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Decreased phosphodiesterase activities in cardiac hypertrophy
Published 2007“…There is limited information on the changes in cardiac cyclic nucleotide phosphodiesterases (PDE1 to PDE5) during hypertrophy and the functional consequences on the cAMP pathway. …”
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Modulation of SLFN11 induces changes in DNA Damage response in breast cancer
Published 2023“…The use of a CRISPR-dCas9 UNISAM and KRAB system could increase or decrease SLFN11 expression significantly (up to fivefold), stably and specifically in BT-549 and T47D cancer cell lines. …”
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A 28 nm CMOS 10 bit 100 MS/s Asynchronous SAR ADC with Low-Power Switching Procedure and Timing-Protection Scheme
Published 2021“…The proposed ADC is fabricated in a 28 nm CMOS process with an active area of 0.026 mm2. …”
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DNA methylation signature in peripheral blood reveals distinct characteristics of human X chromosome numerical aberrations
Published 2015“…The X inactivation process appears to be less effective in Klinefelter syndrome as methylation on the X was decreased compared to normal female samples. In a large number of individuals, we verified several loci by pyrosequencing and observed only weak inter-loci correlations between the verified regions. …”
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The ortholog of human ssDNA-binding protein SSBP3 influences neurodevelopment and autism-like behaviors in <i>Drosophila melanogaster</i>
Published 2023“…One such gene is the single-stranded DNA-binding protein 3 (<i>SSBP3</i>) and its Drosophila melanogaster ortholog is called sequence-specific single-stranded DNA-binding protein (<i>Ssdp</i>). …”
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Proteomics Analysis of Human Obesity Reveals the Epigenetic Factor HDAC4 as a Potential Target for Obesity
Published 2013“…Thrombospondin 1 (TSP1) was among the proteins that were upregulated in obese subjects and then decreased by physical exercise. Conversely, the histone deacetylase 4 (HDAC4) was downregulated in obese subjects and then induced by physical exercise. …”
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The Photocatalytic Degradation of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin in the Presence of Silver–Titanium Based Catalysts
Published 2020“…On the other hand, a decrease in toxicity was observed for the samples with the highest 2,3,7,8-TCDD degradation, confirming that AgTiY irradiated at 302 nm is an excellent choice for degrading TCDD. …”
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Effects of vitamin E derivatives on the proliferation of KG-1 leukemic cells in vitro
Published 2017“…Since the observed decrease in proliferation could also be due to cell cycle arrest, flow cytometry was used to quantify the number of cells in the various phases of cell cycle upon treatment with vitamin E derivatives: cells were stained with propidium iodide and DNA content quantification was performed using the C-flow software. …”
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GSTP1 and NQO1 polymorphisms as risk indicators of lung cancer in Lebanon. (c2006)
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Methylation at global LINE-1 repeats in human blood are affected by gender but not by age or natural hormone cycles
Published 2011“…In this study, we investigated whether this variability could be influenced by age or sex hormones in humans. …”
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Aortic valve function post-replacement of severe aortic stenosis by transcatheter procedure versus surgery: a systematic review and metanalysis
Published 2021“…TAVR was associated with 37% (95% CI [0.51–0.78) mean RR reduction of post-procedural PPM, a decrease that was not affected by the surgical risk at inclusion, neither by the transcatheter heart valve system. …”
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Altered regulation of cell migration in IRF6-mutated orofacial cleft patients-derived primary cells reveals a novel role of RhoGTPases in cleft/lip palate development
Published 2021“…However, a significant decrease in the migratory and adhesion ability of the VWS patient cells was detected compared to the control, which could account for the phenotype. …”
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Nanospace engineering of KOH activated car
Published 2011“…High specific surface areas, porosities, sub-nanometer (<1 nm) and supra-nanometer (1–5 nm) pore volumes are quantitatively controlled by a combination of KOH concentration and activation temperature. …”
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Production and investigation of flexible nanofibers of sPEEK/PVP loaded with RuO2 nanoparticles
Published 2021“…Scanning electron microscopy (SEM) demonstrated the successful fabrication of nanofibers with diameter range of 140–240 nm as well as nanoparticles with average sizes within the range of 6 nm and 9 nm. …”
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High-Performance Acetic Acid Sensing Using Cerium-MoS₂ Composite for Beverages and Food Processing Industry
Published 2025“…Furthermore, the repeatability of the Ce<sub>0.6</sub> -MoS<sub>2</sub> sensor was assessed over 30 days, and a marginal decrease of 5% in response was observed from day 1 to day 30.…”
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Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling
Published 2019“…SNG treatment of MM cells resulted in a dose-dependent decrease in cell viability through mitochondrial membrane potential loss and activation of caspase 3, 9, and cleavage of PARP. …”
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Aqueous urtica dioica leaves extract inhibits proliferation of acute myeloid leukemia cells in vitro
Published 2017“…The decrease was more significant after 72hr with an IC50 at 16mg/ml. …”
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Hippocampal Programmed Cell Death after Status Epilepticus
Published 2003“…Methods: In adult rats, KA-induced SE resulted in DNA fragmentation documented at 30 h after KA injection. …”
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