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step decrease » sizes decrease (Expand Search), teer decrease (Expand Search), we decrease (Expand Search)
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19841
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19842
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19843
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19844
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19845
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19846
Tumor Cells Switch to Mitochondrial Oxidative Phosphorylation under Radiation via mTOR-Mediated Hexokinase II Inhibition - A Warburg-Reversing Effect
Published 2015“…Three tumor cell lines (breast cancer MCF-7, colon cancer HCT116 and glioblastoma U87) showed a quick relocation of mTOR to mitochondria after irradiation with a single dose 5 Gy, which was companied with decreased lactate production, increased mitochondrial ATP generation and oxygen consumption. …”
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19847
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19848
Conformational characterization of a novel anti-HER2 candidate antibody
Published 2019“…In this work, the conformational features of a novel monoclonal antibody (called 5G4) were evaluated by means of circular dichroism spectroscopy and fluorescence. …”
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19849
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19850
<em>In Vitro</em> and <em>Ex Vivo</em> Analysis of <em>CHRNA3</em> and <em>CHRNA5</em> Haplotype Expression
Published 2011“…For <em>in vitro</em> analyses, promoter haplotypes were sub-cloned into a luciferase reporter vector. When assessed in BE(2)-C cells, luciferase expression was equivalent among <em>CHRNA3</em> haplotypes, but the combination of deletion at rs3841324 and variation at rs503464 decreased <em>CHRNA5</em> promoter-derived luciferase activity, possibly due to loss of an SP-1 and other site(s). …”
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19851
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19852
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19853
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19854
Effects of a clinical medication review focused on personal goals, quality of life, and health problems in older persons with polypharmacy: A randomised controlled trial (DREAMeR-s...
Published 2019“…Over 6 months, in the intervention group, HR-QoL measured with EQ-VAS increased by 3.4 points (95% confidence interval [CI] 0.94 to 5.8; <i>p</i> = 0.006), and the number of health problems with impact on daily life decreased by 12% (difference at 6 months −0.34; 95% CI −0.62 to −0.044; <i>p</i> = 0.024) as compared with the control group. …”
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19855
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19856
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19857
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19858
Changes in ELF5, FOXA1 and ER binding to the genome are reflected in gene expression.
Published 2020“…Panel <b>B</b>, as for panel A but showing genes for which FOXA1 or ER binding was increased or decreased by induction of ELF5. …”
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19859
ELF5 transcriptional effects measured by RNA-seq.
Published 2020“…<p>Panel <b>A</b>, GO ontologies enriched in the RNA-seq data set by induction of ELF5, font size relative to enrichment score. …”
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19860
The MITF-SOX10 regulated long non-coding RNA DIRC3 is a melanoma tumour suppressor
Published 2019“…<i>DIRC3</i> is a nuclear lncRNA that activates expression of its neighbouring <i>IGFBP5</i> tumour suppressor through modulating chromatin structure and suppressing SOX10 binding to putative regulatory elements within the <i>DIRC3</i> locus. …”