Image5_Analysis of Brain Lipids in the Early-Onset Tay–Sachs Disease Mouse Model With the Combined Deficiency of β-Hexosaminidase A and Neuraminidase 3.jpg by Melike Can (13210755)

“…</p><p>Histochemical studies showed a decrease in the myelin level and axonal degeneration indicating neuronal pathology in the brain of Hexa−/−Neu3−/− mice. …”

The HMR C-terminus is required for HMR localization in proximity to centromeres and HP1a-bound chromatin (related to Fig 4). by Andrea Lukacs (3752956)

The influence of H₂O₂ on <i>P</i>. <i>berghei</i> infection in <i>A</i>. <i>stephensi</i>. by Li Gao (131516)

Change in fluorescein staining scores and tear breakup time (TBUT) at follow-up after rebamipide instillation treatment in SS-DE patients. by Jun Shoji (724385)

In individuals affected by PCA, there is a significant downregulation of genes associated with the cholesterol biosynthetic pathway. by Leemon Nikhila (22250736)

Table_5_Identification and Confirmation of the miR-30 Family as a Potential Central Player in Tobacco-Related Head and Neck Squamous Cell Carcinoma.xlsx by Tingting Zhang (264633)

“…Moreover, we uncovered that KRAS might be the potential target gene of miR-30e-5p or miR-30b-5p. Thus, our data clearly showed that decreased expression of miR-30e-5p or miR-30b-5p may play a crucial role in cancer development, especially that of tobacco-induced HNSCC, and may be a novel candidate biomarker and target for this HNSCC subtype.…”

Decrease of C/EBPβ protein expression attenuates DEX-induced repression of CBG mRNA and protein levels and reduces GR recruitment to the mouse <i>Cbg</i> promoter. by Nicolette Verhoog (647814)

“…Occupancy of GR protein on the endogenous mouse <i>Cbg</i> promoter was detected using primers encompassing the regions defined as P5 to P1. Co-immunoprecipitated DNA fragments and input DNA were analyzed by qPCR and results shown are normalized to a non-specific region within the m<i>Cbg</i> promoter as well as input and expressed relative to NSC vehicle control (0.1% EtOH), which was set as 1. …”

Data_Sheet_1_Manipulation of an α-glucosidase in the industrial glucoamylase-producing Aspergillus niger strain O1 to decrease non-fermentable sugars production and increase glucoa... by Wenzhu Guo (501328)

“…The results showed the transglycosylation product panose was decreased by more than 88.0% in agdA/agdB double knock-out strains than strain O1. …”

Cross-network FC among RSNs for CN group (A), FBSS group (B), and difference (C), respectively. by Peter A. Pahapill (8468607)

Effect of expressing ^H2F1 WT or Znf5 C2>A2 on the REH2 steady-state abundance. by Vikas Kumar (153353)

“…<p><b>(A)</b> Western blots of extracts with tagged ^H2F1 WT (lanes 1–2) or Z5 C2>A2 (Z5; lanes 3–4). …”

Andexanet alfa effectively reverses edoxaban anticoagulation effects and associated bleeding in a rabbit acute hemorrhage model by Genmin Lu (5029949)

“…</p><p>Materials and methods</p><p><i>In vitro</i> studies characterized the interaction of andexanet with edoxaban and its ability to reverse edoxaban-mediated anti-FXa activity. In a rabbit model of surgically induced, acute hemorrhage, animals received edoxaban vehicle+andexanet vehicle (control), edoxaban (1 mg/kg)+andexanet vehicle, edoxaban+andexanet (75 mg, 5-minute infusion, 20 minutes after edoxaban), or edoxaban vehicle+andexanet prior to injury.…”

The time course of the fraction of intact DOPG/DOPC (40/60)-GUVs and the rate constant of rupture and electrofusion at different frequencies of DC pulses under <i>σ</i>_e... by Md. Tariqul Islam Bhuiyan (18794375)

The Catalytic Subunit of the System L1 Amino Acid Transporter (<i>Slc7a5</i>) Facilitates Nutrient Signalling in Mouse Skeletal Muscle by Nadège Poncet (527942)

“…These changes were associated with >50% decrease in S6K Thr389 phosphorylation in muscles from MS-<i>Slc7a5</i>-KO mice, indicating reduced mTOR-S6K pathway activation, despite no significant differences in lean tissue mass between groups on the same diet. …”

Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial by Sergio Serrano-Villar (517286)

“…In the duodenum, the quadruple regimen resulted in greater CD8⁺ T-cell density decline, greater normalization of mucosal CCR5⁺CD4⁺ T-cells and increase of the naïve/memory CD8⁺ T-cell ratio, and a greater decline of sCD14 levels and duodenal HIV DNA levels (P = 0.004 and P = 0.067, respectively), with no changes in HIV RNA in plasma or tissue. …”

LncRNA GAS5 knocked-down THP-1 cells treated with 75 μg/mL oxLDL reduced cell apoptosis. by Lei Chen (54296)

“…<p><b>A</b>. RT-PCR analysis of lncRNA GAS5 expression in NC and lncRNA GAS knocked-down cells. …”

Image_5_Preservation of exopolymeric substances in estuarine sediments.JPEG by Thibault Duteil (13264521)

“…EPS results were analyzed in the context of sediment properties including facies, grain size, and total organic carbon, and of metabolic and enzymatic activities. Our results showed a predictable decrease in EPS concentrations (proteins and polysaccharides) and reactivity from the surface biofilm to a depth of 0.5 m, possibly linked to heterotrophic degradation. …”

Representative images of EC cortical actin cytoskeleton at different growing states visualized by Phalloidin staining and confocal microscopy. by Leike Xie (1317108)

Chain Conformation, Molecular Dynamics, and Thermal Properties of Poly(<i>n</i>‑methylene 2,5-furanoates) as a Function of Methylene Unit Sequence Length by George Papamokos (1595743)

“…Poly­(<i>n</i>-methylene 2,5-furanoates) is a family of biobased polymers with outstanding gas barrier and mechanical properties and with the potential to frame the future in certain applications (e.g., food packaging, fibers, and engineering thermoplastics). …”

Scheme of the test section. by Decang Lou (21439960)

“…The results reveal that the large deviation in the manufactured vane (up to 0.5 mm at the leading edge) alters the direction of the coolant flowing out from the leading-edge film-cooling holes, affects the film coverage along the surface, and in consequence, causes the temperature near the stagnation point increasing by approximately 40 K. …”

Effects on cooling air mass flow rate. by Decang Lou (21439960)

“…The results reveal that the large deviation in the manufactured vane (up to 0.5 mm at the leading edge) alters the direction of the coolant flowing out from the leading-edge film-cooling holes, affects the film coverage along the surface, and in consequence, causes the temperature near the stagnation point increasing by approximately 40 K. …”