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Decreased phosphodiesterase activities in cardiac hypertrophy
منشور في 2007"…Increased heart weight (43%) in the H group was accompanied by a general decrease in PDE activities in LV and a ≈ 50% reduction in PDE3 and PDE4. …"
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neurons
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Flow Simulations of Axisymmetric Prolate Particles in a Cylindrical Pore
منشور في 2015احصل على النص الكامل
doctoralThesis -
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Modulation of SLFN11 induces changes in DNA Damage response in breast cancer
منشور في 2023"…<h3>Background</h3><p dir="ltr">Lack of Schlafen family member 11 (SLFN11) expression has been recently identified as a dominant genomic determinant of response to DNA damaging agents in numerous cancer types. …"
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A CFD- RSM study of cuttings transport in non-Newtonian drilling fluids: Impact of operational parameters
منشور في 2022"…The current article provides a theoretical study of the impact of three operational parameters on cuttings transport in non-Newtonian drilling fluids. …"
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Comparative proteomic analysis of a Candida albicans DSE1 mutant under filamentous and non-filamentous conditions
منشور في 2014"…The DSE1 mutant was shown to lack the chitin biosynthesis protein Chs5, explaining the previously observed decrease in chitin biosynthesis. The wild-type strain expressed Pra1, involved in pH response and zinc acquisition, Atg15, a lipase involved in virulence, and Sod1, required for oxidative stress tolerance, in addition to proteins involved in protein biosynthesis, explaining the increase in total protein content observed compared to the mutants strain. …"
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Resource recovery through bioremediation of fuel-synthesis wastewater in a biofilm photobioreactor using purple non-sulfur bacteria: A circular bioeconomy approach
منشور في 2024"…<p dir="ltr">In the current era of wastewater treatment, integrating reusable water production with resource recovery is a key goal. This study aims to treat fuel-synthesis wastewater (FSW), intending to recover various resources, including polyhydroxybutyrate (PHBs), single cell protein, bacteriochlorophylls, carotenoids, and coenzyme Q10 from suspended and biofilm growth to decrease the harvesting costs. …"
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Prevalence, correlates and management of hyperglycemia in diabetic non-critically Ill patients at a tertiary care center in Lebanon
منشور في 2019"…Objective: The study aims to examine the prevalence of hyperglycemia and assess the correlates and management of hyperglycemia in diabetic non-critically ill patients. Methods: The study was conducted on the medical wards of a tertiary care teaching hospital in Lebanon. …"
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Effective non-intrusive load monitoring of buildings based on a novel multi-descriptor fusion with dimensionality reduction
منشور في 2020"…The latter can not only reduce feature dimensionality, but it can also effectively decrease the intra-class distances and increase the extra-class distances of appliance features; and (iii) a powerful decision bagging tree classifier is implemented to accurately classify electrical devices using the reduced features. …"
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Decreased Expression and Activity of cAMP Phosphodiesterases in Cardiac Hypertrophy and Its Impact on β-Adrenergic cAMP Signals
منشور في 2009"…The inotropic response to maximal β-adrenergic stimulation was reduced by ≈54% in isolated hypertrophied hearts, along with a ≈32% decrease in subsarcolemmal cAMP levels in hypertrophied myocytes. …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…In aged HSA-mUCP1 mice, urinary MG-derived AGEs/FL ratio was decreased ca. 60% whereas there was no change in CML/FL ratio – a marker of oxidative damage. …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…In aged HSA-mUCP1 mice, urinary MG-derived AGEs/FL ratio was decreased ca. 60% whereas there was no change in CML/FL ratio – a marker of oxidative damage. …"
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Heart Rate Variability Analysis Reveals a Non-monotonic Relationship between Humanin Concentration and Cardiac Autonomic Regulation
منشور في 2022"…A mitohormetic type of relationship was observed with HRV features increasing and then decreasing with increasing HN concentration. …"
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