Identification of small molecules that inhibit viral M mRNA nuclear export and/or decrease viral M mRNA levels. by Matthew Esparza (8661219)

“…<p>(<b>A</b>) Representative images showing uninfected cells; cells infected with A/WSN/33 and pretreated with 0.5% DMSO (control), which show viral M mRNA exported into the cytoplasm, in red; and cells infected with A/WSN/33 pre-treated with 2.5 μM of the transcription inhibitor DRB (5,6-dichloro-1-β-D-ribofuranosylbenzimidazole). …”

Frontier molecular orbitals (FMOs; optimized, HOMO, LUMO) pictures of two neighboring quaternary ammonium-based rings without (5) and with one (6a) or two (6b) alkyl chains and no... by Ghadeer Mubarak (21567569)

Figure 4 from Claudin-4 Modulates Autophagy via SLC1A5/LAT1 as a Mechanism to Regulate Micronuclei by Fabian R. Villagomez (18098633)

Audio_5_Changes in humpback whale song structure and complexity reveal a rapid evolution on a feeding ground in Northern Norway.wav by Saskia C. Tyarks (14239100)

DataSheet_1_Pharmacological activation of the C5a receptor leads to stimulation of the β-adrenergic receptor and alleviates cognitive impairment in a murine model of familial Alzhe... by Eleni Fella (3925409)

“…We have previously administered the modified C5a receptor agonist (EP67) for a short period to a transgenic mouse model of AD (5XFAD) and have observed not only reduction in β-amyloid deposition and gliosis but also improvement in cognitive impairment. …”

Plasma TNFRSF11B as a New Predictive Inflammatory Marker of Sepsis–ARDS with Endothelial Dysfunction by Dong Zhang (73558)

“…Western blot results demonstrated that the levels of syndecan–1, claudin–5, VE–cadherin, occludin, aquaporin–1, and caveolin–1 in TNFRSF11B-stimulated HUVECs decreased, whereas that of connexin-43 increased in TNFRSF11B-stimulated HUVECs. …”

Therapeutic administration of mMSCs failed to decrease pulmonary inflammation or modify BAL inflammatory cell counts in experimental severe influenza. by Ilyse Darwish (446378)

<i>In-vitro</i> reduced albumin from HD patients decrease the mRNA expression of inflammatory cytokines and adhesion molecules. by Faiga Magzal (4045067)

IL-13-induced decrease of DKK-1 mRNA expression is reversed by an anti-IL-13 antibody in IEC and in fibroblasts. by Sandra Michaela Frei (481531)

Average running wheel activity in the light phase (A) and the dark phase (B) during three experimental sessions: Acclimatization (days 1 to 10), acute FR (days 11 to 17), and chron... by Toru Kuriyama (16631992)

Microgel assembly / dispersion are temperature dependent. by Chi-Shuo Chen (234719)

Competitive Arsenate and Phosphate Adsorption on Ferrihydrite as Described by the CD-MUSIC Model by Jon Petter Gustafsson (1851535)

“…This causes a flatter adsorption isotherm for As­(V), which leads to a stronger As­(V) adsorption as the As­(V)-to-Fe ratio decreases, compared to that for PO₄.…”

Upregulation of Cx30 impairs pyramidal cell excitability and action potential properties. by Eléonore Hardy (15208385)

Overexpression of G6PD rescued the high glucose-indueed decrease in the antioxidant enzymes and reduced ROS level in endothelial cells. by Zhaoyun Zhang (118032)

“…Endothelial cells were infected with either Ad2-G6PD (MOI: 5) or empty vector control (Laz). A: G6PD protein was significantly increased with adenovirus infection in endothelial cells exposed to high glucose. …”

Decrease in gastrin-, histidine decarboxylase-, and somatostatin mRNA due to the <i>H. pylori</i> B128 WT-infection. by Tobias Wiedemann (266622)

Discovery of Oral AMP-Activated Protein Kinase Activators for Treating Hyperlipidemia by Mingchao Wang (450503)

“…A single dose of V1 (2000 mg) increased AMPK activation in human erythrocytes after 5 and 12 h of treatment. …”

PON2 gene expression exhibits similar trends to the PON2 protein concentration levels measured using Western blot, with a trend towards decreased PON expression in asthma-obese (n = 5, 11.6 ± 0.22; mean ± standard error in VST-normalized messenger RNA levels) compared to lean participants (n = 4, 11.9 ± 0.062). by Daniel Efrain Winnica (12239641)

Gu-4 improves survival in septic rats and this improvement is accompanied by marked decrease of HMGB1 and TNF-α level in serum. by HuiTing Zhou (333755)

<i>Aspergillus flavus</i> mRNA expression (a) <i>aflD</i> and (c) <i>aflR</i> and phylogenetic analysis of (b) <i>aflD</i> and (d) <i>aflR</i> after exposure to 50 mg/mL of <i>U. e... by Martha Cebile Jobe (21175426)

Filaggrin silencing by shRNA directly impairs the skin barrier function of normal human epidermal keratinocytes and then induces an immune response by N.N. Dang (6513023)

“…Filaggrin silencing also resulted in significant increases of IL-2, IL-4, IL-5, and IL-13 (P<0.05 or P<0.01), and significant decreases of IL-12p70 and IFN-γ (P<0.01) compared with cells in the Blank and NC groups. …”