Cdk5 activity is required for Aβ-induced GKAP down-regulation. by Francesco Roselli (211670)

“…Rat frontal neurons were transfected with GKAP-GFP-WT together with either β-Galactosidase (β-Gal, negative control) or PSD-95-WT or PSD-95-AAA at DIV5–6 and treated with Aβ (1 µM, 1 h) at DiV9. Overexpression of PSD-95 WT and PSD-AAA alone caused the increase in GKAP-GFP cluster size (158.2±12.3% and 202.4±32.5% of GKAP-GFP/βGal, respectively); Aβ treatment determines a significant decrease in GKAP-GFP cluster size (75.6±5.7% PSD-95WT/GKAP-GFP+Aβ vs PSD-95WT/GKAP-GFP alone; 66.8±9.9% PSD-95-AAA/GKAP-GFP+Aβ vs PSD-95-AAA/GKAP-GFP alone, all p<0.05). …”

Technological time lag (fpcy) for SB-SNPRs with <i>s</i> = 5 from 1990: corrected (blue triangles) and not-corrected (red diamonds) for inventor-author patent citations. by Anthony F. J. van Raan (7517696)

Fig 1 - by Domenico Maurizio Toraldo (9071920)

Hepatic secretion of lipid and apoB with MTP knockdown. by Stephanie M. Marshall (223125)

Pharmacological targeting of polyamine and hypusine biosynthesis reduces tumour activity of endometrial cancer by Hong Im Kim (4686187)

“…We show that eIF5A1 is significantly upregulated in EC cells compared to control cells (<i>p</i>=.000038) and that combined pharmacological targeting of ODC and eIF5A hypusination with cytostatic drugs DFMO and N1-guanyl-1,7-diaminoheptane (GC7), respectively, reduces eIF5A1 activation and synergistically induces apoptosis in EC cells. …”

Evidence of High Out of Pocket Spending for HIV Care Leading to Catastrophic Expenditure for Affected Patients in Lao People's Democratic Republic by Hubert Barennes (333382)

“…</p><p>Methods</p><p>We conducted a cross-sectional survey of a randomized sample of routine outpatients and a prospective survey of consecutive new inpatients at two referral hospitals (Setthathirat in the capital city, Savannaket in the province). …”

iNOS-KO rats show slow clearance of <i>S</i>. <i>japonicum</i>, exacerbated pathological responses and increased morbidity. by Jia Shen (1828945)

Linear mixed effects modeling parameter estimates of IgG antibodies to SARS-CoV-2 spike (full length spike, S) and neutralizing antibodies in nursing home residents—Georgia, Decemb... by Zeshan A. Chisty (18388200)

Fig 2 - by Calvin P. Philp (12095878)

gcn5-F221A can impart a graded phenotype as detected by histidine starvation assays. by Amanda M. Lanza (168454)

“…Increasing the expression level of <i>gcn5-F221A</i> (through progressively stronger promoters) results in a decrease in growth rate approaching the value of the knockout strain. …”

Primary monocytes at 1 x 10⁶ cells were seeded in a flask and supplemented with RPMI 1640 + GM-CSF + IL-4 and incubated at 37°C for 6 days for monocyte to macrophage tra... by Janani Madhuravasal Krishnan (19736002)

Brain acylcarnitines. by Dawn B. Lammert (21175128)

Effect of NAIs exposure on rat skin TGFβ1 and VEGFR-2 expression in the wound healing of four groups of rats. by Yu-Hsuan Cheng (4840704)

Time constants of approximating exponents as functions of stimulus level, keeping the relative level of the previous stimulus as a parameter; <i>s</i> (silence)–no previous stimulu... by Vladimir V. Popov (5563067)

Trade-off between phenotypic variation (<i>V</i>_<i>ip</i>) and fitness. by Naoto Nishiura (11668953)

Details the amount of fertilizer applied to blueberries over a 10-day period during each stage (Compounds). by Xianyong Wang (22601067)

FASN was not altered in fasting in mice with reduced myocardial PPARα. by Natasha Fillmore (322163)

Effects of TNF-α on the cochlear hair cells in middle-turn cochlear explants. by Byung Chul Kang (1905025)

Altered selection of branch sites by <i>sf3b1</i> mutants. by Bei Zhang (428038)

SIRT3 affected mitochondrial function in AngII-induced cardiomyocytes. by Ling-Xin Liu (18387955)