Image5_Dipyridamole activates adenosine A2B receptor and AMPK/cAMP signaling and promotes myogenic differentiation of myoblastic C2C12 cells.tif by Miguel Marco-Bonilla (16970271)

“…We determined how the purinergic system modulates myogenesis using dipyridamole (blocks adenosine taken up by the cells) and tenofovir (inhibits ATP release) in a myoblast cell line.…”

Summary of the effect of maternal immune activation on serotonin and dopamine. by Pei-Tan Hsueh (752475)

“…We concluded that maternal immune activation induced by exposure to a low dose of LPS decreased cerebral 5-HT in parallel with the down-regulation of 5-HT-related genes (tph2 and slc6a4), resulting in anxiety-like behavior in the female offspring.…”

Boxplots showing the differences in miR-21-5p and miR-16-5p levels across increasing AKI severity based on Kidney Disease: Improving Global Outcomes (KDIGO) grades. by Tamar J. van der Aart (22184206)

The boxplots present the mean cross-validated integrated Brier scores from the 1000 simulations for each of the sample sizes for the interaction simulations. by Justine B. Nasejje (14307679)

AMPK Mediates Glucocorticoids Stress-Induced Downregulation of the Glucocorticoid Receptor in Cultured Rat Prefrontal Cortical Astrocytes by Shi-Ying Yuan (2937669)

“…Glucocorticoid-induced effects were attenuated by glucocorticoid-inducible kinase 1 (SGK1) inhibitor GSK650394, which also inhibited glucocorticoid induced phosphorylation of Forkhead box O3a (FOXO3a). Furthermore, glucocorticoid-induced down-regulation of GR was mimicked by the inhibition of AMPK and abolished by the AMPK activators or the histone deacetylase 5 (HDAC5) inhibitors. …”

Table_5_The RNA N6-Methyladenosine Methyltransferase METTL3 Promotes the Progression of Kidney Cancer via N6-Methyladenosine-Dependent Translational Enhancement of ABCD1.XLSX by Yue Shi (128342)

Video_2_Deficiency of TRIM32 Impairs Motor Function and Purkinje Cells in Mid-Aged Mice.AVI by Jian-Wei Zhu (285977)

“…In addition, deficiency of TRIM32 decreased Type I inositol 1,4,5-trisphosphate 5-phosphatase (INPP5A) levels in cerebellum. …”

Video_3_Deficiency of TRIM32 Impairs Motor Function and Purkinje Cells in Mid-Aged Mice.AVI by Jian-Wei Zhu (285977)

“…In addition, deficiency of TRIM32 decreased Type I inositol 1,4,5-trisphosphate 5-phosphatase (INPP5A) levels in cerebellum. …”

Image_2_Deficiency of TRIM32 Impairs Motor Function and Purkinje Cells in Mid-Aged Mice.TIF by Jian-Wei Zhu (285977)

“…In addition, deficiency of TRIM32 decreased Type I inositol 1,4,5-trisphosphate 5-phosphatase (INPP5A) levels in cerebellum. …”

Image_1_Deficiency of TRIM32 Impairs Motor Function and Purkinje Cells in Mid-Aged Mice.TIF by Jian-Wei Zhu (285977)

“…In addition, deficiency of TRIM32 decreased Type I inositol 1,4,5-trisphosphate 5-phosphatase (INPP5A) levels in cerebellum. …”

Video_1_Deficiency of TRIM32 Impairs Motor Function and Purkinje Cells in Mid-Aged Mice.AVI by Jian-Wei Zhu (285977)

“…In addition, deficiency of TRIM32 decreased Type I inositol 1,4,5-trisphosphate 5-phosphatase (INPP5A) levels in cerebellum. …”

Experiment 5. by Jiehui Qian (294581)

“…<p>a) Two lines and two bars flickered at 4 Hz during the 30-s adaptation phase; only flickering bars were shown during the afterimage phase. b) Left: the olive bar indicates the mean illusory decrease of the lower bar length in Experiment 5, 3.16%. …”

Image_2_MicroRNA-20a-5p Ameliorates Non-alcoholic Fatty Liver Disease via Inhibiting the Expression of CD36.tif by Xin Wang (91924)

“…However, under the condition of interference with CD36, further inhibition of miR-20a-5p would not cause lipid over-accumulation. In this study, we found that miR-20a-5p played a protective role in lipid metabolic disorders of NAFLD by targeting CD36, which indicated the prospect of miR-20a-5p as a biomarker and treatment target for NAFLD.…”

Image_1_MicroRNA-20a-5p Ameliorates Non-alcoholic Fatty Liver Disease via Inhibiting the Expression of CD36.TIF by Xin Wang (91924)

“…However, under the condition of interference with CD36, further inhibition of miR-20a-5p would not cause lipid over-accumulation. In this study, we found that miR-20a-5p played a protective role in lipid metabolic disorders of NAFLD by targeting CD36, which indicated the prospect of miR-20a-5p as a biomarker and treatment target for NAFLD.…”

Image_3_MicroRNA-20a-5p Ameliorates Non-alcoholic Fatty Liver Disease via Inhibiting the Expression of CD36.TIF by Xin Wang (91924)

“…However, under the condition of interference with CD36, further inhibition of miR-20a-5p would not cause lipid over-accumulation. In this study, we found that miR-20a-5p played a protective role in lipid metabolic disorders of NAFLD by targeting CD36, which indicated the prospect of miR-20a-5p as a biomarker and treatment target for NAFLD.…”

Reasons for Cognitive Aid Non-Use. by Anna Clebone (20805689)

“…</p><p>Results</p><p>The response rate was 64.5%. One-hundred eighty-five reasons for non-use were collected before the focused program and 149 after. …”

Reasons for Cognitive Aid Non-use by Event. by Anna Clebone (20805689)

“…</p><p>Results</p><p>The response rate was 64.5%. One-hundred eighty-five reasons for non-use were collected before the focused program and 149 after. …”

Taxonomy of Critical Events. by Anna Clebone (20805689)

“…</p><p>Results</p><p>The response rate was 64.5%. One-hundred eighty-five reasons for non-use were collected before the focused program and 149 after. …”

Early prenatal alcohol exposure alters imprinted gene expression in placenta and embryo in a mouse model by Heidi Marjonen (738402)

“…To clarify the molecular mechanisms of PAE we have used a mouse model of early alcohol exposure, which is based on maternal <i>ad libitum</i> ingestion of 10% (v/v) ethanol for the first eight days of gestation (GD 0.5–8.5). …”

Protons cause a greater increase in persistent sodium current in C373F/E1784K Na_V1.5. by Colin H. Peters (4430245)

“…The E1784K mutant increases the fraction of charge which recovers with the fast time constant of recovery and decreases the fraction of slow charge return. (<b>F <i>inset</i></b>) To measure the rate of gating current deactivation, we depolarized cells to 0mV (c) following a conditioning pulse to 0mV (a) and a recovery pulse of variable length to -150mV (b).…”