Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Ariadne is a non-hallucinogenic analog in the phenylalkylamine chemical class of psychedelics that is closely related to an established synthetic hallucinogen, 2,5-dimethoxy-4-methyl-amphetamine (DOM), differing only by one methylene group in the α-position to the amine. …”

Dcp1a protein levels are decreased by KapB expression and Torin treatment. by Carolyn-Ann Robinson (13297009)

Illustration of the electrophysiological response (steady-state evoked potential) when stimulating with 8 Hz and 36 Hz in, respectively, a young and an old adult from our sample. by Anna Horwitz (771335)

Subjects:

Diverse stress conditions trigger a rapid and dramatic decrease in miR-520b-3p and a corresponding increase in ATF5 mRNA over time in HeLa cells. by Kari A. Gaither (9046190)

Acetaldehyde decrease/eliminates C/EBP alpha binding to CTSL promoter sequence. by Riyaz A. Mir (350175)

Cardiac overexpression of miR-130a results in decreased FOG-2 expression and a thin ventricular myocardial wall. by Gene H. Kim (371958)

Decreased Muscle Strength of Knee Flexors Is Associated With Impaired Muscle Insulin Sensitivity in Non-Diabetic Middle-Aged Japanese Male Subjects by Yuki Someya (770709)

Substrate translocation via Mep2^H194E induces a pH decrease. by Ana Sofia Brito (8463537)

Inclusion of SRRM4-regulated exons is decreased in tumors and cancer cell lines. by Sarah A. Head (6066398)

“…Red points are exons with PSI decreasing by at least 5% in at least 1 tumor type. …”

Cell viability as measured by MTT absorbance (abs) at 570nm, LDH release and intracellular NAD levels of microglial cells after 48 hour incubation in pooled, non heat inactivated a... by Tharusha Jayasena (704509)

Average awakening citation-intensity <i>c</i>_<i>a</i> for SN-SNPRs and SB-nonSNPRs with <i>s</i> = 5. by Anthony F. J. van Raan (7517696)

Activation of macrophages decreases phagosomal copper availability and impairs proliferation of Ctr3-deficient yeasts. by Qian Shen (89639)

DFT parameters derived for 5, 6a and 6b in their solvated phase using B3LYP functional and 6-31G (d,p) basis set. by Ghadeer Mubarak (21567569)

ND-75^KD flies have reduced mobility, seizures and decreased lifespan. by Lucy Granat (5570813)

MBOAT7 rs641738 (C>T) is associated with NAFLD progression and decreased ASCVD risk in elder Chinese population by Zhang jing (14062485)

Gene silencing of <i>nectin-2</i> decreases GIC susceptibility to NKL cell-mediated cell death. by Fabian Wolpert (803768)

Decreasing HIV viral loads across subdistricts in KwaZulu-Natal province, South Africa, between 2018 and 2022. by Lilishia Gounder (15240167)

Subjects:

EGCG treatment decreases TTR amyloid deposition in the gastrointestinal tract of old hTTR V30M mice. by Nelson Ferreira (188837)

V-ATPase inhibition by archazolid increases the adhesion of MDA-MB-231 cells onto HUVECs and decreases their transendothelial migration. by Betty Luong (5738027)

Both (A) parametric and (B) non-parametric analyses suggest that the bacterial community composition shifts between 5.18 and 7.12 mg O₂ L^-1. by Rachel L. Spietz (782905)