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Cost-Benefit Analysis of Antimicrobial Stewardship Program in the Adult General Medicine Setting in Qatar
Published 2024“…<h3>Background</h3><p dir="ltr">There is a lack of evidence regarding the economic impact of antimicrobial stewardship program (ASP).We sought to evaluate the cost-benefit of the mature ASP use compared to premature ASP use in the adults’ general medicine settings in Qatar. …”
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182
Trends in prevalence of blindness and distance and near vision impairment over 30 years: an analysis for the Global Burden of Disease Study
Published 2020“…Globally, between 1990 and 2020, among adults aged 50 years or older, age-standardised prevalence of blindness decreased by 28·5% (–29·4 to −27·7) and prevalence of mild vision impairment decreased slightly (–0·3%, −0·8 to −0·2), whereas prevalence of moderate and severe vision impairment increased slightly (2·5%, 1·9 to 3·2; insufficient data were available to calculate this statistic for vision impairment from uncorrected presbyopia). …”
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183
α-ketoglutarate (αKG) acts as a protective factor against chronic stress and has antidepressant properties by modulating BDNF levels in the brain
Published 2022“…In the hippocampus, aKG increases BDNF levels possibly through the PGC1a-BDNF pathway. In the NAc, aKG decreases BDNF levels possibly through the FNDC5-BDNF pathway.…”
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184
Reduced graphene aerogels as energy efficient selective oil sorbents
Published 2022“…The gases used to reduce graphene oxide aerogel are H<sub>2</sub> and N<sub>2</sub> with an optimized ratio of 5:95. The presence of H<sub>2</sub> significantly decreased the oxygen-containing functional groups in graphene aerogel. …”
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185
TCAD Simulation and Analysis of Selective Buried Oxide MOSFET Dynamic Power
Published 2019“…Increasing power dissipation may lead to decreasing system effciency and lifetime. The BULK metal oxide semiconductor field-effect transistor (MOSFET) has relatively high power dissipation and low frequency response due to its internal capacitances. …”
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186
Clinical characteristics and outcome of children with acute cryptorchid testicular torsion: A single-center, retrospective case series study
Published 2024“…</p><p><br></p><h3>Results</h3><p dir="ltr">We found eight patients with unilateral acute cryptorchid TT with a prevalence of 8.9% (8/90) among all TT cases. …”
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187
Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
Published 2008“…WP1066 achieved an IC50 of 1.6 μM, 2.3 μM, and 1.5 μM against the human melanoma cell line A375, murine melanoma cell line B16, and B16EGFRvIII, respectively. …”
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188
Differences in protein expression, at the basal state and at 2 h of insulin infusion, in muscle biopsies from healthy Arab men with high or low insulin sensitivity measured by hype...
Published 2023“…Among the 835 proteins, two showed differential responsiveness to insulin; ATP5F1 protein was decreased, and MYLK2 was higher in the LIS group compared with that in the HIS group. …”
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189
Hepatitis serology predicts tumor and liver-disease characteristics but not prognosis after resection of hepatocellular carcinoma
Published 2004“…Using a multicenter international database, we identified 446 patients with complete HBV and HCV serology. …”
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Marine Bacterial Community Structures of Selected Coastal Seawater and Sediment Sites in Qatar
Published 2023“…<i>Alphaproteobacteria</i> (33.87%, 16.82%),<i> Flavobacteria</i> (30.68%, 5.84%), and Gammaproteobacteria (20.35%, 12.45%) were abundant at the species level in both seawater and sediment, while <i>Clostridia</i> (13.72%) was abundant in sediment only. …”
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193
Glycemic outcomes of Advanced Hybrid Closed Loop system in children and adolescents with Type 1 Diabetes, previously treated with Multiple Daily Injections (MiniMed 780G system in...
Published 2022“…</p><h3>Methods</h3><p dir="ltr">In this prospective open label single-arm, single-center, clinical investigation, we recruited children and adolescents (aged 7–17 years) with T1D on MDI therapy and HbA1c below 12.5%. …”
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Temporal patterns of cancer burden in Asia, 1990–2019: a systematic examination for the Global Burden of Disease 2019 study
Published 2024“…Tracheal, bronchus, and lung cancer (both sexes), breast cancer (among females), colon and rectum cancer (both sexes), stomach cancer (both sexes) and prostate cancer (among males) were among top-5 cancers in most Asian countries in terms of ASIR and ASMR in 2019 and cancers of liver, stomach, hodgkin lymphoma and esophageal cancer posted the most significant decreases in age-standardized rates between 1990 and 2019. …”
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Sulforaphane Delays Fibroblast Senescence by Curbing Cellular Glucose Uptake, Increased Glycolysis, and Oxidative Damage
Published 2018“…The mechanism of cell senescence delay and connection between these responses is unknown. We describe herein that the cruciferous vegetable-derived metabolite, sulforaphane (SFN), activates Nrf2 and delays senescence of human MRC-5 and BJ fibroblasts in vitro. …”
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196
Therapeutic targeting of the TPX2/TTK network in colorectal cancer
Published 2023“…The growth potential of CRC cells under 3-dimensional (3D) conditions was assessed using Matrigel. STRING database (v11.5) and Ingenuity Pathway Analysis (IPA) tool were used for network and pathway analyses. …”
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197
Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants
Published 2017“…Global age-standardised prevalence of raised blood pressure was 24·1% (21·4–27·1) in men and 20·1% (17·8–22·5) in women in 2015. Mean systolic and mean diastolic blood pressure decreased substantially from 1975 to 2015 in high-income western and Asia Pacific countries, moving these countries from having some of the highest worldwide blood pressure in 1975 to the lowest in 2015. …”
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Hippocampal Programmed Cell Death after Status Epilepticus
Published 2003“…To investigate potential mechanisms that may underlie SE-related neuronal injury, we studied the occurrence of programmed cell death (PCD) in the hippocampus in the kainic acid (KA) model. …”
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A Multidecadal Assessment of Haze Development and Fluctuations in Visibility for Arabian Peninsula
Published 2024“…To comprehend the time-based patterns of visibility across the ME, we utilized the Mann Kendall (MK) and Modified Mann Kendall (MMK) trend estimators in both space and time. …”
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An additive manufacturing approach based on electrohydrodynamic printing to fabricate P3HT:PCBM thin films
Published 2023“…<p dir="ltr">Additive manufacturing (AM) enables the production of high value and high performance components with applications from aerospace to biomedical fields. We report here on the fabrication of poly(3-hexylthiophene): phenyl-C61-butyric acid methyl ester (P3HT:PCBM) thin films through the electrohydrodynamic atomization (EHDA) process and its integration as absorber layer for organic solar cells. …”