Low concentrations of siRNA TMPRSS2-ERG III and IV impair TMPRSS2-ERG oncogene and oncoprotein levels but not cell viability. by Giorgia Urbinati (554921)

“…<p>VCaP cells were transfected for 72h from 2.5 nM to 50 nM with siRNA TMPRSS2-ERG III, siRNA TMPRSS2-ERG IV or siRNA Control. …”

ECE treatment decreases coronavirus production in the cells. by Siyun Lee (17087351)

“…<p><b>(A)</b> ECE treatment decreased the coronavirus protein in the infected cells. …”

MnTBAP treatment reduces caloric intake in mice fed a HFD. by Jonathan R. Brestoff (799142)

Comparison of cerebral infarct volume between the CCH and control groups. by Jung-In Lee (1731727)

Representative examples of iNOS (1^st row), RANK (2^nd row) and TRAP (3^rd row) immunostainning in experimental periodontitis in rats. by Conceição S. Martins (468492)

Influence of ghrelin treatment (0.5 μg/g BW, twice a day, intraperitoneal (ip.)) on oxidative burst capacity of neutrophils after cecal ligation and puncture (CLP)-induced sepsis. by Daniel Siegl (717509)

Influence of ghrelin treatment (0.5 μg/g BW, twice a day, intraperitoneal (ip.)) on peritoneal cellular immune response after cecal ligation and puncture (CLP)-induced sepsis. by Daniel Siegl (717509)

Kcnk5b activity induces IP₃R-mediated Ca²⁺ release from the ER. by Xiaowen Jiang (8291814)

Normal cell death but decreased cell proliferation of in <i>MiR125a</i>^-/- neutrophils. by Yuting Qin (1950118)

Decreased proliferation of immature neutrophils in <i>MiR125a</i>^<i>-/-</i> mice. by Yuting Qin (1950118)

Coibamide A induces a time- and concentration-dependent decrease in plasma membrane integrity. by Andrew M. Hau (418935)

Individual relationship between muscle lactate concentrations and PCr concentrations (expressed in percent of initial value) (2A) and between PCr decreases (expressed in percent of initial value) and muscle IMP concentrations (2B), during 10REP (open circles), and 5REP (filled circles). by Esteban M. Gorostiaga (316019)

“…<p>Individual relationship between muscle lactate concentrations and PCr concentrations (expressed in percent of initial value) (2A) and between PCr decreases (expressed in percent of initial value) and muscle IMP concentrations (2B), during 10REP (open circles), and 5REP (filled circles).…”

Summary of the A19D unfolding pathway highlighting the main structural changes identified here that might explain its decreased thermodynamic stability. by Priscila Ferreira (498747)

LiCl administered via 0.5% LiCl food pellets for 4 wks does not increase markers for autophagy in <i>Gfap-</i>R236H/+ mice. by Christine M. LaPash Daniels (796881)

Cullin-1/5 degradation requires Gal-lectin-mediated contact with macrophage. by Attinder Chadha (11414273)

Subjects:

Antineoplastic Effects of siRNA against TMPRSS2-ERG Junction Oncogene in Prostate Cancer by Giorgia Urbinati (554921)

“…The siRNA against TMPRSS2-ERG fusion variant IV showed the highest anti-proliferative effects: Significantly decreased cell viability, increased cleaved caspase-3 and inhibited a cluster of anti-apoptotic proteins. …”

TGFβ1 expression was increased, and RASAL1 expression was decreased in NTM cells in response to a hypoxic environment. by Fiona McDonnell (2636635)

“…A 0hr Control was set to 100%, and the normoxic and hypoxic results were presented as a percentage of this; Normoxic = 95.5%, Hypoxic = 159.4% (P<0.01). n = 3 *P<0.05, **P<0.01. …”

LiCl administered via 0.5% LiCl food pellets for 8 wks decreases GFAP levels in surviving <i>Gfap</i>-R236H/+ mice. by Christine M. LaPash Daniels (796881)

“…<p>(A) 81.8% (9/11) +/+ mice and 54.5% (6/11) R236H/+ mice survived 8 wks of LiCl treatment. …”

Knockdown of p65 in A549 cells results in a decreased infection rate. by Janine J. Wilden (8849948)

Knockdown of OPTN decreases starvation induced formation and maturation of autophagosomes. by Kapil Sirohi (796637)