FCF affects HIF-1α expression on the posttranslational level. by Dikla Vardi-Oknin (447319)

“…Quantitative real-time PCR analysis was done using primers for HIF-1α and cyclophilin B as control<i>. Columns</i>, means (n = 2); <i>bars</i>, SD. (<b>B</b>) PC-3 cells were treated with vehicle (control) and 100 μM FCF for 4 h under normoxia, and then CHX was added at a final concentration of 10 μg/ml for the indicated times. …”

The inhibition of mitochondrial respiratory chain complex activity by longer chain TPP⁺ compounds is dose dependent. by Jan Trnka (441288)

“…<p>Samples of rat skeletal muscle homogenate were incubated with various concentrations of decylTPP⁺ and dodecylTPP⁺ prior to the assay. <b>A, B, and C.</b> Complexes I, II, and III show a gradual decrease in activity proportionate with the dose of the TPP⁺ compounds. …”

<i>Mll2^Gdf9</i> cKO oocytes show loss of bulk H3K4me2 and H3K4me3 as well as H4 hyperacetylation. by Claudia V. Andreu-Vieyra (243666)

“…In contrast, a decrease in H3K4me2 (B) and H3K4me3 (C) levels was observed in <i>Mll2^Gdf9</i> cKO oocytes (B and C, lower panels) compared to controls (B and C, upper panels). …”

Supplementary Material for: Carpal Tunnel Surgery as Proxy for Dialysis-Related Amyloidosis: Results from the Japanese Society for Dialysis Therapy by Hoshino J. (4145806)

“…<b><i>Methods:</i></b> The cohort consisted of 166,237 patients on dialysis (mean age 66.1 ± 12.4 years; mean dialysis vintage 7.2 ± 6.4 years) who could be followed for a year between 2010 and 2011. …”

Preincubation with papaverine inhibits norepinephrine (NE) induced contractions in human saphenous vein. by Kyle M. Hocking (402156)

“…Panel B: Cumulative data obtained when the force was converted to stress and decrease in stress was converted to a percentage of the maximal initial KCl contraction which was set as 100%. …”

QTLs for yield and yield-components in F_{2: 3} and F_{2: 4} populations identified using composite interval mapping. by Qingzhi Liang (789537)

“…<p>* Common QTLs identified in the two generations</p><p>^a Additive effects; positive values of the additive effects indicate increase of traits from alleles of GX1135; negative values of the additive effects indicate decrease of traits from alleles of GX100-2</p><p>^b Dominance effects; positive values of the dominance effect indicate that heterozygotes have higher phenotypic values than the respective means of two homozygotes, and negative values indicate that heterozygotes have lower values than the means of the two homozygotes</p><p>^c Var%, phenotypic variation explained by a single QTL</p><p>QTLs for yield and yield-components in F_{2: 3} and F_{2: 4} populations identified using composite interval mapping.…”

Parasitemia titration results. by Paul Lebel (11250722)

“…<p>Logscale plots a-b,d-f contain shaded regions corresponding to nominal mean parasitemia plus or minus one standard deviation of the underlying Poisson distribution when counting N total cells, where N is varied from 100 up to 100,000 in roughly 3× increments. …”

Mechanisms involved in Sag-induced apoptosis. by Juliana Mundiñano (306020)

“…Data are expressed as the mean ± SD. *p<0.05. (E) Caspase-8 inhibitor decreases the loss of Δψm induced by SEB. …”

Effects of diabetes mellitus and systemic arterial hypertension on elderly patients' hearing, by Laurie Penha Rolim (6073727)

“…ANOVA and Kruskal-Wallis statistical tests were used, with a significance level set at 0.05. Results: When comparing the mean annual increase in the auditory thresholds of the A1 with the A2 assessment, considering each study group and its respective control, it can be observed that there was no statistically significant difference for any of the frequencies for the diabetes mellitus group; for the systemic arterial hypertension group, significant differences were observed after 4 kHz. …”

