Treatment of ARDS tracheal aspirates with MMP-8 and MMP-9 inhibitors. by Michele Y. F. Kong (346852)

“…Tracheal aspirates from ARDS subjects (n = 4) with high MMP-9 activity were examined in the presence of different MMP inhibitors. MMP-9 activity decreased by 70–100% relative to basal activity in the presence of EDTA (5 mM; ^†<i>p = 0.008</i>) and a MMP-9 specific inhibitor (50 ng/ml; ^‡<i>p = 0.008</i>). …”

Zic3 binds specifically to its canonical motif. by Cecilia L. Winata (226096)

“…A positive shift is indicated by a decrease in mobility (red arrowheads).…”

LET-60 (Ras) activation is sufficient to cause tail swelling and is required for the Dar response to infection. by Rachel McMullan (183027)

“…Cell specific expression of constitutively active MEK- 2(S223E, S227D) (<i>egl-5p</i>::MEK-2*) (D) or constitutively active LET-60(G12V) (<i>egl- 5p</i>::LET-60*) (E) in the rectal epithelial cells using a 1.3 Kb <i>egl-5</i> promoter fragment resulted in tail swelling that phenocopied the Dar phenotype observed following infection and RHO-1* activation. …”

GAP and PPI ratios for the tinnitus⁽⁺⁾, tinnitus⁽⁻⁾ and control groups. by Edward Pace (457986)

“…<p>Gap-detection data showed tinnitus across all frequency bands and BBN at 1 to 2 and 5 to 6 weeks post-exposure in the tinnitus⁽⁺⁾ group (A). …”

Reduced epidermal proliferation and differentiation in skin wounds from Ctip2^ep−/− mice. by Xiaobo Liang (183523)

“…<p>(<b>A–C</b>) Expression of PCNA in skin sections from Ctip2^L2/L2 and Ctip2^ep−/− mice on day 5 (A and B) and day 7(C) post wounding, using antibodies against PCNA (in red). …”

Prebiotic diet containing scGOS/lcFOS significantly alters the composition of intestinal microbiota of IL-1Ra^-/- mice. by Rebecca Rogier (4171054)

“…<p>Phylogenetic tree created by Cytoscape software showing specific changes in intestinal microbial community at different taxonomic levels in the mice fed 2.5% scGOS/lcFOS diet compared to mice fed a control diet. …”

Effect of herb-drug interactions of Bacopa monnieri Linn. (Brahmi) formulation on the pharmacokinetics of amitriptyline in rats by Fowad Khurshid (12039023)

“…Pretreatment with B. monnieri produced a significant increase in the maximum plasma concentration (Cmax), area under the curve (AUC0-t) and elimination half-life (t1/2) of amitriptyline by 16.8%, 26.5%, and 15.5%, respectively, compared to amitriptyline alone. …”

Evolution of Microscopic Groups in Coal Under Air Leakage Disturbance and in-Situ Temperature Increase by Jiangkun Chao (14421438)

“…The content of aliphatic hydrocarbons follows a pattern of initial increase followed by a subsequent decrease. …”

RanGAP1 RNA interference increased tumor cell death and cell-cycle arrest but had no effect on non-neoplastic LCL cells. by Kung-Chao Chang (170593)

“…<p>(<b>A</b>) After transfection, the effect of inhibiting RanGAP1 was evaluated in the LCL (upper panel), HT (middle panel), and SU-DHL-5 cell lines (lower panel) for cell death, measured using annexin V and PI (propidium iodide). …”

Table_1_Investigating the Use of Dry Matter Intake and Energy Balance Prepartum as Predictors of Digestive Disorders Postpartum.DOCX by Johanny Pérez-Báez (11439520)

“…<p>One objective was to evaluate the association of dry matter intake as a percentage of body weight (DMI%BW) and energy balance (EB) prepartum and postpartum, and energy-corrected milk (ECM) postpatum with digestive disorders postpartum. …”

DataSheet1_Changes in Organic Matter Deposition Can Impact Benthic Marine Meiofauna in Karst Subterranean Estuaries.xlsx by David Brankovits (10793055)

“…These patterns suggest that a reduction in the local mangrove habitat decreased the terrestrial particulate OM input to the cave over time. …”

In vitro studies on effect of Cisplatin and paclitaxel on PIK3CA promoter and p53. by Snehal M. Gaikwad (279479)

“…A dose dependent decrease in luciferase activity (<i>PIK3CA</i> promoter activity) was observed on increasing concentrations of cisplatin treatments in PPF cells (at 3 & 5 µg/ml cisplatin, p<0.03) (2a) and in APFT cells at 20 and 30 µg/ml cisplatin (p<0.003) (2c). …”

DataSheet2_Changes in Organic Matter Deposition Can Impact Benthic Marine Meiofauna in Karst Subterranean Estuaries.pdf by David Brankovits (10793055)

“…These patterns suggest that a reduction in the local mangrove habitat decreased the terrestrial particulate OM input to the cave over time. …”

Image_1_Tumor Suppressive Maspin-Sensitized Prostate Cancer to Drug Treatment Through Negative Regulating Androgen Receptor Expression.TIF by Sijie Tang (8494560)

“…In the current study, treatment of 5′-Aza or MS-275/enzalutamide induced poly (ADP-ribose) polymerase (PARP) cleavage and p-H2A.X in CaP cells with an increase of maspin expression but a decrease of AR. …”

Image_2_Tumor Suppressive Maspin-Sensitized Prostate Cancer to Drug Treatment Through Negative Regulating Androgen Receptor Expression.TIF by Sijie Tang (8494560)

“…In the current study, treatment of 5′-Aza or MS-275/enzalutamide induced poly (ADP-ribose) polymerase (PARP) cleavage and p-H2A.X in CaP cells with an increase of maspin expression but a decrease of AR. …”

Intestinal enteroids recapitulate the effects of short-chain fatty acids on the intestinal epithelium by Sarah C. Pearce (8661816)

“…Gene expression of <i>Lgr5</i> was shown to decrease with BUT and PROP treatments, but increased with ACET. …”

Knockdown of α-actinin-2 increases spine number and inhibits spine maturation. by Jennifer L. Hodges (207936)

“…Overexpression of α-actinin-2-SS increases spine length (F) and reduces spine head width (G). α-Actinin-2-SS overexpression creates an increase in the fraction of filopodia-like spines and a decrease in the fraction of stubby spines, H. …”

Gene function in early mouse embryonic stem cell differentiation-4 by Kagnew Hailesellasse Sene (25572)

Effect of polymer composition. by Yi Bao (278186)

“…Data are presented as mean ± SEM; N > 3. We examined the effect of polymer composition on NPs using acetonitrile to dissolve different mass ratios of PLGA(M) with PEG-PLGA at 5 mg/mL concentration, TFR = 300 μL/min, and FRR = 5. …”

Phase I mRNA components are significantly reduced in several newborn tissues in the absence of pRb. by Maria Teresa Sáenz Robles (201330)

“…Adh levels are used as endogenous controls. b) RNAs from newborn tissue samples were analyzed by Real time PCR, indicating that Cyp3A11 and Cyp3a25 mRNAs decrease substantially in samples lacking a functional RB gene in all tissues tested: liver; small intestine and lungs. …”