Data_Sheet_3_Cardiorespiratory Alterations in a Newborn Ovine Model of Systemic Inflammation Induced by Lipopolysaccharide Injection.PDF by Stéphanie Nault (846680)

“…Two 6-h polysomnographic recordings were performed on two consecutive days on eight full-term lambs: the first after an IV saline injection (control condition, CTRL); the second, after an IV injection of 2.5 μg/kg Escherichia coli LPS 0127:B8 (LPS condition). …”

Data_Sheet_1_The timelines for the price and reimbursement authorization in Italy 2018–2020.pdf by Valentina Gallo (95843)

“…In 2020, the overall process duration for Off-patent pharmaceuticals procedures was equal to 129.8 average days [95% CI: (122.3–137.2)], with a median value of 108.0, whereas for In-patent pharmaceuticals procedures, it was equal to 283.1 average days [95% CI: (267.8–298.5)], with a median value of 284.0. Over time, the trend of the entire duration of the P&R process tended to decrease. …”

An <em>IL28B</em> Genotype-Based Clinical Prediction Model for Treatment of Chronic Hepatitis C by Thomas R. O'Brien (214533)

“…Subjects were re-treated with pegylated-interferon/ribavirin during trial lead-in. We used step-wise logistic regression to calculate adjusted odds ratios (aOR) and create the predictive model. …”

Localization of anti-TG2 scFvs after intraventricular delivery and footprint analysis. by Sabrina Boscolo (251883)

“…Mice treated with monoclonal antibodies were tested at 5 h, after antibody injection for gait imbalance with footprint analysis. …”

Single-molecule properties of the Head1/Neck3 chimera. by Sarah Adio (374199)

“…Motors were observed for 5 sec with an integration time of 200 ms at an ATP concentration of 20 µM. …”

Data_Sheet_2_Cardiorespiratory Alterations in a Newborn Ovine Model of Systemic Inflammation Induced by Lipopolysaccharide Injection.PDF by Stéphanie Nault (846680)

“…Two 6-h polysomnographic recordings were performed on two consecutive days on eight full-term lambs: the first after an IV saline injection (control condition, CTRL); the second, after an IV injection of 2.5 μg/kg Escherichia coli LPS 0127:B8 (LPS condition). …”

DataSheet1_Causal effects and metabolites mediators between immune cell and risk of colorectal cancer: a Mendelian randomization study.docx by Qian Yang (300330)

“…</p>Methods<p>We employed a two-sample bidirectional Mendelian randomization (MR) approach to assess the causal influence of immune cells on CRC. Additionally, a two-step MR strategy was utilized to pinpoint potential metabolites that mediate this effect. …”

The Cellular and Molecular Basis of Bitter Tastant-Induced Bronchodilation by Cheng-Hai Zhang (385288)

“…We show that these Ca²⁺ changes in cells at rest are mediated via activation of the canonical bitter taste signaling cascade (i.e., TAS2R-gustducin-phospholipase Cβ [PLCβ]- inositol 1,4,5-triphosphate receptor [IP3R]), and are not sufficient to impact airway contractility. …”

Data_Sheet_1_Cardiorespiratory Alterations in a Newborn Ovine Model of Systemic Inflammation Induced by Lipopolysaccharide Injection.PDF by Stéphanie Nault (846680)

“…Two 6-h polysomnographic recordings were performed on two consecutive days on eight full-term lambs: the first after an IV saline injection (control condition, CTRL); the second, after an IV injection of 2.5 μg/kg Escherichia coli LPS 0127:B8 (LPS condition). …”

Table1_Impact of the COVID-19 pandemic on antidepressant and antipsychotic use among children and adolescents: a population-based study.docx by Tony Antoniou (215252)

“…Specifically, we observed an immediate step decrease in antidepressant dispensing associated with a structural break in April 2020 (−55.8 units per 1,000 individuals; 95% confidence intervals [CI] CI: −117.4 to 5.8), followed by an increased monthly trend in the rate of antidepressant dispensing of 13.0 units per 1,000 individuals (95% CI: 10.2–15.9). …”

Data_Sheet_1_Estimating the cost of young stock mortality in livestock systems—An application to sheep farming in Ethiopia.PDF by Joachim Otte (232257)

“…</p>Methods<p>The static zero-growth version of DYNMOD was used to calculate the annual physical and monetary output of a sheep flock consisting of 100 breeding females at different levels of lamb mortality. …”

Kinetic characterizations of AChR blockade by PQ1–5. by Wan-Chen Lin (658261)

“…<p>(A) Single-channel currents of the AChR in the presence of 100 µM Ach ±5 µM <b>PQ5</b>. …”

Bacterial Surface Appendages Strongly Impact Nanomechanical and Electrokinetic Properties of <em>Escherichia coli</em> Cells Subjected to Osmotic Stress by Grégory Francius (219120)

“…In 1 mM KNO₃, cells without appendages or cells surrounded by Ag43 exhibit large Young moduli and turgor pressures (∼700–900 kPa and ∼100–300 kPa respectively). Under similar ionic strength condition, a dramatic ∼50% to ∼70% decrease of these nanomechanical parameters was evidenced for cells with appendages. …”

GBE enhanced oxygen consumption of isolated mitochondria and led to an up-regulation of mitochondrial DNA. by Virginie Rhein (243241)

“…<p><b>A</b>) Two-way ANOVA revealed a significant Aβ-induced decrease of the total cellular respiration in isolated mitochondria from APP cells compared to that of control cells (group effect: control vs. …”

<i>In vivo</i> Sema3C treatment prevents O₂-induced arrested vascular growth. by Arul Vadivel (424484)

“…<p>A. Representative photomicrographs showing von Willebrand (vWF) factor staining (brown) in RA (room air), RA+Sema3C, hyperoxia (O₂) and O₂+Sema3C exposed lungs. …”

Transcripts reduced by FRLFE in rat hepatocytes. by Ryota Yamanishi (547533)

“…The mRNA level of IL-1β was set to 100%.</p><p>(+), asRNA was experimentally detected.…”

Involvement of NO, prostacyclin and EDHFs on abacavir-induced relaxation of rat basilar arteries. by Rachel Wai Sum Li (422494)

“…Abacavir-induced relaxation of basilar arteries was then measured. (A) Changes in tension were expressed as the percentage decrease in response to contraction caused by endothelin-1 (ET-1; 1–10 nM). …”

Automobile Accidents in Brazil in 2017: ecological study of the disability-adjusted life years by Tamires Feitosa de Lima (8557440)

“…It is observed, in Brazil, a decrease in death rates (19.68%) and Disability-Adjusted Life Years (22.10%) per automobile accident among individuals of both sexes, between 15 and 49 years, but they are higher than the Global and Southern rates of Latin America. …”

SPP and SKI-1 inhibitors block SARS-S- and MERS-S-driven entry. by Teresa Plegge (4164583)

“…Asterisks indicate a statistical significant decrease (* = p<0.05; ** = p<0.01; *** = p<0.001) of transduction efficiency in the presence of inhibitor compared to DMSO.…”

STAT3 decoy has additionally activity against STAT1. by Jonah D. Klein (505754)

“…<p>(A) HUVECs were transfected with 100 nM of STAT3 decoy oligonucleotide. …”