Stable inducible expression of various GFP-coilin proteins with endogenous coilin knockdown. by Zunamys I. Carrero (342815)

“…Rescue indicates that the induced protein increased proliferation in the coilin knockdown background, whereas decrease means the induced protein decreased proliferation rates lower than that found with coilin knockdown alone. …”

PINK1 expression alters mitochondrial function and cellular viability. by Anna Sandebring (263540)

“…Results are expressed as the mean number of cells with TMRM fluorescence above threshold set by depolarizing one set of cells with CCCP (100 µM, 10 minutes; see Supplementary <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0005701#pone.0005701.s001" target="_blank">Fig. …”

PRE, W3, and W6 VL biopsy contractile protein per muscle fiber assessed through phalloidin-AF488 staining. by Cody T. Haun (4183900)

“…This metric was not significantly altered throughout the intervention (panel a). Phalloidin pixel intensity per fiber per μm², which represents actin content corrected for fCSA, demonstrated numerical but non-significant decreases from PRE to W3 and W6 (panel b), although the removal of subject 17 (statistical outlier) indicated a significant decrease occurred from PRE to W6. …”

Glyphosate Resistance Affect the Physiological Quality of Conyza bonariensis seeds by C. PIASECKI (5054501)

“…Seed analyses were performed in a completely randomized design with ten replications of 100 seeds each (1,000 seeds per biotype). …”

Interplay of basolateral K⁺ channels and the Na⁺/K⁺-ATPase. by Alexandra Erb (588278)

“…<b>B</b>) After permeabilisation with nystatin, lidocaine (1 mM) was applied to the basolateral bath. This resulted in a decrease of the I_SC from 17.20±2.58 µA/cm² to 12.00±1.67 µA/cm² (n = 5, N = 5, p≤0.05). …”

HOXA2 control of target enhancers. by Laure Bridoux (481118)

“…Co-translation of HOXA2 with PBX/MEIS gives rise to a stronger trimeric complex relative to HOXA3 and, accordingly, to a decrease in PBX-MEIS binding as a dimer (black arrow; see also <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009162#pgen.1009162.s003" target="_blank">S3G Fig</a> for quantification). …”

Excitation-Transcription (E-T) coupling is altered in dystrophic muscle fibers. by Denisse Valladares (489234)

“…<p>(A) In triad fractions obtained from normal and dystrophic muscles we observed a decrease in the expression of Cav1.1 (antibody against α1 s subunit) and an increase in the expression of Panx1, P2Y2 and P2Y1 in dystrophic compared to normal (n = 4). …”

ER stress reduces AKT phosphorylation at Thr308, but increases it at Ser473, and alters target substrate specificity. by Hong Wa Yung (227056)

“…<b>D</b>) Normalisation between phosphorylated AKT and AKT indicates an increase of Ser473 phosphorylation but a decrease at Thr308.</p>…”

The relative contribution of the different positions in DR2 to the transcriptional strength of P₄ promoter. by Ilia Belotserkovsky (257415)

“…Substitutions of the indicated nucleotides with cytosine or guanine, and increase or decrease of the spacer size by a single nucleotide, were achieved by site-directed mutageneses that were performed on the p<i>P₄-gfp</i> plasmid (see “<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1000651#s4" target="_blank">Materials and Methods</a>”). …”

SipC-mediated invasion occurs independently of cellular Rho GTPases. by Robert J. Cain (272233)

“…Invasion rates after 60 min were compared to wild-type (assigned as 100%). Results are mean±SEM of 4 independent experiments each performed in triplicate. …”

Foxm1 expression during heart development. by Craig Bolte (299486)

“…Mean±SEM was determined from 5 random sections at E14.5 and P7 with 3 hearts in each group. qRT-PCR of total heart RNA demonstrated a decrease in Foxm1 mRNA from E14.5 to P20 and Foxm1 mRNA was undetectable in the adult heart (R). …”