Effect of 5-HTR blockade on cost-based motivation. by Yukiko Hori (299784)

Subjects:

Primary endpoint analysis, i.e., time to first occurrence of combined event of 50% decrease in eGFR or ESRD. by Rozita Mohd (7411322)

Table_1_FMT intervention decreases urine 5-HIAA levels: a randomized double-blind controlled study.DOCX by Lihong Wang (14991)

Predictions of random forests (RF), gradient boosting machines (GBM), and neural networks (NN) trained on 12 covariates chosen using subjective feature selection. by Dennis Ochola (11626912)

Predictions of random forests (RF), gradient boosting machines (GBM), and neural networks (NN) trained on 17 covariates selected after recursive feature selection. by Dennis Ochola (11626912)

OPG147 has no effect on TBK1 or IRF3-mediated ISRE activation and HT-DNA-induced signaling. by Xue-Mei Yi (18851202)

Synthesis and Biological Evaluation of Peripheral 5HT_2B Antagonists for Liver Fibrosis by Jihyeon Yoon (8705706)

“…Recent studies have shown that antagonizing 5-hydroxytryptamine receptor 2B (5HT_2B) stimulates the apoptosis of activated hepatic stellate cells and inhibits their proliferation while concurrently regressing hepatocyte proliferation. …”

Synthesis and Biological Evaluation of Peripheral 5HT_2B Antagonists for Liver Fibrosis by Jihyeon Yoon (8705706)

“…Recent studies have shown that antagonizing 5-hydroxytryptamine receptor 2B (5HT_2B) stimulates the apoptosis of activated hepatic stellate cells and inhibits their proliferation while concurrently regressing hepatocyte proliferation. …”

Effect of 5-HTR blockade on reaction time in the work/delay task. by Yukiko Hori (299784)

Subjects:

Effect of 5-HTR blockade on error pattern in the reward-size task. by Yukiko Hori (299784)

Subjects:

Effect of 5-HTR blockade on error pattern in the work/delay task. by Yukiko Hori (299784)

Subjects:

Effect of 5-HTR blockade on reaction time in the reward-size task. by Yukiko Hori (299784)

Subjects:

Effect of 5-HTR blockade on reaction time in the work/delay task. by Yukiko Hori (299784)

Subjects:

Affinity analysis results (with a confidence level above 50%). by Marta R. Jabłońska (8491404)

No discernible effect of high-dose 5-HT_2AR blockade on error rates in the reward-size task. by Yukiko Hori (299784)

Subjects:

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”

Inhibiting translation in 5-HT neurons does not recapitulate a <i>Minute</i> phenotype. by Lisa Patricia Deliu (13570709)

PPM1A facilitates both nuclear distribution and transcription potency of YAP/TAZ. by Ruyuan Zhou (10197187)

“…<b>(B–D)</b> Transcription potency of YAP (5 ng), which was suppressed by coexpression of MST1 (50 ng) (B), LATS1 (500 ng) (C), or MAP4K1 (50 ng) (D), was markedly recovered by cotransfection of wild-type PPM1A but not the enzyme-dead PPM1A (D239N). …”

Effects of FCCP and verapamil on MMP of T47D and HT29 cancer cells. by Jin Won Park (2901029)