Inhibition of alpha-synuclein seeded fibril formation and toxicity by herbal medicinal extracts by Mustafa T. Ardah (4858657)

“…In order to investigate the inhibitory mechanisms of these two compounds towards fibril formation, we demonstrated that salvianolic acid B binds predominantly to monomers, while dihydromyricetin binds to oligomeric species and to a lower extent to monomers. Remarkably, these two compounds stabilized the soluble non-toxic oligomers lacking β-sheet content after subjecting them to proteinase K digestion.…”

Essays on Digital Financial Inclusion and Financial Resilience for Sustainable Development in Sub-Saharan Africa by Jamila Abubakar (22653059)

“…Women, younger people, and people at lower salaries show less volatile savings. Evidence of a more significant impact of non-food shocks on volatility and dissavings for the sub-groups is revealed. …”

Efficacy and safety of using Etelcalcetide for controlling secondary hyperparathyroidism by Tarek Fouda (18472476)

“…<h3>Background</h3><p dir="ltr">In Qatar, secondary hyperparathyroidism (SHPT) is a common problem in haemodialysis (HD) patients, associated with significant clinical consequences for Chronic Kidney Disease (CKD) patients, including osteitis fibrosa cystica and calcific cardiovascular disease, broadly referred to as CKD–mineral bone disorder. …”

The investigation of treatment design parameters on carbon integration networks by Sabla Y. Alnouri (6331652)

“…The cost of the carbon network increases when the solvent temperatures are increased. However, there was a noticeable linear trend at lower temperatures compared to higher temperatures, where the increase became non-linear. …”

Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar by Doua Abdelrahman (17280667)

“…</p><p> </p></div><h2>Other Information</h2> <p> Published in: Viruses<br> License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3390/v13040540" target="_blank">https://dx.doi.org/10.3390/v13040540</a></p>…”

Masked phenomenon: renal and cardiovascular complications; review and updates by Elmukhtar Habas (14777677)

“…Normal blood pressure should be 120/80 mmHg, which generally decreases when a person is sleeping or sitting. High blood pressure or hypertension occurs when the blood pressure is too high. …”

An ensemble-based machine learning model for predicting type 2 diabetes and its effect on bone health by Belqes Alsadi (18695031)

“…ML models were utilized to distinguish diabetes groups from non-diabetes controls. Recursive feature elimination (RFE) was leveraged to identify a subset of features to improve the performance of model. …”

Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery by Stephen L. Atkin (6684368)

“…Normalization of fasting glucose and HbA1c following bariatric surgery (short-term diabetes remission) was defined as withdrawal of anti-diabetic medication and fasting glucose < 100 mg/dL (5.6 mmol/L) or HbA1c < 6.0%. …”

High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i... by Samar, Shurbaji

“…Conclusion: In comparison to the reference assay, our study demonstrates that Finecare™ exhibits high sensitivity, specificity, agreement, and a strong correlation. These findings provide evidence that Finecare™ is a reliable, valid, and accurate point-of-care test for TSH screening and quantitative measurement, especially in non- or small laboratory settings.…”
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Understanding the Mechanism of Diabetes Mellitus in LRBA-Deficient Patient by Iman Hawari (12561958)

“…However, aggregates related to CD71+ erythroid cells, which have immunosuppressive characteristic, were highly upregulated in the LRBA-deficient patients.Experimental analysis of MIN6 cell in culture revealed that in siRNA-mediated-knockdown of LRBA revealed a significant decreased intracellular proinsulin and mature insulin inside β-cells in comparison so the wild type cells. …”

High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i... by Samar Shurbaji (9938696)

“…Conclusion: In comparison to the reference assay, our study demonstrates that Finecare™ exhibits high sensitivity, specificity, agreement, and a strong correlation. These findings provide evidence that Finecare™ is a reliable, valid, and accurate point-of-care test for TSH screening and quantitative measurement, especially in non- or small laboratory settings.…”