Showing 12,381 - 12,400 results of 101,259 for search '(( 5 step decrease ) OR ( 5 ((ng decrease) OR (((mean decrease) OR (a decrease)))) ))', query time: 1.55s Refine Results
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    Cell Substratum Adhesion during Early Development of <i>Dictyostelium discoideum</i> by Marco Tarantola (102609)

    Published 2014
    “…We used two independent assays to quantify cell-substrate adhesion in mutants and in wild-type cells as a function of development. Using a microfluidic device that generates a range of hydrodynamic shear stress, we found that substratum adhesion decreases at least 10 fold during the first 6 hr of development of wild type cells. …”
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    FOXO3a mediates the downregulation of GR induced by chronic exposure to GCs. by Shi-Ying Yuan (2937669)

    Published 2016
    “…<p>(A) Representative western blot images and summarized data showing the decreased expression of LKB1 (A) and the inhibitory phosphorylation of FOXO3a-Thr32 (B) in cultured astrocytes (n = 6 for each group). …”
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    Cyclization Decoded: Engineering Amylomaltase for Efficient α‑Glucan Transformations by Han Liu (288039)

    Published 2025
    “…Here, we harness large-scale computations in synergy with biochemical experiments to unravel, at atomic resolution, the full covalent and noncovalent catalytic mechanism of AMs, revealing that cyclization (12.8 kcal/mol) outcompetes hydrolysis (17.5 kcal/mol) as the dominant pathway. Furthermore, we identify that postglycosylation noncovalent polysaccharide chain transfer emerges as the decisive factor in cyclization, particularly for AM–degree of polymerization (DP) greater than 30 substrate complexes, where this noncovalent step (≥13.6 kcal/mol) dictates the rate of CA production. 57 variants with enhanced activity (up to a 2.3-fold increase) were engineered in our biochemical experiments by strategically modulating the chain transfer step. …”