Data_Sheet_2_A Comparative Analysis of Reactive Müller Glia Gene Expression After Light Damage and microRNA-Depleted Müller Glia—Focus on microRNAs.pdf by Seoyoung Kang (10033280)

“…We found: (1) The vast majority of MG miRNAs declined in reactive MG 7 days after light damage. (2) Only four miRNAs increased after light damage, which included miR-124. (3) The top 10 genes found upregulated in reactive MG after light damage include Gfap, Serpina3n, Ednrb and Cxcl10. (4) The miRNA decrease in reactive MG 7 days after injury resembles the profile of Dicer-depleted MG after one month. (5) The comparison of both mRNA expression datasets (light damage and Dicer-cKO) showed 1,502 genes were expressed under both conditions, with Maff , Egr2, Gadd45b, and Atf3 as top upregulated candidates. (6) The DIANA-TarBase v.8 miRNA:RNA interaction tool showed that three miRNAs were found to be present in all networks, i.e., after light damage, and in the combined data set; these were miR-125b-5p, let-7b and let-7c. …”

Anteriorly traveling Lfng stripes and segmentation-clock period. by Susan D. Hester (204004)

“…We increase or decrease the segmentation-clock period by varying how long we integrate the segmentation-clock ODEs during each time step; by doing so, we easily vary the clock period relative to other processes in the simulation without altering parameters within the segmentation-clock submodel or changing the clock response to FGF8, Wnt3a or Delta/Notch signaling. …”

Over-expression and inhibition of miR-221 and miR-222 result in modulation of p27. by Beatrice Cardinali (120407)

Optimisation of read depth, DNA quantity, and unique alternate observation threshold. by Melinda L. Tursky (20790436)

“…Almost all variants at ≥ 0.02 VAF were detected using an input DNA of ≥ 50ng, however detection of variants at < 0.02 VAF benefitted from increasing input DNA amounts. …”

Synthesis and properties of fluorinated copolymerized polyimide films by Chuanhao Cao (10396166)

“…With the increase of 6FDA in the proportion of dianhydride, the tensile strength of the polyimide film showed a decreasing trend. This work provided a high performance film. …”

Blocking interaction between phospho-cofilin and PLD1 prevents gLTP-induced spine head enlargement. by Barbara Calabrese (553229)

EARP, not GARP, is important for locomotion and trafficking dense-core vesicle cargos. by Irini Topalidou (2794261)

“…(D) IDA-1::GFP (<i>ceIs72</i> transgene) fluorescence levels in the dorsal cord. The <i>vps-50(ok2627)</i> deletion mutant had decreased IDA-1::GFP fluorescence (**, P<0.01) but the <i>vps-50(n4022)</i> late stop mutant and a <i>vps-54(ok1463)</i> deletion mutant had no decrease. …”

Open-Shell Lanthanide(II+) or -(III+) Complexes Bearing σ‑Silyl and Silylene Ligands: Synthesis, Structure, and Bonding Analysis by Rainer Zitz (1355943)

Knockdown of leptin receptor in pancreatic cancer cells leads to functional impairment of leptin signaling. by Alisha M. Mendonsa (456343)

“…<p>Long and short leptin receptor RNA levels measured through realtime PCR analysis were both significantly decreased using two different shRNAmir lentiviral titers in the Panc02 cell line (A). …”

Anthocyanin-rich compounds extracted from bilberry and blackcurrants inhibit <i>in vitro</i> osteoclastogenesis, but not osteogenesis. by Sawako Moriwaki (563407)

“…B: Anti-osteoclastogenic activity of anthocyanin compound was evaluated by the absorption ratio of the red-stained area per well at 520 nm on a spectrometer. C: Primary osteoblastic cells were cultured in the medium containing 50 µg AA, 10 µM Dex and 10 mM β-GP with or without anthocyanin compound for 2 weeks. …”

Table2_A Mendelian randomization study for drug repurposing reveals bezafibrate and fenofibric acid as potential osteoporosis treatments.docx by Xiao-Hua Li (1508020)

“…The genetically decreased LDL-C level mediated by the PPARG was significantly associated with increased FN-BMD (BETA = −1.38, p = 0.001) and LS-BMD (BETA = −2.07, p = 3.35 × 10⁻⁵) and was marginally significantly associated with FA-BMD (BETA = −2.36, p = 0.008) and reduced fracture risk (OR = 3.47, p = 0.008). …”

Table1_A Mendelian randomization study for drug repurposing reveals bezafibrate and fenofibric acid as potential osteoporosis treatments.docx by Xiao-Hua Li (1508020)

“…The genetically decreased LDL-C level mediated by the PPARG was significantly associated with increased FN-BMD (BETA = −1.38, p = 0.001) and LS-BMD (BETA = −2.07, p = 3.35 × 10⁻⁵) and was marginally significantly associated with FA-BMD (BETA = −2.36, p = 0.008) and reduced fracture risk (OR = 3.47, p = 0.008). …”

Clinical and virological profiles of EVN_Term challenged vaccinated and naïve ponies. by Jodi K. Craigo (421284)

“…<p>The profiles depicted in A–I display the clinical and virological outcomes observed in EIAV_D9 vaccinated animals (<b>A–E</b>), and EIAV naïve animals (<b>F–I</b>) upon challenge with 10³ TCID₅₀ EV_NTerm chimeric proviral strain. …”

Inhibition of full-length wild-type capsid polymerization kinetics by two CA binding agents. by Magdeleine Hung (158371)

“…The dose response curves of inhibition of polymerization kinetics and the concentration of inhibitor resulting in a half-maximal inhibition (IC₅₀) for (<b>B</b>) CAI-4 and (<b>D</b>) BM2. …”

Bortezomib inhibits infectious DENV production in primary monocytes. by Milly M. Choy (790882)

“…(E) Bortezomib also inhibited 50% of virus production of the attenuated strain of yellow fever virus, YF17D, at a concentration of 0.5 nM. …”

The effect of sonication and heat treatment on the physicochemical, nutritional and microbiological properties of different sugarcane variants by Nazariah JASMI (8183856)

The K_V10.1 life cycle includes recycling of internalized channels to the plasma membrane. by Tobias Kohl (254238)

Model of the relationship between lifespan and DR protocols that reduce access to food either by intermittent exposure (left panel) or nutrient dilution (right panel). by Richard C. Grandison (375194)

DataSheet_1_Patient-Reported Outcomes-Guided Adaptive Radiation Therapy for Head and Neck Cancer.docx by Sarah Weppler (10931013)

“…Dose-PRO relationships were strongest between delivered pharyngeal constrictor Dmean and patient-reported dysphagia, with MDADI composite scores (mean ± SD) of 25.7 ± 18.9 for patients with Dmean <50 Gy vs. 32.4 ± 17.1 with Dmean ≥50 Gy. Based on logistic regression models, during-treatment dose corrections back to planned values may confer ≥5% decrease in the absolute risk of self-reported physical dysphagia symptoms ≥1 year post-treatment in 1.2% of patients, with a ≥5% decrease in relative risk in 23.3% of patients.…”

Practical facility-level approaches to reduce the malaria test positivity rate in Oyo State, Nigeria dataset.csv by Esther Oluwayemisi Ayandipo (18777193)

“…A review of the period from January to December 2021 showed a decrease in TPR from 53%-29%, compared to January to December 2022 with TPR decrease from 25%-31%. …”