Selectivity of PRMT5 inhibition with C220. by Shelby L. Sloan (10803222)

“…(C) Immunoblots and quantification of three biological replicate experiments, showing attenuated SDMA and H4R3me2s in 17–71 (day 4) and CLBL-1 (day 2) after treatment with 100 nM C220, with no significant decreased to PRMT5 expression. …”

T- and R-type calcium channels modulate glutamate spikes, synaptic and bursting activities. by Saju Balakrishnan (58265)

“…<b><i>E</i>–</b>Miniature EPSCs before and 15 min after addition of calcium channel blockers to the bath (the recordings were made at -70 mV in the presence of 100 nM TTX). <b><i>F</i>–</b>Group summary of blocker effects. …”

CTR-C PDZ- binding motif mutation and TJ disruption and invasion. by Ahmed Aljameeli (2548528)

“…<p>A. Transepithelial Electric Resistance (TER): Polarized PC-3v, PC-3-CTRwt and PC-3CTR-∆ESS cells were serum-starved for 4 hours, then treated with/without 50 nM CT. …”

Simulated training model of ureteropyelic anastomosis in laparoscopic pyeloplasty by Juliana Cynara Santos Lima (10394303)

“…Regarding the knots, in the 1st step, 5% of them were considered firm, with an evolution to 30% in the last step (p = 0.011). …”

Adenine base-pairing and stacking in d(AACCCC) and d(CCCCAA) by Narcisse Esmaili (6648)

“…The structures are shown looking down the helix axis from the 5′ end. The bond widths decrease with the base elevation. () [d(CCCCAA)]: stacking at the C4–A5 step in the 3′E intercalation topology and inter-duplex stacking of C1 between C4 and A5 in the 5′E topology. () [d(AACCCC)]: cross-strand stacking of A1 and A2 and intra-strand stacking at the A2–C3 step.…”

PKA-dependent stellation induces changes in phosphorylation of both profilins. by Stefanie K. Schweinhuber (687289)

“…(D) MOCK transfected astrocytes are significantly more stellate upon forskolin treatment (95.0±3.3%) compared to both PFN1 KD (57.5±10.1%) or PFN2a KD cells (49.4±10.5%). (E) Simultaneous co-application of FSK and the PKA inhibitor KT5720 (KT, 100 nM) abolished the stellation effect of FSK on MOCK transfected cells (MOCK 63.8±7.0%; PFN1 KD 63.8±10.7%; PFN2a KD 63.3±8.0%). …”

UTX-1 is required for VPA action in <i>C. elegans</i> embryos and in human cells. by Rakel Brendsdal Forthun (121022)

“…Numbers shown are arbitrary units compared to negative control siRNA. The blot shows a 60% decrease in UTX by siRNA treatment, confirming the efficacy of transfection. …”

Effect of ACE inhibitors on the local conformation of blood ACE in uremia. by Maxim N. Petrov (118931)

“…<p><b>A</b>. The ratio of ACE activities precipitated from the citrated plasma of uremic patients by mAbs 1G12 and 9B9 (1G12/9B9 ratio) and from pooled plasma from healthy volunteers in the presence of enalaprilat (100 nM) – red bars and without the inhibitor – grey bars. …”

Increasing motor protein stall force and number of heads per minifilament results in clustered actin filaments. by Maria-Veronica Ciocanel (9565099)

“…Unless otherwise indicated above, the parameter values used are <i>d</i>_step = 6 nm, <i>k</i>_head,bind = 0.2/s, <i>F</i>_s = 100 pN, range_heads = 15–30 (see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1010026#pcbi.1010026.t001" target="_blank">Table 1</a>). …”

p17 inhibits CDK1 kinase activity which leads to inhibition of vimentin phosphorylation at Ser 56 and suppression of the association of CDK1-vimentin and Plk1-vimentin. by Hung-Chuan Chiu (780062)

