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13901
Table1_Deciphering colorectal cancer radioresistance and immune microrenvironment: unraveling the role of EIF5A through single-cell RNA sequencing and machine learning.docx
Published 2024“…In vivo experiments showed that EIF5A knockdown led to increased infiltration of CD8+ T cells and M1 macrophages, and decreased M2 macrophages and Tregs following radiation therapy, thereby enhancing the radiotherapy response.…”
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13902
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13903
Kidney histologic and functional abnormality in SCA7<sup>140Q/5Q</sup> mice.
Published 2022“…<p>A) Kidney hematoxylin and eosin staining (H&E) of 40-week-old SCA7<sup>140Q/5Q</sup> and WT littermates, B-C) absolute and relative kidney weights, and D) urine Bradford assay results of 28-week-old SCA7<sup><i>140Q/5Q</i></sup> and WT littermates. …”
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13904
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13905
Image_5_Upregulated IL-6 Indicates a Poor COVID-19 Prognosis: A Call for Tocilizumab and Convalescent Plasma Treatment.TIF
Published 2021“…We also found that patients with IL-6 levels, which were 30-fold higher than the normal level, had a poor prognosis compared to patients with lower levels of IL-6.…”
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13906
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13907
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13908
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13909
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13910
Comparison of potential energy minimization curves of hypothetical monomer chains from non-capsid and capsid dimers.
Published 2020“…<p>Compared are apo 3KXS (A) and liganded 5E0I (B) non-capsid chains with the apo T = 4 1QGT capsid chains (C). …”
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13911
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13912
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13913
PS48 partly restores the suppression of LTP by Aβ42.
Published 2022“…<p><b>A</b>. Day 14 rat prefrontal cortex (PFC) exposed to Aβ oligomers (0.5 μM) or Aβ plus PS48 (10 μM). …”
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13914
Assessment of antioxidative capacity and ROS in HK-2 cells following molybdenum treatment and H<sub>2</sub>O<sub>2</sub>-induced oxidative stress.
Published 2024“…(B) Oxidative stress was induced in HK-2 cells with 200 μM H<sub>2</sub>O<sub>2</sub>, and molybdenum was administered at 1, 2, 5, and 10 μg/mL. Molybdenum treatment significantly decreased cellular ROS at all doses (n = 5 per group). …”
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13915
Supplementary Material for: Structural and functional effects of C5aR1 antagonism in a rat model of neonatal hypoxic-ischemic encephalopathy
Published 2024“…Reasoning C5aR1 antagonism can decrease excessive neuroinflammation and thereby improve neurological and functional outcomes, we tested this hypothesis in a rat model of HIE with PMX205, a small molecule that inhibits C5a-C5aR1 interaction. …”
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13916
Relative <i>CHRNA5</i> promoter activity in BE(2)-C cells.
Published 2011“…The deletion (“d” in construct name) or normal (“i” in construct name) allele at rs3841324 is indicated by a red triangle or blue square, respectively. The deletion (“d”) constructs exhibited decreased activity (1.6–2.0-fold) relative to the normal (“i”) constructs. …”
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13917
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13918
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13919
Binding of BDD-FVIII muteins to VWF (A-B) and to BO2C11 (C-G).
Published 2015“…This mutein showed a ~100X faster off-rate and a 28-fold decreased affinity for BO2C11-Fab compared to WT-BDD-FVIII. …”
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13920
Table_1_Sub-Acute Treatment of Curcumin Derivative J147 Ameliorates Depression-Like Behavior Through 5-HT1A-Mediated cAMP Signaling.DOCX
Published 2020“…Background<p>Major depressive disorder (MDD) is a severe mental disorder related to the deficiency of monoamine neurotransmitters, particularly to abnormalities of 5-HT (5-hydroxytryptamine, serotonin) and its receptors. …”