Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients حسب Al-Amleh, Esraa K.

"…Platelet counts, on the other hand, dramatically decreased in both IM and (HU + IM). (4) Conclusion: Because the studied genes (BCL2, PP2A, CIP2A, and WT1) are participating in cell proliferation and death, the findings show that the examined genes are significant to understand the efficacy of various therapies. …"
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Dynamic workload patterns prediction for proactive auto-scaling of web applications حسب Iqbal W.

"…The framework is implemented and experimentally evaluated using historical access logs of three real web applications, each with increasing, decreasing, periodic, and randomly varying arrival rate behaviors. …"
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Decreased soil moisture due to warming drives phylogenetic diversity and community transitions in the tundra حسب Scharn, Ruud

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Oral PTCTS (Particulated Transialidase) Removes Serum Microparticles and Decreases Inflammation in Atherosclerotic Plaques of Rabbits حسب Garavelo, Sherrira M.

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Quality improvement can decrease blood delivery turnaround time: Evidence from a single tertiary-care academic medical center حسب Hammad Y.A.

"…Settings and Design: This before-after study assessed blood delivery TAT at our institution at baseline (first audit, December 2015 - February 2016); analyzed the causes of any delays and implemented a multipronged organizational, educational and operational remedial actions for risk mitigation for 3 months, aiming to shorten the blood delivery TAT; and then 9 months later assessed the blood delivery TAT again (second audit, November 2017 - December 2017). …"
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apoA2 correlates to gestational age with decreased apolipoproteins A2, C1, C3 and E in gestational diabetes. حسب Ramanjaneya, Manjunath

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Imatinib‑ and ponatinib‑mediated cardiotoxicity in zebrafish embryos and H9c2 cardiomyoblasts حسب ZAKARIA, ZAIN Z

"…This comprehensive approach, utilizing both in vitro and in vivo models alongside functional and molecular analyses, provides a robust assessment of the potential cardiotoxic effects. TKI exposure decreased viability and surface area in H9c2 cells in a dose‑dependent manner. …"
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Lipid-lowering therapies for atherosclerosis: Statins, fibrates, ezetimibe and pcsk9 monoclonal antibodies حسب Ali, A.H.

"…This study focuseson the more recent molecular and genetic interventions exemplified by proprotein convertase subtilisin/kexin type 9 (PCSK9) monoclonal antibodies, evinacumab, and microRNA inhibitors. …"
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Impact of Genetic Polymorphisms on Phenytoin Pharmacokinetics and Clinical Outcomes in the Middle East and North Africa Region حسب Dagenais, Renée

"…Appreciable variability in minor allele frequencies existed both between and within countries of the Middle East and North Africa region. Conclusions CYP2C9 decrease-of-function alleles altered phenytoin pharmacokinetics in patients originating from the Middle East and North Africa region. …"
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Trends in prevalence of depression and anxiety symptoms and effects of sociodemographic variables before and after the first wave of COVID-19 in Qatar حسب Khaled, Salma M.

"…Methods We conducted a trend analysis using repeated nationally representative cross-sectional surveys spanning 2017, 2018, 2020/2021 and using the Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorder-7 (GAD-7) to assess depressive and anxiety symptoms. …"
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Bio-Inspired Fabrication of Ultrafiltration Membranes Incorporating Polydopamine Functionalized Graphene Oxide Nanoparticles حسب Alkhouzaam, Abedalkader I.

"…Thus, the flux increased with the embedding of rGO-PDA without affecting the rejection properties, while it decreased with the embedding of pristine GO. The highest pure water permeability (PWP) was obtained with PSF/rGO PDA-0.1 to be approximately twice that of the pristine PSF and PSF/GO-0.1. …"
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Effect of recombinant human erythropoietin and doxorubicin in combination on the proliferation of MCF-7 and MDA-MB231 breast cancer cells حسب Radwan, Esam M.

"…In order to confirm apoptosis in the doxorubicin-treated cells, the activities of caspases-3/7 and ‑9 were determined using a TBE assay. The results indicated that the activities of caspases-3/7 and ‑9 were significantly elevated in the doxorubicin-treated MDA-MB-231 cells by 571 and 645%, respectively, and in the MCF 7 cells by 471 and 345%, respectively, compared with the control cells. …"
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In vitro evaluation of Neosetophomone B inducing apoptosis in cutaneous T cell lymphoma by targeting the FOXM1 signaling pathway حسب Kuttikrishnan, Shilpa

"…Objective: In this study, we investigated the anti-cancer potential of Neosetophomone B (NSP-B), a fungal-derived secondary metabolite, on CTCL cell lines H9 and HH. Methods: Cell viability was measured using Cell counting Kit-8 (CCK8) assays. …"
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Optimization of performance and emission characteristics of CI engine fueled with Jatropha biodiesel produced using a heterogeneous catalyst (CaO) حسب Singh, A.

"…The heterogeneous transesterification delivered a yield of 81.6% at 5 wt% catalyst concentration and 12:1 methanol to oil molar ratio. …"
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ELECTRODE SUSPENSION FOR AQUEOUS SODIUM FLOW BATTERY حسب MESLAM, MENTALLAH MOHAMED HASSANIN MOHAMED HASSANIN

"…At 1.5 wt% KB, the anolytes could tolerate high load (25 wt%) of NTO without severe rise in the rigidity and conductivity under static and flow modes. …"
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Production and investigation of flexible nanofibers of sPEEK/PVP loaded with RuO2 nanoparticles حسب Chamakh, Mariem

"…Scanning electron microscopy (SEM) demonstrated the successful fabrication of nanofibers with diameter range of 140-240 nm as well as nanoparticles with average sizes within the range of 6 nm and 9 nm. The effect of annealing and RuO2 addition was illustrated by the decrease in fibers diameter. …"
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Influence of nitrogen doping on the electrocatalytic activity of Ni-incorporated carbon nanofibers toward urea oxidation حسب Barakat, Nasser A.M.

"…However, the electrochemical measurements indicated that the content of the urea in the initial electrospun solution should be optimized as the results showed that the best nickel surface activation as well as the maximum observed current density can be achieved when the urea content is kept at 5 wt%. Typically, the observed current densities using 1.0 M urea (in 1 M KOH) were 3.15, 29.7, 13.75, 47.55, 14.13 and 9.85 mA/cm2 for the nanofibers obtained from electrospun solutions having 0, 1, 2, 5, 7 and 9 wt% urea, respectively. …"
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Development of pH-Controlled Aluminum-Based Polymeric Gel for Conformance Control in Sour Gas Reservoirs حسب Shamlooh M.

"…The results reveal that aluminum acetate, among the screened salts, has a controllable gelation time at pH conditions between 3.5 and 8.5 and is the most stable in the temperature range 25–100 °C. …"
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Comparison of fosfomycin against fluoroquinolones for transrectal prostate biopsy prophylaxis: an individual patient-data meta-analysis حسب Roberts M.J.

"…Methods: An electronic search within literature databases including EMBASE and Web of Science (all databases) for articles assessing TAP as an approach to TRUSPB prophylaxis was conducted. …"
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Artificial weathering and accelerated heat aging studies on low-density polyethylene (Ldpe) produced via autoclave and tubular process technologies حسب Luyt, A. S.

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