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14901
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14902
Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…In aged HSA-mUCP1 mice, urinary MG-derived AGEs/FL ratio was decreased ca. 60% whereas there was no change in CML/FL ratio – a marker of oxidative damage. …”
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14903
Breast Cancer 1 (BrCa1) May Be behind Decreased Lipogenesis in Adipose Tissue from Obese Subjects
Published 2012“…Consistent with its role limiting fatty acid biosynthesis, both <em>BrCa1</em> mRNA (3.5-fold, p<0.0001) and protein (1.2-fold, p = 0.001) were increased in pre-adipocytes, and decreased during <em>in vitro</em> adipogenesis, while P-ACC decreased during differentiation of human adipocytes (p = 0.005) allowing lipid biosynthesis. …”
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14904
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14905
A Role for <i>Smoothened</i> during Murine Lens and Cornea Development
Published 2014“…Mutant lenses were smaller and showed normal expression of p57Kip2, c-Maf, E-cadherin and Pax6, reduced expression of FoxE3 and Ptch1 and decreased nuclear Hes1. There was normal G1-S phase but decreased G2-M phase transition at E16.5 and epithelial cell death from E14.5-E16.5. …”
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14906
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14907
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14908
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14909
Spatiotemporal variability of soil nutrients and the responses of growth during growth stages of winter wheat in northern China
Published 2018“…The highest AN and AK contents were found at the reviving stage, while AP reached a turning point at the jointing stage. The order of variability of each nutrient was AN>AP>AK. 2) The nutrient variations first increased and then decreased and showed medium to strong spatial correlation. …”
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14910
Knockdown of UAP56 impairs A/chicken/Malaysia/5858/2004 H5N1 virus growth.
Published 2013“…Fourty-eight hours later, depleted cells were infected with A/chicken/Malaysia/5858/2004 H5N1 at MOI of 5. …”
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14911
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14912
Nonlatching positive feedback substantially dampens the Poissonian noise-mean inverse relationship, allowing stochastic extinction despite increasing mean-expression levels.
Published 2017“…<p>(A) In the classical Poisson or super-Poissonian transcriptional burst models [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.2000841#pbio.2000841.ref050" target="_blank">50</a>], the expression mean scales with variance (σ<sup>2</sup> ∝ μ) such that the noise magnitude (CV<sup>2</sup> = σ<sup>2</sup> / μ<sup>2</sup>) decreases proportionally to the inverse of the mean. …”
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14913
Synthesis, Structural Characterization, and DFT Investigations of [M<sub><i>x</i></sub>M′<sub>5–<i>x</i></sub>Fe<sub>4</sub>(CO)<sub>16</sub>]<sup>3–</sup> (M, M′ = Cu, Ag, Au; M ≠...
Published 2020“…Substitutional and compositional disorder is present in the solid state structures, and ESI-MS analyses point out that mixtures of isostructural clusters differing by a few M/M′ coinage metals are present. …”
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14914
Characterization of CFDP1-H2A.Z interaction.
Published 2024“…(E) CFDP1 depletion led to a remarkable reduction in chromatin incorporation of exogenously supplied FLAG-H2A.Z compared to control siRNA (con si)-treated cells (<2.5-fold). …”
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14915
Degradation of GKAP after Aβ treatment is mediated by cdk-5-dependent phosphorylation of two epitopes at S77 and S111.
Published 2011“…<p>(<i>A</i>) GKAP and cdk5 colocalize in synaptic sites. …”
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14916
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14917
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14918
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14919
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14920
DataSheet_4_RNA Demethylase ALKBH5 Prevents Lung Cancer Progression by Regulating EMT and Stemness via Regulating p53.zip
Published 2022“…Knockdown of ALKBH5 increased global m<sup>6</sup>A level, and also increased E-cadherin, decreased stem hallmarkers, Nanog and Oct4, and inhibited stemness of CSCs. …”