Effects of the activation and inhibition of NOTCH signalling on spinal cord progenitor cell proliferation and neuronal generation. by Barbara Hämmerle (36261)

“…<p>A–A′. Confocal projection over 50 µm at the level of the 12^th and 13^th somites of an HH13 embryo that was electroporated with NICD at stage HH10. …”

The Gc fusion loops. by Pablo Guardado-Calvo (2325709)

“…VLPs were incubated with liposomes labeled with a fluorescent dye (DPH, see <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1005813#sec013" target="_blank">Materials and Methods</a>) at pH 7.4 or 5.5. Fractions of the step gradient sedimentation were examined for the presence of Gc by western blot and liposomes by fluorescence. …”

Quantitative PCR validation of mitochondrial genes. by Kwang H. Choi (121395)

“…<p>A scatter plot with a line of best fit demonstrates that each gene in the PFC shows either increase or decrease in expression across age (qv <0.05). …”

Inhibitors of 5-LOX block TRPM7-mediated cell rounding. by Hsiang-Chin Chen (247146)

“…An asterisk indicates treatments that produced a decrease in cell rounding that was significantly different from 293-TRPM7 cells grown in tetracycline.…”

MCCD ventilation - Case-Figure 7 by Stefan Schaller (4976000)

“…The drop in the ventilation rate between 18:50 and 19:10 minutes was due to a leak in the airway circuit. …”

Sensitivity Analysis of Increasing Baseline Effectiveness of Self-Administered Antiretroviral Therapy. by Caitlin J. McCabe (365598)

“…As the proportion of women who have a full response to self-administered HAART increases, there is a decrease in the proportion of women for whom DOT is cost-effective. …”

Sensitivity analysis. by Billy J. Gardner (10988034)

“…<p>The plot shows how much R_t changes from a 10% increase (red) or 10% decrease (blue) in that model parameter relative to values in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1009122#pcbi.1009122.t001" target="_blank">Table 1</a> (with τ_Is = 0.2 and κ = 1). …”

Total fluorescence of Z-RR-AMC and Z-FR-AMC cleavage by planaria lysate is reduced by inhibition of cathepsin activity. by Louise S. Goupil (2922159)

“…<p><b>(A)</b> Whole worm lysate was pre-incubated with 50μM E-64, a pan-cysteine protease inhibitor, before assaying with the fluorescent probe Z-RR-AMC. …”

Regulation of nestin expression by thrombin and cell density in cultures of bone mesenchymal stem cells and radial glial cells-3 by Franz Wautier (86113)

“…Protein extracts were separated and revealed with anti-nestin and anti-actin antibodies. A decrease of nestin expression is apparent from an initial density of 50·10cells/cm(G). …”

mast cell quantification raw data.xlsx by Soumya Gupta (14513114)

“…</p> <p><br></p> <p>1.jpg : apalstic anemia, magnification 4X, hematoxylin and eosin staining</p> <p>2.jpg: metachromatically stained mast cells, magnification 10X, Toluidine Blue staining</p> <p>3.jpg: metachromatically stained mast cells, magnification 20X, Toluidine Blue staining</p> <p>4.jpg: metachromatically stained mast cells, magnification 40X, Toluidine Blue staining</p> <p>5.jpg : MDS-h, hypoplastic marrow, magnification 4X, hematoxylin and eosin staining</p> <p>6.jpg: metachromatically stained mast cells, magnification 40X, Toluidine Blue staining</p> <p><br></p> <p>File: procedure of CD34 IHC staining</p> <p>this file provides the step by step procedure for CD34 IHC satining including te reagents used and time frames.…”

Supplementary files by Ali nasith (20645786)

“…Forest plot was made using Review manager v5.4 with Odds ratio as measure effect. The inclusion study characteristics and findings from each study were summarised in an extraction table and then synthesised qualitatively. …”

Data_Sheet_3_Cardiorespiratory Alterations in a Newborn Ovine Model of Systemic Inflammation Induced by Lipopolysaccharide Injection.PDF by Stéphanie Nault (846680)

“…Two 6-h polysomnographic recordings were performed on two consecutive days on eight full-term lambs: the first after an IV saline injection (control condition, CTRL); the second, after an IV injection of 2.5 μg/kg Escherichia coli LPS 0127:B8 (LPS condition). …”

Data_Sheet_1_The timelines for the price and reimbursement authorization in Italy 2018–2020.pdf by Valentina Gallo (95843)

“…In 2020, the overall process duration for Off-patent pharmaceuticals procedures was equal to 129.8 average days [95% CI: (122.3–137.2)], with a median value of 108.0, whereas for In-patent pharmaceuticals procedures, it was equal to 283.1 average days [95% CI: (267.8–298.5)], with a median value of 284.0. Over time, the trend of the entire duration of the P&R process tended to decrease. …”

An <em>IL28B</em> Genotype-Based Clinical Prediction Model for Treatment of Chronic Hepatitis C by Thomas R. O'Brien (214533)

“…Subjects were re-treated with pegylated-interferon/ribavirin during trial lead-in. We used step-wise logistic regression to calculate adjusted odds ratios (aOR) and create the predictive model. …”

Localization of anti-TG2 scFvs after intraventricular delivery and footprint analysis. by Sabrina Boscolo (251883)

“…Mice treated with monoclonal antibodies were tested at 5 h, after antibody injection for gait imbalance with footprint analysis. …”

Single-molecule properties of the Head1/Neck3 chimera. by Sarah Adio (374199)

“…Motors were observed for 5 sec with an integration time of 200 ms at an ATP concentration of 20 µM. …”

Data_Sheet_2_Cardiorespiratory Alterations in a Newborn Ovine Model of Systemic Inflammation Induced by Lipopolysaccharide Injection.PDF by Stéphanie Nault (846680)

“…Two 6-h polysomnographic recordings were performed on two consecutive days on eight full-term lambs: the first after an IV saline injection (control condition, CTRL); the second, after an IV injection of 2.5 μg/kg Escherichia coli LPS 0127:B8 (LPS condition). …”

DataSheet1_Causal effects and metabolites mediators between immune cell and risk of colorectal cancer: a Mendelian randomization study.docx by Qian Yang (300330)

“…</p>Methods<p>We employed a two-sample bidirectional Mendelian randomization (MR) approach to assess the causal influence of immune cells on CRC. Additionally, a two-step MR strategy was utilized to pinpoint potential metabolites that mediate this effect. …”

The Cellular and Molecular Basis of Bitter Tastant-Induced Bronchodilation by Cheng-Hai Zhang (385288)

“…We show that these Ca²⁺ changes in cells at rest are mediated via activation of the canonical bitter taste signaling cascade (i.e., TAS2R-gustducin-phospholipase Cβ [PLCβ]- inositol 1,4,5-triphosphate receptor [IP3R]), and are not sufficient to impact airway contractility. …”

Data_Sheet_1_Cardiorespiratory Alterations in a Newborn Ovine Model of Systemic Inflammation Induced by Lipopolysaccharide Injection.PDF by Stéphanie Nault (846680)

“…Two 6-h polysomnographic recordings were performed on two consecutive days on eight full-term lambs: the first after an IV saline injection (control condition, CTRL); the second, after an IV injection of 2.5 μg/kg Escherichia coli LPS 0127:B8 (LPS condition). …”