilin FKBP52 interacts both physically and functionally with Tau, and that a decrease in FKBP52 protein levels is associated with Tau deposition in affected human brains. …”
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Video_2_A decrease in Fkbp52 alters autophagosome maturation and A152T-tau clearance in vivo.AVI
Published 2024“…<p>The failure of the autophagy-lysosomal pathway to clear the pathogenic forms of Tau exacerbates the pathogenesis of tauopathies. We have previously shown that the immunophilin FKBP52 interacts both physically and functionally with Tau, and that a decrease in FKBP52 protein levels is associated with Tau deposition in affected human brains. …”
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Video_3_A decrease in Fkbp52 alters autophagosome maturation and A152T-tau clearance in vivo.AVI
Published 2024“…<p>The failure of the autophagy-lysosomal pathway to clear the pathogenic forms of Tau exacerbates the pathogenesis of tauopathies. We have previously shown that the immunophilin FKBP52 interacts both physically and functionally with Tau, and that a decrease in FKBP52 protein levels is associated with Tau deposition in affected human brains. …”
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Image_1_A decrease in Fkbp52 alters autophagosome maturation and A152T-tau clearance in vivo.TIF
Published 2024“…<p>The failure of the autophagy-lysosomal pathway to clear the pathogenic forms of Tau exacerbates the pathogenesis of tauopathies. We have previously shown that the immunophilin FKBP52 interacts both physically and functionally with Tau, and that a decrease in FKBP52 protein levels is associated with Tau deposition in affected human brains. …”