Improving osteoarthritis care by digital means - Effects of a digital self-management program after 24- or 48-weeks of treatment by Leif E. Dahlberg (7405928)

“…For the 24-week sub-sample, pain NRS decreased monthly by -0.43 units (95% CI -0.51, -0.35, mean knee pain from 5.6 to 3.1, and hip pain from 5.9 to 3.8) and 30CST repetitions increased monthly by 0.76 repetitions (95% CI 0.64, 0.89 mean for knee from 10.0 to 14.3, and for hip from 10.9 to 14.8). …”

Casein kinase 1 inhibitor partly mimics <i>CSNK1G2</i> effect on PI3K/AKT/mTOR/S6K and ERK signaling in breast cancer cells. by Anh Thu Nguyen Hoang (10661003)

Summary of the treatment of 43 pediatric oncology patients with 44 episodes of mucormycosis, and those of episodes in which Mucorales infection was or was not considered to be the... by Gabriela A. Marón (17941257)

Leucophore formation does not require Sox10 function but is repressed by Sox10 and Sox5 (A-H) 9 dpf. by Yusuke Nagao (546940)

“…Leucophores (orange) are distributed along the dorsal surface throughout the anterioposterior axis of WT, as scattered individual cells in the head, and along the midline in the body (A). As the number of functional <i>sox10</i> alleles decreases, leucophore numbers on the head are progressively increased (A-D, I, <i>p</i><0.05 by Kruskal-Wallis test), whereas in the body they are progressively decreased (J, <i>p</i><0.05 by Kruskal-Wallis test). …”

Disrupting Glycolysis-promoting Genes Extends <i>C</i>. <i>elegans</i> Healthspan, Whereas High Glucose and Gluconeogenic Gene Disruptions Shorten Healthspan. by Brian Onken (86790)

“…Trials with 5 and 13 day old animals also showed impaired older age locomotion in 4% glucose (Supplemental <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008982#pgen.1008982.s002" target="_blank">S1A and S1B Fig</a>). …”

Effect of <i>CSNK1G2</i> on TAM-mediated PI3K/AKT/mTOR/S6K gene expression in human breast cancer cells. by Anh Thu Nguyen Hoang (10661003)

Image_5_Late-Onset OCD as a Potential Harbinger of Dementia With Lewy Bodies: A Report of Two Cases.jpeg by Solène Frileux (9043280)

Summary of all mass spectrometry data. by Tim Vellmer (12837414)

H₂O₂ reduces the infectivity of IAV. by Nobuo Okahashi (409721)

Time series of macrofaunal crustacean abundance at stations in DBO regions 2–5 over the 2010–2019 period. by Sue E. Moore (2932644)

Identification of amitriptyline HCl, flavin adenine dinucleotide, azacitidine and calcitriol as repurposing drugs for influenza A H5N1 virus-induced lung injury by Fengming Huang (8582019)

“…Using high-throughput RNA sequencing, we identified a total of 1,233 genes differentially expressed in A549 cells upon H5N1 virus infection. …”

Video_5_Intradermal Injection of Oxytocin Aggravates Chloroquine-Induced Itch Responses via Activating the Vasopressin-1a Receptor/Nitric Oxide Pathway in Mice.mp4 by Rulong Li (1891597)

“…Notably, conivaptan also directly decreased CQ-induced scratching. In conclusion, OT plays a role in CQ-induced scratching behavior via V1AR binding events. …”

Data_Sheet_1_A five domains assessment of sow welfare in a novel free farrowing system.zip by Kate Plush (19369684)

“…MR 127 ± 26.4 events, p = 0.019), and a decreased proportion of MR sows had facial injuries after farrowing (10% CI [5, 20] vs. 67% CI [47, 95], p < 0.001). …”

Data_Sheet_1_A five domains assessment of sow welfare in a novel free farrowing system.zip by Kate Plush (19369684)

“…MR 127 ± 26.4 events, p = 0.019), and a decreased proportion of MR sows had facial injuries after farrowing (10% CI [5, 20] vs. 67% CI [47, 95], p < 0.001). …”

Model verification of (A) water level and (B) depth averaged velocity under various discharges. by Haibin Xiong (11778010)

A list of small-molecule inhibitors reducing human PFK1 iso-enzyme activities. by Samo Lešnik (21073880)

(a) Neutral surfaces <i>v</i> = <i>v</i>(<i>k</i>, <i>p</i>) defined in Eq (12) with the parameter values <i>v</i> = 182.5 and <i>δ</i> = 0.45; (b) Typical neutral curve <i>v</i> =... by Xiaoli Wang (46677)

Effect of viable oral streptococci on the infectivity of IAV. by Nobuo Okahashi (409721)

Data_Sheet_1_Loud noise-exposure changes the firing frequency of subtypes of layer 5 pyramidal neurons and Martinotti cells in the mouse auditory cortex.docx by Ingrid Nogueira (15407156)

“…Specifically, type A PCs decreased initial firing frequency in response to +200 pA steps (p = 0.020) as well as decreased steady state firing frequency (p = 0.050) while type B PCs, on the contrary, significantly increased steady state firing frequency (p = 0.048) in response to a + 150 pA step 1 week after noise exposure. …”

The ORF7a protein of SARS-CoV-2 initiates autophagy and limits autophagosome-lysosome fusion via degradation of SNAP29 to promote virus replication by Peili Hou (4737219)

“…In this study, we demonstrate that overexpression of the SARS-CoV-2 ORF7a protein activates LC3-II and leads to the accumulation of autophagosomes in multiple cell lines, while knockdown of the viral <i>ORF7a</i> gene via shRNAs targeting <i>ORF7a</i> sgRNA during SARS-CoV-2 infection decreased autophagy levels. …”