Search alternatives:
step decrease » sizes decrease (Expand Search), teer decrease (Expand Search), we decrease (Expand Search)
ng decrease » nn decrease (Expand Search), _ decrease (Expand Search), we decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
5 step » _ step (Expand Search), a step (Expand Search), 2 step (Expand Search)
step decrease » sizes decrease (Expand Search), teer decrease (Expand Search), we decrease (Expand Search)
ng decrease » nn decrease (Expand Search), _ decrease (Expand Search), we decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
5 step » _ step (Expand Search), a step (Expand Search), 2 step (Expand Search)
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Cell Substratum Adhesion during Early Development of <i>Dictyostelium discoideum</i>
Published 2014“…We used two independent assays to quantify cell-substrate adhesion in mutants and in wild-type cells as a function of development. Using a microfluidic device that generates a range of hydrodynamic shear stress, we found that substratum adhesion decreases at least 10 fold during the first 6 hr of development of wild type cells. …”
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12388
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FOXO3a mediates the downregulation of GR induced by chronic exposure to GCs.
Published 2016“…<p>(A) Representative western blot images and summarized data showing the decreased expression of LKB1 (A) and the inhibitory phosphorylation of FOXO3a-Thr32 (B) in cultured astrocytes (n = 6 for each group). …”
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12399
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12400
Cyclization Decoded: Engineering Amylomaltase for Efficient α‑Glucan Transformations
Published 2025“…Here, we harness large-scale computations in synergy with biochemical experiments to unravel, at atomic resolution, the full covalent and noncovalent catalytic mechanism of AMs, revealing that cyclization (12.8 kcal/mol) outcompetes hydrolysis (17.5 kcal/mol) as the dominant pathway. Furthermore, we identify that postglycosylation noncovalent polysaccharide chain transfer emerges as the decisive factor in cyclization, particularly for AM–degree of polymerization (DP) greater than 30 substrate complexes, where this noncovalent step (≥13.6 kcal/mol) dictates the rate of CA production. 57 variants with enhanced activity (up to a 2.3-fold increase) were engineered in our biochemical experiments by strategically modulating the chain transfer step. …”