Action of anandamide (AEA, 400 µM) on planar lipid bilayers: effect of cholesterol. by Eric Di Pasquale (373571)

“…<p><i>A–B</i>. superimposed currents across a bilayer constituted of POPC alone (<i>A</i>), held at 0 mV, in response to a rectangular pulse (+180 mV, 200 ms), before (control, light grey bilayer alone), and after addition of anandamide (heavy grey, +5, +25 min after AEA injection). …”

Spliceosomal particle formation depends on NPC count. by Zhaleh Ghaemi (1507558)

“…<p>Increase (pink) or decrease (blue) in the number NPCs by 20% results in a corresponding change in the number of U1 (A) and U2 (B) particles formed. …”

Destabilization of dystrophin and β-DG by Lis1-Nde1 deficiency. by Ashley S. Pawlisz (52227)

“…<p>(A) Total protein extracts from cerebral cortices of E12.5 embryos were examined by immunoblotting. …”

Dose-related neflamapimod (NFMD) subacute treatment effects on mNSS of rats with tMCAO. by John J. Alam (9732692)

“…In addition, a dose response effect on improvement in neurologic function was indicated by the lower mean±SD mNSS value in the 4.5 mg/kg neflamapimod dose group when compared to that of the 1.5 mg/kg dose group. …”

Regulation of targets by EWS in vivo. by Sujitha Duggimpudi (699551)

“…The linear regression and slopes were calculated and the data is presented as Mean and SEM on a linear scale. <b>E</b>. Luciferase activity of CCDC6 upon EWS transfection (normalized to empty psiCHECK-2 plasmid). …”

Line3-2 reveals lung hypoplasia and limb syndactyly. by Carsten Schnatwinkel (48)

“…<p>(A–H) Embryos dissected at E18.5 (A) reveal that line3-2 mutants are slightly reduced in size and have significantly smaller lung lobes (B–F). …”

Comparative Component Analysis of Exons with Different Splicing Frequencies by Shiqin Song (264631)

“…Beyond the conventional classification for alternatively spliced exons (ASEs) and constitutively spliced exons (CSEs), we have classified exons from alternatively spliced human genes and their mouse orthologs (12,314 and 5,464, respectively) into four types based on their splicing frequencies. …”

The Essential Nucleolar Yeast Protein Nop8p Controls the Exosome Function during 60S Ribosomal Subunit Maturation by Marcia C. T. Santos (215784)

“…Although depletion of Nop8p in yeast cells leads to premature degradation of rRNAs, the biochemical mechanism responsible for this phenotype is still not known. In this work, we show that the Nop8p amino-terminal region mediates interaction with the 5.8S rRNA, while its carboxyl-terminal portion interacts with Nip7p and can partially complement the growth defect of the conditional mutant strain <em>Δnop8/GAL::NOP8</em>. …”

Experimental detection of critical points in fibers treated with blebbistatin. by Fabio C. Minozzo (189129)

“…<p>(A) Superimposed contractions, showing the force decay during shortening while the fiber was activated with pCa²⁺ 4.5- (solid line), and then treated with blebbistatin (dashed line), with the corresponding fiber length changes. …”

Genetic analysis of Japanese primary open-angle glaucoma patients and clinical characterization of risk alleles near <i>CDKN2B-AS1</i>, <i>SIX6</i> and <i>GAS7</i> by Yukihiro Shiga (724428)

“…Among 8 SNPs in 3 loci that showed at least nominal association (<i>P</i> < 5.00E-02) in the primary cohort, a representative SNP for each loci (rs2157719 for <i>CDKN2B-AS1</i>, rs33912345 for <i>SIX6</i>, and rs9913911 for <i>GAS7</i>) were selected. …”

Competition of SP-D binding to gp120 by hexoses. by Jens Madsen (391091)

“…Each trace indicates the response units recorded at a given concentration of SP-D (10, 5, 2.5, 1.25, and 0.625 µg/mL) in 5 mM CaCl₂-containing (HSC) buffer (traces are in order of the highest to lowest concentration). …”

Weight loss following gastric bypass increases aldosterone reactivity to orthostatic stress in patients with obesity by Joachim Zahnd (22169617)

“…At 12 months, mean weight decreased from 126.3 ± 23.2 kg to 116 ± 20.7 kg in the control group and from 120.9 ± 19.4 kg to 78.6 ± 14.0 kg in the RYGB group (<i>p</i> value < 0.01 between groups). …”

Data_Sheet_1_Association of Gut Microbiota With Metabolism in Rainbow Trout Under Acute Heat Stress.docx by Changqing Zhou (175208)

“…In the current study, the optimal growth temperature (16°C) of rainbow trout was used as the control group, while the fish treated at 22.5°C, 23.5°C, and 24.5°C for 24 h, respectively, were the treatment groups. …”

The effect of mycophenolic acid (MPA) and guanosine (Gua) on HCV infectious progeny production and intracellular nucleotide pools. by Ana M. Ortega-Prieto (446894)

“…<p>(a) Huh-7.5 reporter cells were infected with HCVp0 at an initial MOI of 0.1–0.2 TCID₅₀/cell, in the absence or presence of the MPA and Gua concentrations indicated in the upper box. …”

DataSheet_1_Vessel sound causes hearing loss for hummingbird bobtail squid (Euprymna berryi).pdf by Rosalyn L. Putland (5814887)

“…Baseline audiograms indicated that there was a decrease in aural sensitivity with age. All three age groups showed similar, significantly decreased hearing sensitivity following sound exposure, however auditory sensitivity recovered within two hours. …”

DataSheet_1_Vessel sound causes hearing loss for hummingbird bobtail squid (Euprymna berryi).pdf by Rosalyn L. Putland (5814887)

“…Baseline audiograms indicated that there was a decrease in aural sensitivity with age. All three age groups showed similar, significantly decreased hearing sensitivity following sound exposure, however auditory sensitivity recovered within two hours. …”

Visual phenotype of the <i>Fatp1</i>^−/− mouse. by Karim Chekroud (298429)

“…<i>Fatp1^−/−</i> PRs present a lower response to light flashes and this decrease is not due to a decrease in the level of retinal coupled-rhodopsin in these animals.…”

Jet lag adversely impacts PCNA immunostaining and neurogenesis in the dentate gyrus. by Erin M. Gibson (236128)

“…Chronic jet lag resulted in a decrease in neurogenesis by >50% in intact, ADX, and OVX + E₂ hamsters (<i>P = </i>0.01, <i>P = </i>0.007, and <i>P = </i>0.05, respectively; * <i>P<</i>0.05, n = 4/5 animals/group). …”

An Improved PSO Algorithm for Generating Protective SNP Barcodes in Breast Cancer by Li-Yeh Chuang (14936)

“…SNP barcodes containing different numbers of SNPs were computed. The top five SNP barcode results are retained for computing the next SNP barcode with a one-SNP-increase for each processing step. …”

Time dependence of parameter variations necessary to prevent apoptotic state of the system. by Tatiana Baumuratova (499193)

“…<p>Left figure represents analysis of the parameters which values should be increased to prevent apoptosis and right figure shows parameters with necessary decrease in value. A value of variation equal to 0.5 for the left figure and to 1.1 for the right figure indicates that none variation of the certain parameter can prevent apoptosis, i.e. that the parameter has no effect on the system's behavior. …”