“…In the presence of TrxA-His-p17, the decrease in the level of vimentin-Ser56 phosphorylation was seen in a dose-dependent manner. …”

Effects of optogenetic silencing of MTCs on the patterns of oscillatory activity in the neonatal OB. by Sabine Gretenkord (3572213)

“…(C) Neuronal firing (SUA) and LFP band-pass filtered for different frequency bands (broad 1–100 Hz, RR 2–4 Hz, theta 4–12 Hz) in response to light (yellow, 594 nm) stimulation of MTCs in a P8 cre⁺ Tbet-cre;ArchT-EGFP mouse. …”

Increased aerobic glycolysis in MADD fibroblasts and <i>xav</i> mutants. by Yuanquan Song (238595)

“…<p><b>A.</b> ECAR was measured in intact control and MADD Patient 1 fibroblasts under basal conditions, following the addition of the mitochondrial inhibitor oligomycin (0.5 µg/ml), in the presence of the uncoupler CICCP (3 µM) and following the addition of the complex I inhibitor rotenone (100 nM). …”

ZnO−Al₂O₃ and ZnO−TiO₂ Core−Shell Nanowire Dye-Sensitized Solar Cells by Matt Law (1296396)

“…However, titania shells 10−25 nm in thickness cause a dramatic increase in <i>V</i>_OC and fill factor with little current falloff, resulting in a substantial improvement in overall conversion efficiency, up to 2.25% under 100 mW cm^-2 AM 1.5 simulated sunlight. …”

ADPβS had no effect on two physiologic parameters of Mü ller cell gliosis by Ortrud Uckermann (82321)

“…The currents were measured between the voltage steps to j100 mV and to −160 mV; the holding potential was −80 mV. …”

Oxygen Consumption Rates (OCR) and respiration parameters in Aur treated N27 cells. by Pamela Lopert (114596)

“…<p>N27 cells were treated with 100 nM or 300 nM Aur alone or in combination with 100 µM PQ for 18 hrs. …”

DataSheet1_Enhanced Spin Accumulation in Semiconductor at Room Temperature Using Ni0.65Zn0.35Fe2O4(NZFO) as Spin Injector in NZFO/MgO/p-Si Device.docx by Nilay Maji (9498944)

“…The parameters such as spin lifetime (99 ps), spin diffusion length (276 nm), and spin polarization (0.44) have been estimated from the Hanle curve detected in our heterostructure at room temperature, making the Ni_0.65Zn_0.35Fe₂O₄/MgO/p-Si device a very favorable promising junction structure in the field of spintronics for several device appliances in the future.…”

Evidence for coordinated motion of chromatin domains and PC bodies. by Thierry Cheutin (188737)

“…Each grey line is spaced by 100 nm (B, D, F, H, J, K, M and N).</p>…”

The proteasome inhibitor Bortezomib inhibits not only FANC signaling, but also HR, Alt-EJ, and end resection. by Sean M. Howard (687174)

“…U2OS cells were treated with Bortezomib (100 nM, 4 hr before IR treatment) or vehicle (DMSO) as well as with an individual FANCA siRNA (siFANCA-3) or non-targeting siRNA (siCTRL). …”

Effect of shear, TFPI-coating concentration and FVIIa concentration in MDA-MB-231 adhesion to protein-immobilized channels under shear. by Sara P. Y. Che (718192)

“…</b> Microfluidic channels were immobilized with 100μg/mL TFPI, and MDA-MB-231 cells (pretreated with 10nM or 100nM FVIIa, and 10nM FX) were introduced at a range of shear stresses (0.35–1.3dyn/cm²). …”

Long-term dexamethasone treatment inhibits the induction of <i>ANGPTL4</i> transcription, together with down-regulation of the GR. by Masafumi Nakamoto (3617828)

“…For LTDT, HepG2 cells were initially cultured in DMEM medium supplemented with 10% DCC-treated FBS and 100 nM dexamethasone (Dex) for 14 days. Black arrows show sampling times. …”